Areas of Research: Primary research areas are focused on identifying distinctive immunologic and molecular genetic diagnostic and prognostic markers of hematologic neoplasms.

Professional Interests: Pathological diagnosis of hematopoietic abnormalities, including mature and immature lymphoma/leukemia; myeloproliferative/dysplastic myeloid neoplasms, plasma cell proliferative disorder and other hematological related abnormalities using flow cytometry, immunohistochemistry, cytogentic/FISH and molecular diagnostic tools.

Selected Recent Publications:

 1.    Yanghua Wang¹, Adam Gersten¹, Susana Moleirinho^2,3, Frank J. Gunn-Moore², Paul A. Reynolds³, Michael B. Prystowsky¹  Fibroblasts in Head Neck Squamous Cell Carcinoma Associated with Peri-neural Invasion Have High Level Nuclear Yap Expression  Academic Pathology, 20152.    

2.    Jose G.M. Arango, Shlomit Goldberg-Stein, Yanhua Wang Extranodal Rosai-Dorfman disease: Clinico-pathologic series of thirteen cases and review of the literature American Journal of Clinical Pathology, 2016; 0:1-11

3.     Monica Zell,*, Amer Assal,*, Olga Derman, Noah Kornblum, Ramakrishna Battini, Yanhua Wang, Deepa M. Narasimhulu, Ioannis Mantzaris, Aditi Shastri, Amit Verma, Hilda Ye, IraBraunschweig, Murali Janakiram   Adult T-Cell leukemia/lymphoma in the Caribbean cohort is adistinct clinical entity with dismal response to conventional chemotherapy Oncotarget, June 2016 DOI: 10.18632/oncotarget.10223

4.     Goel S, Hall J, Pradhan K, Hirsch C, Przychodzen B, Shastri A, Mantzaris I, Janakiram M, Battini R, Kornblum N, Derman O, Gritsman K, Al-Hafidh J, Wang Y, Halmos B, Steidl U, Maciejewski JP, Braunschweig I, Verma A. High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort. Leukemia. 2016 Apr 29. doi: 10.1038/leu.2016.74. [Epub ahead of print]

5.     Monica Zell, Amer Assal, Olga Derman, Noah Kornblum, Ramakrishna Battini, Yanhua Wang, Deepa M. Narasimhulu, Ioannis Mantzaris, Aditi Shastri, Amit Verma, Hilda Ye, Ira Braunschweig, Murali Janakiram   Adult T-Cell leukemia/lymphoma in the Caribbean cohort is a distinct clinical entity with dismal response to conventional chemotherapy.  Oncotarget, Advance Publications 2016

6.      Yanhua Wang, Samer Khader, Yonatan Mehlman, Yungtai Lo, Joseph Albanese, Howard Ratech Loss of αII and βIII Spectrin Isoforms in Body Fluids is Associated with Metastasis. Advances in Cytology & Pathology, Volume 2 Issue 1 – 2017

7.     Etan Marks, Yang Shi, Yanhua Wang CD117 (KIT) Is A Useful Marker in The Diagnosis of Plasmablastic Plasma Cell Myeloma, Histopathology, 2017, DOI: 10.1111/his.13196

8.     Murali Janakiram , Amit Verma, Yanhua Wang, Anjali Budhathoki, Jaime Suarez Londono, Irina Murakhovskaya, Ira Braunschweig & Caterina P.Minniti  Accelerated leukemic transformation after haploidentical transplantation for hydroxyurea-treated sickle cell disease, Leukemia & Lymphoma, DOI: 10.1080/10428194.2017.1324158

9.     Zhonghua Li, M.D., Ph.D., John G. Pizzolo, B.S., Yanhua Wang, M.D., Ph.D.Utility of Cytocentrifugation Slides in the Flow Cytometry Laboratory: a Single Institution experience, Clinical Pathology Diangosis,  Journal of Hematopathology, online, 2017

10.  Michael J. Licata, MD¹, Murali Janakiram, MD², Yanan Fang, MD¹, Urvi A. Shah, MD², Amit Verma, MD² and Yanhua Wang, MD Diagnostic Challenges of Western Adult T-Cell Leukemia/Lymphoma with Unusual Clinical Presentation - Clinical, Histological and Immunophenotypic Analysis, Leukemia & Lymphoma, 2018 VOL. 59, NO. 5, 1188–1194 https://doi.org/10.1080/10428194.2017.1365862

11.  Evan Himchak, Etan Marks, Yang Shi, Yanhua Wang, Did I miss one? Discovering Hidden Co-existing Hematological with Non-Hematological Malignancies, A Single Institutional Review of 100 Collision Tumors, Int J Surg Pathol. 2018 Jan 1:1066896917752862. doi: 10.1177/1066896917752862. [Epub ahead of print]

12.  Jesus Anampa, Tamanna Haque, Irina Murakhovskaya, Yanhua Wang, Kimo Bachiashvili, Cristian Papazoglu, Kith Pradhan, Ulrich G. Steidl, Joseph A. Sparano, Amit Verma    Macrocytosis And Dysplastic Anemia Is Associated With The Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib In Metastatic Breast Cancer, Haematologica , Published Ahead of Print on November 30, 2017, as doi:10.3324/haematol.2017.181941

13.  Shaomin Hu, James Szymanski, Zeina Khairy, Yungtai Lo, Yanhua Wang Breast pathology and mammography BI-RADS category correlation study – A single institute experience Annals of Diagnostic Pathology 35 (2018) 11-15

14.  Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, Bartenstein M, Goel S, Mantzaris I, Shastri A, Derman O, Binder A, Gritsman K, Kornblum N, Braunschweig I, Bhagat C, Hall J, Graber A, Ratner L, Wang Y, Ogawa S, Verma A, Ye BH, Janakiram M. North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies. Blood. 2018 Oct 4;132(14):1507-1518. doi: 10.1182/blood-2018-01-824607. Epub 2018 Aug 13.