Overview Nathan Shock Center of Excellence The NIA-supported Einstein Nathan Shock Center (E-NSC) represents a collection of nearly 80 internal and external faculty actively engaged in high-impact science and collaborations in the biology of aging, three innovative, state-of-the-art Research Resource Cores, and extensive opportunities for enrichment and training in aging research. The Nathan Shock Center is structured aroundfour research cores Proteostasis of Aging Protein quality control maintenance and homeostasis Director: Ana Maria Cuervo, M.D. Ph.D. and Simone Sidoli, Ph.D. Learn More Health Span Health Span Interventions Core (HSIC) Director: Derek Huffman, Ph.D. Learn More Human Multi-omics Data Human high-throughput omics data sharing and technical advising Directors: Jan Vijg, Ph.D. and Sofiya Milman, M.D. Learn More Research Development Ensuring the future of Biology of Aging through mentoring, P&F funding, and education Director: David Fooksman, Ph.D. and Esperanza Arias-Perez, Ph.D. Learn More Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Publications See More A Histone Code Functionally Linked to Replicative Senescence Recommendations for biomarker data collection in clinical trials by longevity biotechnology companies Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity Cerebral small vessel disease unveils a vascular pathway to motoric cognitive risk in aging Genetic links between multimorbidity and human aging