Revealing the Mechanisms of Normal and Malignant Plasma Cells

David R. Fooksman, PhD

David R. Fooksman, PhD

Associate Professor, Department of Pathology

Associate Professor, Department of Microbiology & Immunology


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The laboratory of David R. Fooksman, PhD, focuses on various aspects of normal and malignant plasma cell physiology: how these cells develop, migrate, survive and function in vivo, and in particular in the bone marrow. The bone marrow (BM) is a critical microenvironment that supports and constrains these cells; by understanding the interactions, Dr. Fooksman and his team aim to develop more-effective treatments for cancer as well as better vaccines.

To investigate these questions, the Fooksman laboratory employs cellular immunology techniques, sophisticated mouse models, and custom two-photon intravital imaging tools to visualize and manipulate cells in situ using live mice.

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