Selected Publications Since 2013
Madugula, K., Demarino, C., Ginwala, R., Teixeira, V., Joseph, J., Khan, Z.K., Sales, D., Kashanchi, F., Rushing, A.W., Lemasson, I., Harhaj, E.W., Janakiram, M., Ye, B.H., and Jain, P. Regulation of HTLV-1 3'LTR antisense promoter by Myocyte Enhancer Factor-2C in the context of Ault T-cell leukemia and lymphoma. Haematologica. 2022 107(12):2928-2943. doi: 10.3324/haematol.2021.279542.
Kogure, Y., Kameda, T., Koya1, J., Yoshimitsu, M., Nosaka, K., Yasunaga, J-I., Imaizumi, Y., Watanabe, M., Saito, Y., Ito, Y., McClure, M.B., Tabata, M., Shingaki, S., Yoshifuji, K., Chiba, K., Okada, A., Kakiuchi, N., Nannya, Y., Kamiunten, A., Shide, K., Hidaka, T., Kubuki, Y., Kitanaka, A., Hidaka, M., Utsunomiya, A., Ramos, J.C., Shibata, T., Takeuchi, K., Takaori-Kondo, A., Miyazaki, Y., Matsuoka, M., Ishitsuka, K., Shiraishi, Y., Miyano, S., Ogawa, S., Ye, B.H.*, Shimoda, K.*, and Kataoka, K.*. Whole-genome landscape of adult T-cell leukemia/lymphoma. *communication authors. Blood 2022 139(7):967-982. doi: 10.1182/blood.2021013568. PMID: 34695199
Shah, U.A., Shah, N., Qiao, B., Acuna-Villaorduna, A., Pradhan, K, Sica, A., Shastri, A., Mantzaris, I., Derman, O., Kornblum, N., Braunschweig, I., Ye, B.H., Verma, A., Janakiram, M. Epidemiology and survival trend of Adult T-cell Leukemia/Lymphoma in the United States: An Analysis of the NPCR, SEER, and NYSCR datasets. Cancer. 2020 Feb 1;126(3):567-574. doi: 10.1002/cncr.32556. PMID: 31769871
Rauch, D.A., Conlon, K.C., Janakiram, M., Brammer, J.E., Harding, J.C., Ye, B.H., Zang, X., Ren, X., Olson, S., Cheng, X., Miljkovic, M.D., Sundaramoorth, H., Joseph, A., Griffith, M., Waldmann, T.A., and Ratner, L. Rapid Progression of Adult T-Cell Leukemia/Lymphoma as Tumor Infiltrating Treg Cells after PD-1 Blockade. Blood. 2019. 134:1406-1414. doi: 10.1182/blood.2019002038. PMID: 31467059
Chung EY, Mai Y, Shah UA, Wei Y, Ishida E, Kataoka K, Ren X, Pradhan K, Bartholdy B, Wei X, Zou Y, Zhang J, Ogawa S, Steidl U, Zang X, Verma A, Janakiram M, Ye BH. PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma. Clin Cancer Res. 25:3589–601, 2019. PMID: 30862694 (Cover Article). [PDF Full Text]
Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, Bartenstein M, Goel S, Mantzaris I, Shastri A, Derman O, Binder A, Gritsman K, Kornblum N, Braunschweig I, Bhagat C, Hall J, Graber A, Ratner L, Wang Y, Ogawa S, Verma A*, Ye BH*, Janakiram M*. North American ATLL has a Distinct Mutational and Transcriptional Profile and responds to epigenetic therapies. Blood. 2018 Aug 13. pii: blood-2018-01-824607. doi: 10.1182/blood-2018-01-824607. PMID: 30104217. * communication authors. [PDF Full Text]
Mai Y, Yu JJ, Bartholdy B, Xu-Monette ZY, Knapp EE, Yuan F, Chen H, Ding BB, Yao Z, Das B, Zou Y, Young KH, Parekh S, Ye BH. Subtype-specific mechanism for Doxorubicin-triggered cytotoxicity in diffuse large B cell lymphomas. Blood. 128(24):2797-2807, 2016. PMID: 27737889. [PDF FULL Text]
Alvarez, M. J., Shen, Y., Giorgi, F.M., Lachmann, A., Ding, B.B., Ye, B.H., Califano, A. Network-based inference of protein activity helps functionalize the genetic landscape of cancer. Nature Genet, 48(8):838-4, 2016. PMID: 27322546. [PDF Full Text]
Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Ansel KM, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M. Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia. Cancer Cell. 27(3):409-25, 2015. PMID: 25759025. [PDF Full Text]
Zhao, H., Bauzon, F., Bi, E., Yu, J.J., Fu, H., Lu, Z., Cui, J., Jeon, H., Zang, X., Ye, B.H. and Zhu, L. Mutating Threonine 187 of p27 To An Alanine Prevents Pituitary Tumorigenesis By Two-Hit Loss Of Rb1 And Enhances Humoral Immunity In Old Age. J Biol Chem. 290(9):5787-809. 2015. PMID: 25583987, PMCID: PMC4342489.[PDF Full Text]
Wei, X., Xu, M., Wei, Y., Huang, F., Zhao, T., Li, X., Feng, R.*, and Ye, B.H.* The addition of rituximab to CHOP therapy altered the prognostic significance of CD44 expression. (*Communication authors). J Hematol Oncol. 7(1):34-36, 2014. PMID: 24739401, PMCID: PMC4022142. [PDF Full Text]
Huang, X., Meng, B., Iqbal, J., Ding, B.B., Perry, A.M., Cao, W., Smith, L.M., Bi, C., Jiang, C., Greiner, T.C., Weisenburger, D., Rimsza, L., Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R., Gascoyne, R., Cook, J., Tubbs, R., Jaffe, E., Armitage, J., Vose, J., Staudt, L., McKeithan, T.W., Chan, W., Ye, B.H.*, Fu, K*. Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma patients treated with R-CHOP. J Clin Oncol., 31:4520-8, 2013 (*communication authors). [PDF Full Text]
Ye, B.H., Mai, Y. A Bach2 Link between Pre-B Cell Receptor Checkpoint and Pre-B Cell ALL. Cancer Cell. 2013 24(3):282-4. [PDF Full Text]
Ding, B.B., Bi, E., Chen, H., Yu, J.J. and Ye, B.H. IL-21/STAT3 and CD40L/NF-kappaB synergistically promote plasma cell differentiation through upregulation of Blimp-1. J Immunol. 190(4):1827-36, 2013. [PDF Full Text]