Of Mice and Metastasis

The Scientist quotes John Condeelis, Ph.D., about his lab’s new methods of studying animal models of cancer metastasis. Dr. Condeelis is professor and co-chair of anatomy and structural biology, co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer

An editorial highlights research by Drs. Maja Oktay, George Karagiannis, and John Condeelis on the mechanism by which some breast cancer tumor cells resist chemotherapy and go on to metastasize. Dr. Oktay is professor of pathology; Dr. Condeelis is the Judith & Burton P. Resnick Chair in Translational Research and professor and co-chair of anatomy and structural biology; Dr. Karagiannis is a postdoctoral fellow


Chemotherapy before breast cancer surgery might fuel metastasis

STAT interviews John Condeelis, Ph.D., about his role in a recent study that linked preoperative chemotherapy with activating the microenvironment of metastasis in breast cancer. Dr. Condeelis is professor and co-chair of anatomy and structural biology and co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


WABC-TV interviews John Condeelis, M.D., about his imaging research that is helping to explain how cancer spreads from the primary tumor. Dr. Condeelis and his team found that normal immune cells, called macrophages, aid the tumor cells in cancer metastasis by directing the tumor cells toward blood vessels. By better understanding this process at the patient level, doctors can more accurately assess which patients need aggressive treatments and which patients can be spared those treatments. Dr. Condeelis is professor and co-chair of anatomy and structural biology and co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


Nature highlights research by John Condeelis, Ph.D., that uses intravital imaging to reveal how breast cancer cells spread from the primary tumor.  Dr. Condeelis’s lab found that three types of cells – a macrophage (an immune cell), a tumor cell (primed for invasion) and an epithelial cell (which form the outer skin of blood vessles) form a type of “pump” to push tumor cells into the bloodstream. From there, they can travel to distant sites in the body. Dr. Condeelis is professor and co-chair of anatomy and structural biology and co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


The New York Times, Science Times, interviews John S. Condeelis, Ph.D., on Einstein research into technologies that allow scientists to watch cells, including cancer cells, move. Dr. Condeelis is professor and co-chair of anatomy and structural biology and co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


Los Angeles Times features comments by John S. Condeelis, Ph.D., on the first marker that could reliably predict metastatic breast cancer. Dr. Condeelis’ earlier work has shown that the co-mingling of three cell types can predict whether localized breast cancer will spread throughout the body. Now, a collaborative study with NewYork-Presbyterian Hospital/Weill Cornell Medical Center and MIT, has produced a test for metastasis. Dr. Condeelis is professor and co-chair of anatomy and structural biology and co-director of the Gruss Lipper Biophotonics Center, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.

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NCI Cancer Bulletin interviews John Condeelis, Ph.D., about advanced imaging techniques developed by researchers in Einstein's Gruss Lipper Biophotonics Center that allow cancer cells to be viewed for weeks. Dr. Condeelis is co-director of the Biophotonics Center and co-chair of anatomy and structural biology, and the Judith and Burton P. Resnick Chair in Translational Research at Einstein.


Washington Post, U.S. News & World Report, and others report on a new protein marker relevant to the spread of cancer. The marker, detailed in a study published in Developmental Cell, was discovered by Einstein and MIT researchers. The Einstein team was lead by Dr. John Condeelis, co-chair of anatomy and structural biology.

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