Einstein/Montefiore Department of Medicine

Grand Rounds

Medicine Grand Rounds: Autoimmune Statin Myopathy in Evolution

Einstein/Montefiore Department of Medicine Grand Rounds

Thursday, April 21, 2016

8:00 AM: Forchheimer Medical Science Building 3rd Floor Lecture Hall

Speaker & Info

Lisa Christopher-Stine, MD
Director, Johns Hopkins Myositis Center
Associate Professor of Medicine
Associate Professor of Neurology
Johns Hopkins

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Repeated at 12:15 pm, Cherkasky Auditorium, Montefiore Medical Center.

Dr. Christopher-Stine is an Associate Professor of Medicine and Neurology and the Director of the Johns Hopkins Myositis Center, a multidisciplinary clinic formally established in 2007 on the Johns Hopkins Bayview campus. She completed a BA in chemistry cum laude at Franklin and Marshall College; medical school at Hahnemann University School of Medicine, where she was elected to Alpha Omega Alpha; and an MPH at Johns Hopkins Bloomberg School of Public Health; internship and residency training at MCP Hahnemann University, where she also served as Chief Resident; and rheumatology fellowship training at Johns Hopkins. She joined the faculty in the Division of Rheumatology at Johns Hopkins in 2003.

Over the past 12 years, Dr. Christopher-Stine has been involved in clinical research related to idiopathic inflammatory myopathies ("myositis") and has authored or co-authored over 50 publications. She and her colleagues recently discovered that some statin-related myopathies are, in fact, autoimmune in nature. This discovery is a true example of the excellent collaboration and translational research opportunities at Johns Hopkins that has helped to solve a medical mystery and has benefitted patients directly.

As a clinician scientist, Dr. Christopher-Stine utilizes the myositis database developed by her and her colleagues, currently numbering over 2000 patients recruited worldwide. She has a strong interest in patient- reported outcomes. In addition, she teaches both formally and informally at all levels of medical education from students to fellows to faculty. She takes pleasure in the interplay of her roles as clinician, scientist, and educator.

Objectives - After attending this activity, participants will be able to:

  1. Describe a brief historical overview of statins
  2. Elucidate current knowledge about self-limited "statin myopathy" and how to address it in clinical practice
  3. Analyze when to suspect the rare anti-HMGCR-associated immune mediated statin myopathy and to recognize how to distinguish it from the self-limited form

Accreditation: Albert Einstein College of Medicine designates this educational activity for a maximum of 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity. Albert Einstein College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Host: Division of Rheumatology (Department of Medicine)

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