Publications Kim G, Karadal-Ferrena B, Qin J, Sharma VP, Oktay IS, Lin Y, et al. Racial disparity in tumor microenvironment and distant recurrence in residual breast cancer after neoadjuvant chemotherapy. NPJ Breast Cancer. 2023;9(1):52. Genna A, Duran CL, Entenberg D, Condeelis JS, Cox D. Macrophages Promote Tumor Cell Extravasation across an Endothelial Barrier through Thin Membranous Connections. Cancers (Basel). 2023;15(7). Genna A, Duran CL, Entenberg D, Condeelis J, Cox D. Macrophages Promote Tumor Cell Extravasation across an Endothelial Barrier through Thin Membranous Connections. bioRxiv. 2023. Friedman-DeLuca M, Patel PP, Karadal-Ferrena B, Barth ND, Duran CL, Ye X, et al. Tracking Tumor Cell Dissemination from Lung Metastases Using Photoconversion. J Vis Exp. 2023(197). Entenberg D, Oktay MH, Condeelis JS. Intravital imaging to study cancer progression and metastasis. Nat Rev Cancer. 2023;23(1):25-42. Duran CL, Karagiannis GS, Chen X, Sharma VP, Entenberg D, Condeelis JS, et al. Cooperative NF-kappaB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer. Breast Cancer Res. 2023;25(1):37. Ye X, Oktay MH, Xue X, Rohan TE, Ginter PS, D'Alfonso T, et al. Combining TMEM Doorway Score and Mena(Calc) Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2- Breast Cancer Patients. Cancers (Basel). 2022;14(9). Selvanesan BC, Chandra D, Quispe-Tintaya W, Jahangir A, Patel A, Meena K, et al. Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice. Sci Transl Med. 2022;14(637):eabc1600. Rodriguez-Tirado C, Entenberg D, Li J, Qian BZ, Condeelis JS, Pollard JW. Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice. Cancers (Basel). 2022;14(17). Linder S, Cervero P, Eddy R, Condeelis J. Mechanisms and roles of podosomes and invadopodia. Nat Rev Mol Cell Biol. 2022. Kim G, Pastoriza JM, Qin J, Lin J, Karagiannis GS, Condeelis JS, et al. Racial disparity in distant recurrence-free survival in patients with localized breast cancer: A pooled analysis of National Surgical Adjuvant Breast and Bowel Project trials. Cancer. 2022;128(14):2728-35. Karagiannis GS, Bianchi A, Sanchez LR, Ambadipudi K, Cui MH, Anampa JM, et al. Assessment of MRI to estimate metastatic dissemination risk and prometastatic effects of chemotherapy. NPJ Breast Cancer. 2022;8(1):101. Du W, Adkisson C, Ye X, Duran CL, Chellakkan Selvanesan B, Gravekamp C, et al. SWIP-a stabilized window for intravital imaging of the murine pancreas. Open Biol J. 2022;12(6):210273. Borriello L, Coste A, Traub B, Sharma VP, Karagiannis GS, Lin Y, et al. Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells. Nat Commun. 2022;13(1):626. Sharma VP, Williams J, Leung E, Sanders J, Eddy R, Castracane J, et al. SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast Motility of Breast Carcinoma Cells in Fibrillar ECM Microenvironment. Cells. 2021;10(6). Sharma VP, Tang B, Wang Y, Duran CL, Karagiannis GS, Xue EA, et al. Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination. Nat Commun. 2021;12(1):7300. Duran CL, Borriello L, Karagiannis GS, Entenberg D, Oktay MH, Condeelis JS. Targeting Tie2 in the Tumor Microenvironment: From Angiogenesis to Dissemination. Cancers (Basel). 2021;13(22). Borriello L, Coste A, Sharma VP, Karagiannis GS, Lin Y, Wang Y, et al. Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells. bioRxiv. 2021:2021.02.04.429798. Borriello L, Condeelis J, Entenberg D, Oktay MH. Breast Cancer Cell Re-Dissemination from Lung Metastases-A Mechanism for Enhancing Metastatic Burden. J Clin Med. 2021;10(11). Sharma VP, Williams J, Leung E, Sanders J, Eddy R, Castracane J, et al. SUN-MKL1 crosstalk regulates nuclear deformation and fast motility of breast carcinoma cells in fibrillar ECM micro-environment. bioRxiv. 2020:2020.11.24.396390. Sharma VP, Tang B, Wang Y, Karagiannis GS, Xue EA, Entenberg D, et al. Live imaging of breast tumors shows macrophage-dependent induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination. bioRxiv. 2020:2020.09.18.303388. Kim G, Pastoriza JM, Condeelis JS, Sparano JA, Filippou PS, Karagiannis GS, et al. The Contribution of Race to Breast Tumor Microenvironment Composition and Disease Progression. Front Oncol. 2020;10:1022. Entenberg D, Oktay MH, D'Alfonso T, Ginter PS, Robinson BD, Xue X, et al. Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM, a Prognostic Biomarker for Metastasis. Cancers (Basel). 2020;12(4). Entenberg D, Oktay MH, Condeelis J. Intravital Imaging of Cancer Cell Migration In Vivo. In: Barroso M, Intes X, editors. Imaging from Cells to Animals In Vivo. Series in cellular and clinical imaging: CRC Press; 2020. p. 183. Coste A, Oktay MH, Condeelis JS, Entenberg D. Intravital Imaging Techniques for Biomedical and Clinical Research. Cytometry A. 2020;97(5):448-57. Coste A, Karagiannis GS, Wang Y, Xue EA, Lin Y, Skobe M, et al. Hematogenous Dissemination of Breast Cancer Cells From Lymph Nodes Is Mediated by Tumor MicroEnvironment of Metastasis Doorways. Front Oncol. 2020;10:571100. Borriello L, Karagiannis GS, Duran CL, Coste A, Oktay MH, Entenberg D, et al. The role of the tumor microenvironment in tumor cell intravasation and dissemination. Eur J Cell Biol. 2020;99(6):151098. Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, et al. A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nat Cancer. 2020;1(3):315-28. Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, et al. Optogenetic control of cofilin and alphaTAT in living cells using Z-lock. Nat Chem Biol. 2019;15(12):1183-90. Sanchez LR, Borriello L, Entenberg D, Condeelis JS, Oktay MH, Karagiannis GS. The emerging roles of macrophages in cancer metastasis and response to chemotherapy. J Leukoc Biol. 2019;106(2):259-74. Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha VV, Connolly D, et al. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene. 2019;38(30):5839-59. Liu X, Taftaf R, Kawaguchi M, Chang YF, Chen W, Entenberg D, et al. Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models. Cancer Discov. 2019;9(1):96-113. Karagiannis GS, Pastoriza JM, Borriello L, Jafari R, Coste A, Condeelis JS, et al. Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis. J Vis Exp. 2019(148). Karagiannis GS, Condeelis JS, Oktay MH. Chemotherapy-Induced Metastasis: Molecular Mechanisms, Clinical Manifestations, Therapeutic Interventions. Cancer Res. 2019;79(18):4567-76. Ginter PS, Karagiannis GS, Entenberg D, Lin Y, Condeelis J, Jones JG, et al. Tumor Microenvironment of Metastasis (TMEM) Doorways Are Restricted to the Blood Vessel Endothelium in Both Primary Breast Cancers and Their Lymph Node Metastases. Cancers (Basel). 2019;11(10):1507. Anampa J, Xue X, Oh S, Kornblum N, Sadan S, Oktay M, et al. Abstract P6-18-22: Phase Ib study of rebastinib plus antitubulin therapy with paclitaxel (P) or eribulin (E) in patients with HER2-negative metastatic breast cancer (MBC). AACR; 2019. Pastoriza JM, Karagiannis GS, Lin J, Lanjewar S, Entenberg D, Condeelis JS, et al. Black race and distant recurrence after neoadjuvant or adjuvant chemotherapy in breast cancer. Clin Exp Metastasis. 2018. Norwood Toro LE, Wang Y, Condeelis JS, Jones JG, Backer JM, Bresnick AR. Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis. Exp Cell Res. 2018;370(2):273-82. Nobre AR, Entenberg D, Wang Y, Condeelis J, Aguirre-Ghiso JA. The Different Routes to Metastasis via Hypoxia-Regulated Programs. Trends Cell Biol. 2018;28(11):941-56. Meirson T, Genna A, Lukic N, Makhnii T, Alter J, Sharma VP, et al. Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors. Oncotarget. 2018;9(31):22158-83. Linde N, Casanova-Acebes M, Sosa MS, Mortha A, Rahman A, Farias E, et al. Macrophages orchestrate breast cancer early dissemination and metastasis. Nat Commun. 2018;9(1):21. Karagiannis GS, Condeelis JS, Oktay MH. Chemotherapy-induced metastasis: mechanisms and translational opportunities. Clin Exp Metastasis. 2018;35(4):269-84. Genna A, Lapetina S, Lukic N, Twafra S, Meirson T, Sharma VP, et al. Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells. J Cell Biol. 2018;217(1):375-95. Entenberg D, Voiculescu S, Guo P, Borriello L, Wang Y, Karagiannis GS, et al. A permanent window for the murine lung enables high-resolution imaging of cancer metastasis. Nat Methods. 2018;15(1):73-80. Cabrera RM, Mao SPH, Surve CR, Condeelis JS, Segall JE. A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration. Breast Cancer Res. 2018;20(1):24. Butt L, Entenberg D, Hemachandra LPM, Strohmayer M, Keely P, Aguirre-Ghiso J, et al. Development of microfluidic-based cell collection devices for in vitro and in vivo use. Microbes and infection / Institut Pasteur. 2018. Arwert EN, Harney AS, Entenberg D, Wang Y, Sahai E, Pollard JW, et al. A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation. Cell Rep. 2018;23(5):1239-48. Scheele C, Herrmann D, Yamashita E, Celso CL, Jenne CN, Oktay MH, et al. Multiphoton intravital microscopy of rodents. Nat Rev Methods Primers. 2022;2(1):1-26. Borriello L, Traub B, Coste A, Oktay MH, Entenberg D. A Permanent Window for Investigating Cancer Metastasis to the Lung. J Vis Exp. 2021(173). Asiry S, Kim G, Filippou PS, Sanchez LR, Entenberg D, Marks DK, et al. The Cancer Cell Dissemination Machinery as an Immunosuppressive Niche: A New Obstacle Towards the Era of Cancer Immunotherapy. Front Immunol. 2021;12:654877. Christin JR, Wang, C., Chung, C.Y., Liu, Y., Dravis, C., Tang, W, Oktay, M.H., Wahl, G. M., Guo W. . Stem cell determinant SOX9 promotes lineage plasticity and progression in basal-like breast cancer. Cell Rep. 2020.
