Núcleo de biomarcadores y tecnologías avanzadas

The Biomarkers & Advanced Technologies Core provides an extensive array of support services ranging from the measurement of a wide range of biomarkers to the molecular quantification of HIV DNA and RNA to the development and implementation of specialized high-throughput assays focused on supporting basic, translational, clinical, and epidemiological ERC-CFAR investigators engaged in the ERC-CFAR mission to prevent, treat, and eradicate HIV-1 infection.

Servicios

Acceder a los Servicios

Analysis of sera, plasma, CSF, cervical-vaginal lavage fluid, tissue culture supernatants and cell lysates from humans, rodents and macaques for quantification of biomarkers such as cytokines/chemokines, growth factors, and other mediators using high-throughput multiplex platforms and focused ELISAs
Production of large quantities of purified proteins in eukaryotic or prokaryotic expression systems for in vivo studies requiring large quantities of biological proteins including specific cytokines, chemokines and monoclonal antibodies
Full support for a wide range of molecular assays for evaluating HIV infection including RT-qPCR and digital PCR for quantification of HIV viral RNA and DNA and for the quantification of the latent HIV-infected cell population
Access to the Case Western CFAR Virology, Next Generation Sequencing and Imaging Core for support for studies requiring deep HIV sequencing and mutational analysis in laboratory and clinical isolates