Qibin Qi

Qibin Qi, Ph.D.

Area of research

  • Epidemiological studies of obesity and related cariometabolic disease (diabetes and CVD); genetic and gene-environment interaction studies; Metabolomics; Gut Microbiome; cariometabolic disease in HIV infection

Email

Phone

Location

  • Albert Einstein College of Medicine Jack and Pearl Resnick Campus 1300 Morris Park Avenue Belfer Building 1306 Bronx, NY 10461

Lab of Qibin Qi



Research Profiles

Professional Interests

Dr. Qi has a broad background in molecular epidemiology studies with specific training and expertise in genetics, biomarkers and nutrition. Dr. Qi’s current research focuses on multi omics, including metabolomics, genomics and transcriptomics, as well as gut microbiome, in relation to obesity, diabetes and cardiovascular diseases (CVD) in both general populations and under-studied populations (e.g., US Hispanics, HIV-infected populations).

Selected Publications

  • Wang Z, Peters BA, Yu B, Grove ML, Wang T, Xue X, Thyagarajan B, Daviglus ML, Boerwinkle E, Hu G, Mossavar-Rahmani Y, Isasi CR, Knight R, Burk RD, Kaplan RC, Qi Q*. Gut Microbiota and Blood Metabolites Related to Fiber Intake and Type 2 Diabetes. Circulation Research. 2024 Mar 29;134(7):842-854. doi: 10.1161/CIRCRESAHA.123.323634. Epub 2024 Mar 28. PMID: 38547246

  • Zhang Y, Chen GC, Sotres-Alvarez D, Perreira KM, Daviglus ML, Pirzada A, Gallo LC, Llabre MM, Cai J, Xue X, Isasi CR, Kaplan R, Qi Q*. General or Central Obesity and Mortality Among US Hispanic and Latino Adults. JAMA Netw Open. 2024 Jan 2;7(1):e2351070. PMID: 38227314

  • Luo K, Chen GC, Zhang Y, Moon JY, Xing J, Peters BA, Usyk M, Wang Z, Hu G, Li J, Selvin E, Rebholz CM, Wang T, Isasi CR, Yu B, Knight R, Boerwinkle E, Burk RD, Kaplan RC, Qi Q*. Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes. Nature Metabolism. 2024 Jan;6(1):169-186. PMID: 38253929

  • Peters BA, Hanna DB, Wang Y, Weber KM, Topper E, Appleton AA, Sharma A, Hodis HN, Santoro N, Guillemette C, Caron P, Knight R, Burk RD, Kaplan RC, Qi Q. Sex hormones, the stool microbiome, and subclinical atherosclerosis in women with and without HIV. J Clin Endocrinol Metab. 2024 Jan 18;109(2):483-497. PMID: 37643897

  • Zhang Y, Lin CL, Weber KM, Xing J, Peters BA, Sollecito CC, Grassi E, Wiek F, Xue X, Seaberg EC, Gustafson D, Anastos K, Sharma A, Burgess HJ, Burk RD, Qi Q*, French AL. Association of gut microbiota with objective sleep measures in women with and without HIV infection: the IDOze study. J Infect Dis. 2023 Nov 11;228(10):1456-1466. PMID: 37650624.

  • Hua S, Peters BA, Lee S, Fitzgerald K, Wang Z, Sollecito CC, Grassi E, Wiek F, St Peter L, D'Souza G, Weber KM, Kaplan RC, Gustafson D, Sharma A, Burk RD, Rubin LH, Qi Q*. Gut Microbiota and Cognitive Function Among Women Living with HIV. J Alzheimers Dis. 2023;95(3):1147-1161. PMID: 37661881.

  • Wang Z, Peters BA, Bryant M, Hanna DB, Schwartz T, Wang T, Sollecito CC, Usyk M, Grassi E, Wiek F, Peter LS, Post WS, Landay AL, Hodis HN, Weber KM, French A, Golub ET, Lazar J, Gustafson D, Sharma A, Anastos K, Clish CB, Burk RD, Kaplan RC, Knight R, Qi Q*. Gut microbiota, circulating inflammatory markers and metabolites, and carotid artery atherosclerosis in HIV infection. Microbiome. 2023 May 27;11(1):119. PMID: 37237391

  • Peters BA, Xing J, Chen GC, Usyk M, Wang Z, McClain AC, Thyagarajan B, Daviglus ML, Sotres-Alvarez D, Hu FB, Knight R, Burk RD, Kaplan RC, Qi Q. Healthy dietary patterns are associated with the gut microbiome in the Hispanic Community Health Study/Study of Latinos. Am J Clin Nutr. 2023 Mar;117(3):540-552. PMID: 36872018

  • Chen YY, Chen GC, Abittan N, Xing J, Mossavar-Rahmani Y, Sotres-Alvarez D, Mattei J, Daviglus M, Isasi CR, Hu FB, Kaplan R, Qi Q*. Healthy dietary patterns and risk of cardiovascular disease in US Hispanics/Latinos: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Am J Clin Nutr. 2022 Oct 6;116(4):920-927. PMID: 36041183

  • Wang Z, Peters BA, Usyk M, Xing J, Hanna DB, Wang T, Post WS, Landay AL, Hodis HN, Weber K, French A, Golub ET, Lazar J, Gustafson D, Kassaye S, Aouizerat B, Haberlen S, Malvestutto C, Budoff M, Wolinsky SM, Sharma A, Anastos K, Clish CB, Kaplan RC, Burk RD, Qi Q*. Gut Microbiota, Plasma Metabolomic Profiles, and Carotid Artery Atherosclerosis in HIV Infection. Arterioscler Thromb Vasc Biol. 2022 Aug;42(8):1081-1093. PMID: 35678187

  • Chen GC, Chai JC, Xing J, Moon JY, Shan Z, Yu B, Mossavar-Rahman Y, Sotres-Alvarez D, Li J, Mattei J, Daviglus ML, Perkins DL, Burk RD, Boerwinkle E, Kaplan RC, Hu FB, Qi Q*. Healthful eating patterns, serum metabolite profile and risk of diabetes in a population-based prospective study of US Hispanics/Latinos. Diabetologia. 2022 Jul;65(7):1133-1144. PMID: 35357561

  • Chai JC, Chen GC, Yu B, Xing J, Li J, Khambaty T, Perreira KM, Perera MJ, Vidot DC, Castaneda SF, Selvin E, Rebholz CM, Daviglus ML, Cai J, Horn LV, Isasi CR, Sun Q, Hawkins M, Xue X, Boerwinkle E, Kaplan RC, Qi Q*. Serum Metabolomics of Incident Diabetes and Glycemic Changes in a Population with High Diabetes Burden: the Hispanic Community Health Study/Study of Latinos. Diabetes. 2022 Mar 16:db211056. PMID: 35293992

  • Qi Q*, Li J, Yu B, Moon JY, Chai JC, Merino J, Hu J, Ruiz-Canela M, Rebholz C, Wang Z, Usyk M, Chen GC, Porneala BC, Wang W, Nguyen NQ, Feofanova EV, Grove ML, Wang TJ, Gerszten RE, Dupuis J, Salas-Salvadó J, Bao W, Perkins DL, Daviglus ML, Thyagarajan B, Cai J, Wang T, Manson JE, Martínez-González MA, Selvin E, Rexrode KM, Clish CB, Hu FB, Meigs JB, Knight R, Burk RD, Boerwinkle E, Kaplan RC. Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies. Gut. 2022 Jun;71(6):1095-1105. PMID: 34127525 (*corresponding author)

  • Chen GC, Arthur R, Kamensky V, Chai JC, Yu B, Shadyab AH, Allison M, Sun Y, Saquib N, Wild RA, Bao W, Dannenberg AJ, Rohan TE, Kaplan RC, Wassertheil-Smoller S, Qi Q*. Body Fat Distribution, Cardiometabolic Traits, and Risk of Major Lower-Extremity Arterial Disease in Postmenopausal Women. Diabetes Care. 2022 Jan 1;45(1):222-231. PMID: 34732526

  • Wang Z, Usyk M, Vázquez-Baeza Y, Chen GC, Isasi CR, Williams-Nguyen JS, Hua S, McDonald D, Thyagarajan B, Daviglus ML, Cai J, North KE, Wang T, Knight R, Burk RD, Kaplan RC, Qi Q*. Microbial co-occurrence complicates associations of gut microbiome with US immigration, dietary intake and obesity. Genome Biol. 2021 Dec 10;22(1):336. PMID: 34893089

  • Chen GC, Arthur R, Mossavar-Rahmani Y, Xue X, Haring B, Shadyab AH, Allison MA, Liu S, Tinker LF, Saquib N, Coday M, Shikany JM, Neuhouser ML, Snetselaar LG, Van Horn L, Rohan TE, Wassertheil-Smoller S, Kaplan RC, Qi Q*. Adherence to Recommended Eating Patterns Is Associated with Lower Risk of Peripheral Arterial Disease: Results From the Women's Health Initiative. Hypertension. 2021 Aug;78(2):447-455. PMID: 34176290

  • Mei Z, Chen GC, Wang Z, Usyk M, Yu B, Baeza YV, Humphrey G, Benitez RS, Li J, Williams-Nguyen JS, Daviglus ML, Hou L, Cai J, Zheng Y, Knight R, Burk RD, Boerwinkle E, Kaplan RC, Qi Q*. Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of Latinos. Am J Clin Nutr. 2021 Jun 1;113(6):1503-1514. PMID: 33709132

  • Chen GC, Arthur R, Qin LQ, Chen LH, Mei Z, Zheng Y, Li Y, Wang T, Rohan TE, Qi Q*. Association of Oily and Nonoily Fish Consumption and Fish Oil Supplements with Incident Type 2 Diabetes: A Large Population-Based Prospective Study. Diabetes Care. 2021 Mar; 44(3):672-680. PMID: 33431419

  • Shan Z, Li Y, Baden MY, Bhupathiraju SN, Wang DD, Sun Q, Rexrode KM, Rimm EB, Qi L, Willett WC, Manson JE, Qi Q, Hu FB. Association Between Healthy Eating Patterns and Risk of Cardiovascular Disease. JAMA Intern Med. 2020 Aug 1;180(8):1090-1100. PMID: 32539102

  • Wang Z, Usyk M, Sollecito CC, Qiu Y, Williams-Nguyen J, Hua S, Gradissimo A, Wang T, Xue X, Kurland IJ, Ley K, Landay AL, Anastos K, Knight R, Kaplan RC, Burk RD, Qi Q*. Altered Gut Microbiota and Host Metabolite Profiles in HIV-infected Women. Clin Infect Dis. 2019 Nov 21. pii: ciz1117. doi: 10.1093/cid/ciz1117. [Epub ahead of print] PMID: 31748797

  • Chai JC, Deik AA, Hua S, Wang T, Hanna DB, Xue X, Haberlen SA, Shah SJ, Suh Y, Lazar JM, Gustafson D, Hodis HN, Landay AL, Anastos K, Post WS, Kaplan RC, Clish CB, Qi Q*. Association of Lipidomic Profiles With Progression of Carotid Artery Atherosclerosis in HIV Infection. JAMA Cardiol. 2019 Oct 23. doi: 10.1001/jamacardio.2019.4025. [Epub ahead of print] PMID: 31642867
  • Chen GC, Arthur R, Iyengar NM, Kamensky V, Xue X, Wassertheil-Smoller S, Allison MA, Shadyab AH, Wild RA, Sun Y, Banack HR, Chai JC, Wactawski-Wende J, Manson JE, Stefanick ML, Dannenberg AJ, Rohan TE, Qi Q.* Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index. Eur Heart J. 2019 Sep 7;40(34):2849-2855.  PMID: 31256194 
  • Moon JY, Louie TL, Jain D, Sofer T, Schurmann C, Below JE, Lai CQ, Aviles-Santa ML, Talavera GA, Smith CE, Petty LE, Bottinger EP, Chen YI, Taylor KD, Daviglus ML, Cai J, Wang T, Tucker KL, Ordovás JM, Hanis CL, Loos RJF, Schneiderman N, Rotter JI, Kaplan RC, Qi Q.* A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin A1c With Implications for Glycemic Status in U.S. Hispanics/Latinos. Diabetes Care. 2019 Jun 18. pii: dc190168. doi: 10.2337/dc19-0168. [Epub ahead of print] PMID: 31213470 
  • Kaplan RC, Wang Z, Usyk M, Sotres-Alvarez D, Daviglus ML, Schneiderman N, Talavera GA, Gellman MD, Thyagarajan B, Moon JY, Vázquez-Baeza Y, McDonald D, Williams-Nguyen JS, Wu MC, North KE, Shaffer J, Sollecito CC, Qi Q, Isasi CR, Wang T, Knight R, Burk RD.Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity. Genome Biol. 2019 Nov 1;20(1):219. doi: 10.1186/s13059-019-1831-z. PMID: 31672155
  • Zhao W, Wang X, Deik AA, Hanna DB, Wang T, Haberlen SA, Shah SJ, Lazar JM, Hodis HN, Landay AL, Yu B, Gustafson D, Anastos K, Post WS, Clish CB, Kaplan RC, Qi Q.* Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection. Circulation. 2019 Apr 23;139(17):2003-2011. PMID: 30759995 
  • Shan Z, Clish CB, Hua S, Scott JM, Hanna DB, Burk RD, Haberlen SA, Shah SJ, Margolick JB, Sears CL, Post WS, Landay AL, Lazar JM, Hodis HN, Anastos K, Kaplan RC, Qi Q. Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection. J Infect Dis. 2018 ;218(9):1474-1479.
  • Wang Z, Zolnik CP, Qiu Y, Usyk M, Wang T, Strickler HD, Isasi CR, Kaplan RC, Kurland IJ, Qi Q, Burk RD. Comparison of Fecal Collection Methods for Microbiome and Metabolomics Studies. Front Cell Infect Microbiol. 2018;8:301.
  • Moon JY, Wang T; Sofer T, North K, Isasi C, Cai J, Gellman M, Moncrieft A, Sotres-Alvarez D, Argos M, Kaplan RC, Qi Q. Objectively measured physical activity, sedentary behavior and genetic predisposition to obesity in US Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes 2017;66(12):3001-3012.
  • Qi Q, Strizich G, Merchant G, Sotres-Alvarez D, Buelna C, Castañeda SF, Gallo LC, Cai J, Gellman MD, Isasi CR, Moncrieft AE, Sanchez-Johnsen L, Schneiderman N, Kaplan RC. Objectively-measured sedentary time and cardiometabolic biomarkers in U.S. Hispanic/Latino adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Circulation. 2015 20;132(16):1560-9.
  • Qi Q, Downer MK, Kilpeläinen TO, et al. Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes. 2015 64(7):2467-76.
  • Qi Q, Chu AY, Kang JH, Huang J, Rose LM, Jensen MK, Liang L, Curhan GC, Pasquale LR, Wiggs JL, De Vivo I, Chan AT, Choi HK, Tamimi RM, Ridker PM, Hunter DJ, Willett WC, Rimm EB, Chasman DI, Hu FB, Qi L. Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies. BMJ. 2014 Mar 19;348:g1610. doi: 10.1136/bmj.g1610.PMID:24646652
  • Qi L, Qi Q, Prudente S, Mendonca C, Andreozzi F, di Pietro N, Sturma M, Novelli V, Mannino GC, Formoso G, Gervino EV, Hauser TH, Muehlschlegel JD, Niewczas MA, Krolewski AS, Biolo G, Pandolfi A, Rimm E, Sesti G, Trischitta V, Hu F, Doria A. Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. JAMA. 2013 28;310(8):821-8. PMID: 2398236
  • Qi Q, Xu M, Wu H, Liang L, Champagne CM, Bray GA, Sacks FM, Qi L. IRS1 Genotype Modulates Metabolic Syndrome Reversion in Response to 2-Year Weight-Loss Diet Intervention: The POUNDS LOST trial. Diabetes Care. 2013;36(11):3442-7. PMID: 24009303
  • Qi Q,Meigs JB, Rexrode KM, Hu FB, Qi L. Diabetes genetic predisposition score and cardiovascular complications among patients with type 2 diabetes. Diabetes care. 2013 36(3):737-739. PMID: 23069839.
  • Xu M, Qi Q, Liang J, Bray GA, Hu FB, Sacks FM, Qi L. Genetic determinant for amino acid metabolites and changes in body weight and insulin resistance in response to weight-loss diets: the preventing overweight using novel dietary strategies (POUNDS LOST) trial. Circulation. 2013127(12):1283-1289. PMID: 23446828.
  • Qi Q, Chu AY, Kang JH, Jensen MK, Curhan GC, Pasquale LR, Ridker PM, Hunter DJ, Willett WC, Rimm EB, Chasman DI, Hu FB, Qi L. Sugar-sweetened beverages and genetic risk of obesity. New England Journal of Medicine. 2012 367(15):1387-96. PMID: 22998338.
  • Qi Q, Li Y, Chomistek AK, Kang JH, Curhan GC, Pasquale LR, Willett WC, Rimm EB, Hu FB, Qi L. Television watching, leisure-time physical activity and the genetic predisposition in relation to body mass index in women and men. Circulation. 2012 126(15):1821-7. PMID: 22949498.
  • Qi Q, Workalemahu T, Zhang C, Hu FB, Qi L. Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes. European Heart Journal.2012 33(3):325-334. PMID: 21900290.
  • Qi Q, Menzaghi C, Smith S, Liang L, de Rekeneire N, Garcia ME, Lohman KK, Miljkovic I, Strotmeyer ES, Cummings SR, Kanaya AM, Tylavsky FA, Satterfield S, Ding J, Rimm EB, Trischitta V, Hu FB, Liu Y, Qi L. Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. Human Molecular Genetics.2012 21(21):4774-80. PMID: 22843503.
  • Qi Q, Liang L, Doria A, Hu FB, Qi L. Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts. Diabetes. 2012 61(3):745-752. PMID: 22315312.
  • Zhang X, Qi Q, Zhang C, Hu FB, Sacks FM, Qi L. FTO Genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the Pounds Lost Trial. Diabetes. 2012 61(11):3005-11. PMID: 22891219.
  • Qi Q, Bray GA, Smith SR, Hu FB, Sacks FM, Qi L. Insulin receptor substrate 1 gene variation modifies insulin resistance response to weight-loss diets in a 2-year randomized trial: the Preventing Overweight Using Novel Dietary Strategies (Pounds Lost) Trial. Circulation. 2011 124(5):563-571. PMID: 22509365.

 

Complete List of Published Work in MyBibliography:

http://www.ncbi.nlm.nih.gov/sites/myncbi/qibin.qi.1/bibliography/48085574/public/