Members

Praveen Agrawal, Ph.D.

Praveen Agrawal, Ph.D.

718.430.2604

CDTMI Relevant Areas of Research: Role of altered glycosylation in tumor progression, metastasis and resistance to targeted therapy in melanoma and prostate cancer, tumor microenvironment, organ tropism in metastasis, effect of glycan branching on glycoprotein function

View Profile

Julio A. Aguirre-Ghiso, Ph.D.

Julio A. Aguirre-Ghiso, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Director, Institute for Cancer Dormancy and Tumor Microenvironment

718.678.1246

CDTMI Relevant Areas of Research: Metastasis biology Cancer cell dormancy Signal transduction Extracellular matrix Innate immune cell function tumor and normal organ microenvironment

View Profile

Nir Barzilai, M.D.

Nir Barzilai, M.D.

Professor, Department of Medicine (Endocrinology)

Professor, Department of Genetics

Ingeborg and Ira Leon Rennert Chair in Aging Research

Director, Institute for Aging Research

718.430.3144

CDTMI Relevant Areas of Research: We study the genetic of longevity, hypothesizing that centenarians have protective genes that allows the delay of aging and protect against age-related diseases.

View Profile

Teresa V. Bowman, Ph.D.

Teresa V. Bowman, Ph.D.

Associate Professor, Department of Developmental & Molecular Biology

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

718.430.4001

CDTMI Relevant Areas of Research: Mechanisms of hematopoietic stem cells formation and regeneration; pre-mRNA splicing regulation of hematopoiesis; identification of novel therapeutics for myelodysplastic syndrome

View Profile

Dongsheng Cai, M.D., Ph.D.

Dongsheng Cai, M.D., Ph.D.

Professor, Department of Molecular Pharmacology

Young Men's Division Chair in Physiology

Director, Institute for Neuroimmunology and Inflammation

718.430.2426

CDTMI Relevant Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease.

View Profile

Edward Chu, M.D., M.M.S.

Edward Chu, M.D., M.M.S.

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Professor, Department of Molecular Pharmacology

Interim Chair Department of Oncology

Director, Albert Einstein Cancer Center

718.430.2303

View Profile

John S. Condeelis, Ph.D.

John S. Condeelis, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Surgery

The Judith and Burton P. Resnick Chair in Translational Research Department of Anatomy & Structural Biology

Chair Emeritus Department of Anatomy & Structural Biology

Co-Director, Gruss-Lipper Biophotonics Center

Co-Director, Integrated Imaging Program

Director, Tumor Microenvironment and Metastasis Program AECC

Scientific Director, Analytical Imaging Facility

718.430.2718

CDTMI Relevant Areas of Research: Interests are in optical physics, cell biology and biophysics, cancer biology and mouse models of cancer. Development of the multiphoton imaging technology used to identify intravasation microenvironments in metastatic tumors

View Profile

Dianne Cox, Ph.D.

Dianne Cox, Ph.D.

718.430.3019

CDTMI Relevant Areas of Research: Macrophages are important in immune function but they can also play negative roles, such as in chronic inflammatory disease, and in cancer progression. Our lab studies the mechanisms of macrophage recruitment and function.

View Profile

Sofia de Oliveira, Ph.D.

Sofia de Oliveira, Ph.D.

Assistant Professor, Department of Developmental & Molecular Biology

Assistant Professor, Department of Medicine (Hepatology)

718.430.4294

CDTMI Relevant Areas of Research: Our lab studies neutrophils and their role in disease progression. We are particularly interested in unveiling how the presence of systemic inflammation and metabolic dysregulation found in metainflammation and inflammaging settings alter the neutrophils

View Profile

Antonio Di Cristofano, Ph.D.

Antonio Di Cristofano, Ph.D.

Professor, Department of Developmental & Molecular Biology

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

718.678.1137

CDTMI Relevant Areas of Research: Cancer Biology; utilizing in vivo models to study signaling pathways altered in advanced thyroid cancer; development of novel therapeutic strategies based on the tumor molecular landscape; tumor/microenvironment interaction

View Profile

David R. Entenberg, Ph.D.

David R. Entenberg, Ph.D.

Assistant Professor, Department of Pathology

Director of Engineering & Operations for the Gruss Lipper Biophotonics Center

Director of Engineering & Operations for the Integrated Imaging Program

Director of Technological Development Department of Anatomy & Structural Biology

Director of Integrated Imaging Department of Anatomy & Structural Biology

718.678.1116

CDTMI Relevant Areas of Research: Development of photonics based assays for metastasis research. Specific areas of focus include: intravital imaging, quantitative digital pathology, biomarker development and validation, and surgical engineering.

View Profile

David R. Fooksman, Ph.D.

David R. Fooksman, Ph.D.

Associate Professor, Department of Pathology

Associate Professor, Department of Microbiology & Immunology

718.839.7957

CDTMI Relevant Areas of Research: In vivo plasma cell differentiation, migration, and physiology; multiple myeloma; hematopoietic stem cells, Intra-vital multi-photon imaging technology, tumor microenvironment, cellular immunology

View Profile

Matthew J. Gamble, Ph.D.

Matthew J. Gamble, Ph.D.

718.430.2942

CDTMI Relevant Areas of Research: Histone variant macroH2A; Cancer; Cellular senescence; Chromatin structure and function; Transcription; Splicing; Senescence-associated secretory phenotype; Endoplasmic reticulum stress responses; Poly(ADP-ribose) polymerase

View Profile

Evripidis Gavathiotis, Ph.D.

Evripidis Gavathiotis, Ph.D.

Professor, Department of Biochemistry

Professor, Department of Medicine (Cardiology)

718.430.3725

CDTMI Relevant Areas of Research: chemical biology, structural biology, medicinal chemistry, drug discovery, BCL-2 family proteins, protein-protein interactions, kinase signaling, cell death, apoptosis, mitochondria, autophagy, cancer, aging

View Profile

John M. Greally, Ph.D., D.Med., M.B.,B.Ch.,B.A.O.

John M. Greally, Ph.D., D.Med., M.B.,B.Ch.,B.A.O.

Professor, Department of Genetics

Professor, Department of Pediatrics (Pediatric Genetic Medicine)

Chief, Department of Genetics Division of Genomics

Director, Center for Epigenomics

Faculty Scholar for Epigenomics

Faculty Advisor, Department of Genetics Computational Genomics Core

Faculty Advisor, Department of Genetics Epigenetics Shared Facility

718.678.1234

CDTMI Relevant Areas of Research: Medical genomics: the delivery of genomic information to enhance the health of the diverse Bronx population. Transcriptional regulation/epigenetics: understanding how the regulation of the genome is influenced by genetic and environmental variation.

View Profile

Kira Gritsman, M.D., Ph.D.

Kira Gritsman, M.D., Ph.D.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Cell Biology

929.246.6707

CDTMI Relevant Areas of Research: roles of signaling pathways in hematopoietic stem cell self-renewal and differentiation, leukemic stem cells, targeting signaling pathways in hematologic malignancies

View Profile

Wenjun Guo, Ph.D.

Wenjun Guo, Ph.D.

Associate Professor, Department of Cell Biology

718.678.1276

CDTMI Relevant Areas of Research: Breast cancer stem cells, mammary stem cells, mammary development, cellular plasticity, metastasis, therapeutic resistance

View Profile

Rachel Hazan, Ph.D.

Rachel Hazan, Ph.D.

718.430.3349

CDTMI Relevant Areas of Research: My laboratory is currently investigating the molecular basis for breast cancer metastasis by studying the cooperation between N-cadherin and the FGFR leading to epithelial to mesenchymal transition and cancer cell survival.

View Profile

Keisuke Ito, M.D., Ph.D.

Keisuke Ito, M.D., Ph.D.

Associate Professor, Department of Cell Biology

Associate Professor, Department of Medicine

Director of Scientific Resources of the Stem Cell Institute

718.678.1278

CDTMI Relevant Areas of Research: Hematopoietic stem cells (HSCs) and Stem cell fate; Myelodysplastic syndrome (MDS) and hematological malignancies; Stem cell metabolisms and epigenetics; Bone marrow microenvironment; Sickle cell disease and vaso-occlusion

View Profile

Georgios Karagiannis, Ph.D.

Georgios Karagiannis, Ph.D.

718.430.2967

CDTMI Relevant Areas of Research: Molecular/Cellular Responses of Tumor and Immune Microenvironments to Cytotoxic Chemotherapy

View Profile

David M. Loeb, M.D., Ph.D.

David M. Loeb, M.D., Ph.D.

Professor, Department of Pediatrics (Pediatric Hematology-Oncology)

Professor, Department of Developmental & Molecular Biology

Chief, Department of Pediatrics Division of Pediatric Hematology / Oncology

718.920.4664

CDTMI Relevant Areas of Research: Dr. Loeb has a translational research laboratory focused on the biology and treatment of bone tumor metastasis, especially the role of Wnt signaling pathways. Other areas of interest include the role of the RNA helicase, DDX3, in bone sarcomas and the met

View Profile

Maria Marianovich, Ph.D.

Maria Marianovich, Ph.D.

Assistant Professor, Department of Cell Biology

718.678.1066

CDTMI Relevant Areas of Research: Hematopoietic stem cell and cancer stem cell microenvironment. Our lab studies mechanisms that regulate the maintenance of bone marrow niches for hematopoietic stem cells during homeostasis, aging, or myeloid malignancy.

View Profile

John C. McAuliffe, M.D., Ph.D.

John C. McAuliffe, M.D., Ph.D.

Assistant Professor, Department of Surgery

Assistant Professor, Department of Pathology

718.379.6865

CDTMI Relevant Areas of Research: Microenvironment and metastasis in Pancreas Cancer and Neuroendocrine Tumors

View Profile

Hayley M. McDaid, Ph.D.

Hayley M. McDaid, Ph.D.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Molecular Pharmacology

718.430.8829

CDTMI Relevant Areas of Research: Breast, Lung and Ovarian Cancer, Experimental Therapeutics, Intrinsic and Acquired Drug Resistance, Tubulin ligands, Cancer and Senescence, Senolytics, Biomarker Development

View Profile

Satish K. Nandakumar, M.B.B.S., Ph.D.

Satish K. Nandakumar, M.B.B.S., Ph.D.

Assistant Professor, Department of Cell Biology

718.430.2815

CDTMI Relevant Areas of Research: Germline predisposition to blood cancers, Hematopoietic stem cells, Clonal hematopoiesis, Myeloproliferative neoplasms, Genetic variants, Enhancer elements, CRISPR/Cas9 edited stem cell models, Multiplexed functional assays.

View Profile

Maja H. Oktay, M.D., Ph.D.

Maja H. Oktay, M.D., Ph.D.

718.920.4269

CDTMI Relevant Areas of Research: Tumor progression and metastasis; The effect of chemotherapy and endocrine therapy on breast cancer microenvironment; Racial disparity in cancer.

View Profile

Jeffrey E. Segall, Ph.D.

Jeffrey E. Segall, Ph.D.

Professor, Department of Pathology

Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research

718.430.2484

CDTMI Relevant Areas of Research: mechanisms of tumor cell invasion, intravasation and metastasis; macrophage tumor cell interactions; breast cancer; head and neck cancer; glioblastoma; intravital imaging; KIF9; APOE; cholesterol; neuregulin; JAG1; miR-375

View Profile

Aditi Shastri, M.B.B.S.

Aditi Shastri, M.B.B.S.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Developmental & Molecular Biology

718.920.4826

CDTMI Relevant Areas of Research: acute myeloid leukemia, myelodysplastic syndromes, cancer stem cells, transcription factors, STAT3, RNA biology and therapeutic interference, health disparities

View Profile

Ulrich G. Steidl, M.D., Ph.D.

Ulrich G. Steidl, M.D., Ph.D.

Professor, Department of Cell Biology

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Rose C. Falkenstein Chair in Cancer Research

Deputy Director, and Associate Director for Basic Science Albert Einstein Cancer Center

Interim Director, The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research

The Diane and Arthur B. Belfer Faculty Scholar in Cancer Research

Co-Director, Blood Cancer Institute

718.430.3437

CDTMI Relevant Areas of Research: hematopoiesis; cancer; stem cell origin of cancer; leukemia; AML; MDS; MPN; hematopoietic stem cells (HSC); preleukemic stem cells; transcription; transcription dynamics; molecular noise; epigenetics; targeted therapy; drug development; translational comp

View Profile

Brendon M. Stiles, M.D.

Brendon M. Stiles, M.D.

Professor, Department of Cardiothoracic & Vascular Surgery

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

718.920.5732

CDTMI Relevant Areas of Research: Basic/Translational: Tumor microenvironment, Mono-ADP-ribosylation, ART1 Predictors of response to immunotherapy. Clinical: Lung cancer, Lung cancer screening, Neoadjuvant therapy,

View Profile

Amit K. Verma, M.B.B.S.

Amit K. Verma, M.B.B.S.

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Professor, Department of Developmental & Molecular Biology

Director, Division of Hemato-Oncology Montefiore Department of Oncology

718.430.8761

CDTMI Relevant Areas of Research: Myelodysplastic syndrome (MDS) are hematologic malignancies characterized by ineffective hematopoiesis. We study the molecular pathogenesis of MDS to identify targetable pathways for treatment of this disease.

View Profile

Britta Will, Ph.D.

Britta Will, Ph.D.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Cell Biology

718.430.3786

CDTMI Relevant Areas of Research: Hematopoietic Stem Cells (HSC), Regulation of Stem Cell Fate, Aging, Myelodysplastic Syndrome and Acute Myeloid Leukemia, Mouse Models of Leukemogenesis, Testing of novel stem cell-directed therapeutics on primary human HSCs.

View Profile

Xingxing Zang, Ph.D.

Xingxing Zang, Ph.D.

Professor, Department of Microbiology & Immunology

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Professor, Department of Urology

Louis Goldstein Swan Chair in Women's Cancer Research

718.430.4155

CDTMI Relevant Areas of Research: New T cell immune checkpoints; Cancer immunotherapy; Autoimmune diseases and immunotherapy; Metabolic diseases and immunotherapy; Infection and vaccines

View Profile