Nathan Shock Center of Excellence The NIA-supported Einstein Nathan Shock Center (E-NSC) represents a collection of nearly 80 internal and external faculty actively engaged in high-impact science and collaborations in the biology of aging, three innovative, state-of-the-art Research Resource Cores, and extensive opportunities for enrichment and training in aging research. The Nathan Shock Center is structured aroundfour research cores Proteostasis of Aging Protein quality control maintenance and homeostasis Director: Ana Maria Cuervo, M.D. Ph.D. Learn More Health Span Physiologic phenotyping through lifespan Director: Derek Huffman, Ph.D. Learn More Human Multi-omics Data Human high-throughput omics data sharing and technical advising Directors: Jan Vijg, Ph.D. and Nir Barzilai, M.D. Learn More Research Development Ensuring the future of Biology of Aging through mentoring, P&F funding, and education Directors: Rajat Singh, M.B.B.S. and Sofiya Milman, M.D. Learn More Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Publications See More Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome.Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role?Direct diagnostic testing of SARS-CoV-2 without the need for prior RNA extraction.Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes.Chaperone-mediated autophagy sustains haematopoietic stem-cell function.ARDD 2020: from aging mechanisms to interventions.SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing.The evolution of a tropical biodiversity hotspot.Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α.Common diseases alter the physiological age-related blood microRNA profile.