Solomon L. Moshé, M.D., is the Charles Frost Chair in Neurosurgery and Neurology, and Professor of Neurology, Neuroscience, and Pediatrics at the Albert Einstein College of Medicine/Montefiore Medical Center in the Bronx, New York. He is also the Vice Chair of the Saul R. Korey Department of Neurology, Director of the Isabelle Rapin Child Neurology Division and Director of Clinical Neurophysiology. His area of expertise is in epilepsy and related disorders.

Since 1979, his research has focused on understanding the mechanisms underlying age and sex-related differences in epilepsy in humans and animal models.  Current research interests include studies on the role of subcortical circuitries involved in the control of seizures as a function of age and sex; the consequences of seizures on the developing brain and the development of models of catastrophic epilepsies. His laboratory has patented a model of infantile spasms that can be used to identify novel treatments. He is co principal investigator of a Center Without Walls grant on interdisciplinary research aimed at accelerating the development of disease modifying or prevention therapies for epilepsy following traumatic brain injuries. He is also involved in a large multicenter study examining the consequences of prolonged febrile seizures.  He has over 600 publications as well as He has over 600 publications as well over 35 books and monographs.

over 35 books and monographs.

 He has served as President of the International League Against Epilepsy (2009-2013), the American Epilepsy Society (2000-2001), the American Clinical Neurophysiology Society (1996-1997) and the Eastern Association of EEGers (1992-1994). He is the recipient of many awards and honors, including the Teacher-Investigator Development Award from NINDS; the 1995 Jacob Javits Neuroscience Investigator Award from NINDS; the 1984 Michael Prize for Achievements in Epilepsy Research; the 1990 American Epilepsy Society Research Award; the 1999 Ambassador for Epilepsy Award from the International League Against Epilepsy; the 2005 Gloor Award from the American Clinical Neurophysiology Society; the 2007 J.E. Purkyne Honorary Medal in Biomedical Research by the Czech Academy of Sciences; the 2008 Mentor of the Year Award from Albert Einstein College of Medicine; the 2010 Global and Awareness Award from CURE, Citizens United for Research in Epilepsy; the First 2012 Saul R. Korey Award in Translational Science and Medicine, Albert Einstein College of Medicine and the 2017 Bernard Sachs Award from the Child Neurology Society, and the 2023 Lifetime Achievement Award from the International League against Epilepsy.

He has been asked to deliver over 50 several keynote lectures.

Clinical Focus:

Dr. Moshé focuses on helping people with epilepsy and related conditions with a special emphasis on children and adolescents.

Research focus

Dr Moshé has focused on translational research to understand the mechanisms underlying age and sex-related differences in epilepsy in humans and animal models. The main goals are to develop individualized treatments today and to prevent and cure epilepsy tomorrow. Current projects include the development of effective means to predict and treat epilepsy after traumatic brain injury and the development of specialized treatments for infants and children with epilepsy.

1.  Katsarou A, Moshé SL, Galanopoulou AS.  Interneuronopathies and their role in early life epilepsies and neurodevelopmental disorders.   Epilepsia Open 3: 284-306 (2017). PMID: 29062978
2. Moshe SL.  The 2017 Sachs lecture: Kindling knowledge in Epilepsy.  Pediatric Neurology 85: 5-12 (2018).  PMID: 29958806
3. Saletti PG, Ali I, Casillas-Espinonsa PM, Semple BD, Lisgaras C, Moshe SL, Galanopoulou AS. In search of antiepileptogenic treatments for post-traumatic epilepsy.  Neurobiology of Disease 123: 86-99 (2019).  PMID: 29936231
4. Correa DJ, Kwon C, Connors S, Fureman B, Whittemore V, Jette N, Mathern G and Moshe SL.   For the EpiBioS4RX Public Engagement Core.   Applying participatory action research in traumatic brain injury studies to prevent post-traumatic epilepsy.   Neurobiology of Disease 123: 137-144 (2019).  PMID: 30031158
5. Molinero I, Galanopoulou AS and Moshe SL.   Rodent models: Where it all started with these “truths”.   European Journal of Paediatric Neurology 61-65 (2020) PMID: 31875833
6. Ozlem A, Briggs S, Mowrey W, Moshe SL, Galanopoulou AS   Antiepiletogenic effects of rapamycin in a model of infantile spasms due to structural lesions.   Epilepsia, 62,1985-1999, (2021) PMID: 34212374

7. Zuberi S, Wirrell E, Yozawitz E, Wilmshurst J, Specchi N, Riney K, Pressler R, Auvin S, Samia P, Hirsch E, Galicchio S, Triki C, Snead O, Wiebe S, Cross H, Tinuper P, Scheffer I, Perucca E and Moshe SL.   ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions.  Epilepsia, 63, 1349-1397 (2022) PMID: 35503712

8. Hirsch E, French J, Scheffer I, Bogacz A, Alsaadi T, Sperling M, Abdulla F, Zuberi S, Trinka E, Specchio N, Somerville E, Samia P, Riney K, Nabbout R, Jain S, Wilmshurst J, Auvin S, Wiebe S, Perucca E, Moshe SL, Tinuper P and Wirrell E.  ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions.  Epilepsia, 63, 1475-1499 (2022) PMID: 35503716

9. Specchio N, Wirrell E, Scheffer I, Nabbout R, Riney K, Samia P, Guerreiro M, Gwer S, Zuberi S, Wilmshurst J, Yozawitz E, Pressler R, Hirsch E, Wiebe S, Cross H, Perucca E, Moshe SL, Tinuper P and Auvin S.  International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.  Epilepsia, 63, 1398-1442 (2022) PMID: 35503717

10.  Riney K, Bogacz A, Somerville E, Hirsch E, Nabbout R, Scheffer I, Zuberi S, Alsaadi T, Jain S, French J, Specchio N, Trinka E, Wiebe S, Auvin S, Cabral-Lin L, Naiddo A, Perucca E, Moshe SL, Wirrell E and Tinuper P.  International League Againist Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions.   Epilespia, 63, 1443-1474 (2022) PMID: 35503725

11. Wirrell E, Nabbout R, Scheffer I, Alsaadi T, Bogacz A, French J, Hirsch E, Jain S, Kaneko S, Riney K, Samia P, Snead O, Somerville E, Specchio N, Trinka E, Zuberi S, Balestrini S, Wiebe S, Cross H, Perucca E, Moshe SL and Tinuper P.   Methodology for classification and definition of epilepsy syndromes with list of syndroms: Report of the ILAE Task Force on Nosology and Definitions.   Epilepsia, 63, 1333-1348 (2022) PMID: 35503715

12. Saletti P, Casillas-Espinosa P, Lisgaras C, Mowrey W, Li Q, Liu W, Brady R, Ali I, Silva J, Yamakawa G, Hudson M, Li C, Braine E, Coles L, Cloyd J, Shultz S, Moshé SL, O’Brien T, Galanopoulou AS for the EpiBioS4RX Group.    TAU phosphorylation patterns in the rat cerebral cortex after traumatic brain injury and sodium selenate effects:  An EpiBioS4Rx Project 2 study.   Journal of Neurotrauma pgs 1-22, (2023.)  PMID: 36950806

13. Saletti P, Mowrey W, Liu W, Li Q, McCullough J, Aniceto R, Lin I-H, Eklund M, Casillas-Espinosa P, Ali I, Santana-Gomez C, Coles L, Shultz S, Jones N, Staba R, O’Brien T, Moshé SL, Agoston D, Galanopoulou AS for the EpiBioS4RX Study Group.     Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam.   Epilepsia Open pgs. 586-608 (2023) PMID: 37026764

14. Coles L, Saletti P, Lisgaras C, Casillas-Espinosa P, Liu W, Li Q, Jones N, Shultz S, Ali I, Brady R, Yamakawa G, Hudson M, Silva J, Braine E, Mishra U, Cloyd J, O’Brien T, Moshé SL, Galanopoulou AS for the EpiBioS4RX Study Group.   Levetiracetam Pharmacokinetics and Brain Uptake in a Lateral Fluid Percussion Injury Rat Model.   Journal of Pharmacology and Experimental Therapeutics pgs 1-30, (2023).  PMID: 37316328