Reduce the Incidence of HIV

A crucial component of ending the HIV/AIDS epidemic is the development, evaluation and implementation strategies to successfully prevent new infections. ERC-CFAR investigators advance the high priority of the NIH for HIV research, to reduce the incidence of HIV, by developing and testing safe, effective, and affordable biomedical interventions in parallel with establishing and evaluating novel behavioral and social science-based prevention approaches. Our investigators are developing strategies to enhance expanding the uptake and adherence of pre-exposure prophylaxis (PrEP), reduce stigma associated with treatment, expand product delivery options, and implement effective HIV prevention packages. They are also determining the impact of mucosal and microbiome environments on the effectiveness of HIV prevention interventions, as well as evaluating the effectiveness of new strategies for the early diagnosis of infection, such as low-cost self or home testing, to stimulate early initiation into care. Listed below are NIH-funded studies by ERC-CFAR Investigators researching strategies to reduce the incidence of HIV.

 

InvestigatorInstitutionNIH GrantGrant Title
Matthew AkiyamaEinsteinDP2DA053730Leveraging HCV phylogenetic networks to prevent HIV and other blood 
borne infections among people who inject drugs
Amelia EscolanoRockefellerK99AI140770Design of vaccination strategies to elicit broadly neutralizing antibodies 
against HIV-1
Sarit GolubHunter CollegeR01MH123262Synthesizing best practice to accelerate access to emerging HIV 
prevention modalities
Sarit GolubHunter CollegeR01MH123262Synthesizing best practice to accelerate access to emerging HIV 
prevention modalities
Betsy HeroldEinsteinR01HD098977Impact of the vaginal microbiome on topical HIV pre-exposure 
prophylaxis (PrEP)
Pedro Mateu-GelabertCUNY SPHR01DA041501The staying safe intervention: preventing HCV among young opioid 
injectors
Denis NashCUNY SPHR01MH117793PROMISE - Program refinements to optimize model impact and scalability 
based on evidence
Denis NashCUNY SPHR01MH125735Strengthening the safety net: Testing a novel data-to-suppression (D2S) 
intervention strategy in the Ryan White HIV/AIDS Program
Michel NussenzweigRockefellerP01 AI138212Activation of HIV-1 specific B cell precursors using novel vaccine 
approaches
Viraj PatelEinsteinR21MH118102Impact of multiple stigmas on HIV care continuum outcomes for key 
populations
Viraj PatelEinsteinR01MH119001Chalo!: a mobile technology based intervention to accelerate HIV testing 
and linkage to prevention and treatment
Vinayaka PrasadEinsteinR01AI153008CCL2-CCR2B signaling in HIV-1 fitness and disease; role of host genetic 
polymorphisms
Jonathan RossEinsteinK23MH114752Minimizing losses from HIV care under universal treatment in Rwanda
Tyrel StarksHunter CollegeR01DA050508Expanding the potential of couples HIV testing: adjunct modules to reduce 
drug use among male couples
Tyrel StarksHunter CollegeR01DA045613Intervention to reduce drug use and HIV incidence among high prep 
priority partnered YMSM
Gabriel VictoraRockefellerR01AI119006Dynamics of antigen-driven selection in germinal centers