Faculty

Department Chair

Steven C. Almo, Ph.D.

Steven C. Almo, Ph.D.

Professor, Department of Biochemistry

Chair Department of Biochemistry

Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology

Director, Einstein Macromolecular Therapeutics Developmental Facility

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Cancer Therapeutics Program

718.430.2746

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Lab Heads

Michael D. Brenowitz, Ph.D.

Michael D. Brenowitz, Ph.D.

718.430.3179

Areas of Research: Exploring how protein, DNA, and RNA structure, folding, and assembly determines the biological function of these macromolecules.

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Anne R. Bresnick, Ph.D.

Anne R. Bresnick, Ph.D.

Professor, Department of Biochemistry

Associate Dean for Postdoctoral Affairs

Director, Belfer Institute for Advanced Biomedical Studies

Associate Director, Cancer Research Training and Education Montefiore Einstein Comprehensive Cancer

718.430.2741

Areas of Research: Mechanisms mediating tumor cell migration, invasion and metastasis; development of novel drugs that target cell migration; regulation of the actin-based cytoskeleton

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Maureen J. Charron, Ph.D.

Maureen J. Charron, Ph.D.

718.430.2852

Areas of Research: Developmental origin of obesity and diabetes, high fat diet and obesity, animal models of metabolic disease, epigenetics and DNA methylation, glucose transporters and glucagon receptor

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David Cowburn, Ph.D.

David Cowburn, Ph.D.

718.430.8621

Areas of Research: Structural molecular biology; structure/function relationships in the immune system, signal transduction, and nuclear transport; NMR; integration of simulation of time dependent processes and experiments; protein engineering.

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Evripidis Gavathiotis, Ph.D.

Evripidis Gavathiotis, Ph.D.

Professor, Department of Biochemistry

Professor, Department of Medicine (Cardiology)

Professor, Department of Oncology (Medical Oncology)

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Cancer Therapeutics Program

718.430.3725

Areas of Research: chemical biology, structural biology, medicinal chemistry, drug discovery, BCL-2 family proteins, protein-protein interactions, kinase signaling, cell death, apoptosis, mitochondria, autophagy, cancer, aging

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Arne Gennerich, Ph.D.

Arne Gennerich, Ph.D.

718.430.4287

Areas of Research: Molecular mechanisms of microtubule-based motor proteins in health and disease, transcription elongation by RNA polymerases I, II and III, single-molecule biophysics, development and application of single-molecule technologies.

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Seiya Kitamura, Ph.D.

Seiya Kitamura, Ph.D.

Assistant Professor, Department of Biochemistry

718.430.3096

Areas of Research: Chemical Biology, medicinal chemistry, and drug discovery

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Jonathan R. Lai, Ph.D.

Jonathan R. Lai, Ph.D.

Professor, Department of Biochemistry

Dan Danciger Professor of Biochemistry

718.678.1024

Areas of Research: Protein chemistry, antibody engineering, antibody isolation, vaccine design, immunotherapy, virology

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Denis L. Rousseau, Ph.D.

Denis L. Rousseau, Ph.D.

718.430.3592

Areas of Research: Cytochrome c oxidase structure, function and dynamics. Catalytic mechanism of the membrane-bound enzymes probed by time resolved resonance Raman scattering, time resolved X-ray crystallography and cryogenic electron microscopy.

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Vern L. Schramm, Ph.D.

Vern L. Schramm, Ph.D.

Professor, Department of Biochemistry

Ruth Merns Chair in Biochemistry

718.430.2813

Areas of Research: Enzymatic transition states are solved by isotope effects and quantum chemistry. This knowledge permits drug design for cancers, antibiotics and other disorders. Protein dynamics in catalysis is a second focus.

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David Shechter, Ph.D.

David Shechter, Ph.D.

718.430.4120

Areas of Research: Chromatin biology and epigenetics; structural and post-translational regulation of histone chaperones; molecular mechanisms and biological function of protein arginine methyltransferases; intrinsic disorder and structural biology; RNA transcription, splic

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Simone Sidoli, Ph.D.

Simone Sidoli, Ph.D.

Assistant Professor, Department of Biochemistry

718.430.3475

Areas of Research: Chromatin biology, proteomics, mass spectrometry

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Hernando J. Sosa, Ph.D.

Hernando J. Sosa, Ph.D.

718.430.3456

Areas of Research: Structure and function of the cytoskeleton. Biological molecular motors. Kinesins. Structural biology. Cryo-electron microscopy. Single molecule florescence microscopy.

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Howard M. Steinman, Ph.D.

Howard M. Steinman, Ph.D.

Professor, Department of Biochemistry

Assistant Dean for Biomedical Science Education

718.430.3010

Areas of Research: Bacterial pathogenesis, Legionnaires'Disease, Legionella pneumophila, Medical education

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Ian M. Willis, Ph.D.

Ian M. Willis, Ph.D.

718.430.2839

Areas of Research: RNA polymerase III transcription and its repression by Maf1; Mechanisms of obesity resistance in Maf1 knockout mice; Mechanisms of neurodegeneration in Pol III-related leukodystrophy

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Syun-Ru Yeh, Ph.D.

Syun-Ru Yeh, Ph.D.

718.430.4234

Areas of Research: Spectroscopy; Crystallography; High throughput screening; Medicinal chemistry; Protein engineering; Computational biology

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Secondary Faculty

Jonathan M. Backer, M.D.

Jonathan M. Backer, M.D.

Professor, Department of Molecular Pharmacology

Professor, Department of Biochemistry

Chair Department of Molecular Pharmacology

William S. Lasdon Chair in Pharmacology Department of Molecular Pharmacology

Associate Director, Shared Resources Montefiore Einstein Comprehensive Cancer Center

718.430.2153

Areas of Research: Signal transduction; Phosphoinositide kinases; Tumor metastasis; Vesicular trafficking; macropinocytosis

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Andras Fiser, Ph.D.

Andras Fiser, Ph.D.

718.678.1068

Areas of Research: receptor-ligand recognition in the immunological synapse; protein structure modeling and design; transcription factor recognition of cognate DNA binding sites; modeling of gene regulatory networks;

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Victor B. Hatcher, Ph.D.

Victor B. Hatcher, Ph.D.

Professor, Department of Biochemistry

Professor, Department of Medicine

Associate Dean for Continuing Professional Development

Associate Dean for Research Administration

718.920.6674

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Victor L. Schuster, M.D.

Victor L. Schuster, M.D.

Professor, Department of Medicine (Nephrology)

Professor, Department of Biochemistry

Senior Associate Dean

Ted and Florence Baumritter Chair in Medicine

718.430.2910

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Emeritus Faculty

Robert Callender, Ph.D.

Robert Callender, Ph.D.

Professor Emeritus, Department of Biochemistry

718.430.2814

Areas of Research: Enzymology, mechanism and function of enzymes, protein structure and dynamics, drug design

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Mark E. Girvin, Ph.D.

Mark E. Girvin, Ph.D.

Professor Emeritus, Department of Biochemistry

718.430.2724

Areas of Research: Membrane protein structure and function; bacterial multi-drug resistance efflux pumps; protein NMR spectroscopy

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Other Faculty

Ruth H. Angeletti, Ph.D.

Ruth H. Angeletti, Ph.D.

718.430.3475

Areas of Research: proteomics for basic and translational research

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Sean M. Cahill, Ph.D.

Sean M. Cahill, Ph.D.

Senior Staff Scientist, Department of Biochemistry

718.430.2035

Areas of Research: Nuclear Magnetic Resonance (NMR) of small molecules and biomolecules

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Alev Celikgil, M.D.

Alev Celikgil, M.D.

Staff Scientist, Department of Biochemistry

718.678.1182

Areas of Research: Microarray development for DNA and protein arrays. High-throughput recombinant protein expression in eukaryotic systems and downstream purification operations for endotoxin-free production as part of Macromolecular Therapeutics Development Facility.

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Sarah C. Garrett, Ph.D.

Sarah C. Garrett, Ph.D.

Staff Scientist, Department of Biochemistry

718.678.1082

Areas of Research: High throughput Screening Molecular Biology Protein Expression/Purification Mutagenesis

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Zaher O. Merhi, M.D.

Zaher O. Merhi, M.D.

Research Assistant Professor, Department of Biochemistry

718.430.2853

Areas of Research: 1) Impact of advanced glycation end products and vitamin D on ovarian physiology, 2) Impact of metabolic syndrome, obesity and bariatric surgery on ovarian function. 3) PCOS

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Robyn D. Moir, Ph.D.

Robyn D. Moir, Ph.D.

Research Associate Professor, Department of Biochemistry

718.430.2860

Areas of Research: High throughput yeast genetics; molecular and quantitative biochemical analysis of transcription by RNA polymerase III; mechanism of action of the transcription repressor Maf1in yeast and mouse; RNA biology of Maf1 KO mice.

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Edward Nieves, B.S.

Edward Nieves, B.S.

Senior Staff Scientist Emeritus, Department of Biochemistry

Senior Staff Scientist Emeritus, Department of Developmental & Molecular Biology

Areas of Research: The use of mass spectrometry in biological and biochemical research; areas such as the qualitative and quantitative analysis of proteins and their PTMs, small molecules and unknowns.

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