Seeking Rejuvenation Factors in Blood

Seeking Rejuvenation Factors in Blood

For the last few decades, scientists studying aging have carried out heterochronic parabiosis—surgically creating a circulatory system shared by two animals of different ages. Those studies indicate that the blood of young animals contains rejuvenation factors (known as anti-geronic factors) that restore youthful characteristics to cells and tissues of older animals. Identifying these factors and finding how they exert their effects could lead to drugs for warding off age-associated diseases in people. The National Institute on Aging has awarded Yousin Suh, Ph.D., a four-year, $1.94 million grant to identify circulating anti-geronic factors using cultured cells and animal models of heterochronic parabiosis. Dr. Suh is professor of genetics, of ophthalmology & visual sciences, and of medicine.(1R01AG057433)