Department Chair

Ulrich G. Steidl, M.D., Ph.D.

Ulrich G. Steidl, M.D., Ph.D.

Professor, Department of Cell Biology

Professor, Department of Oncology

Professor, Department of Medicine

Chair Department of Cell Biology

Edward P. Evans Endowed Professor for Myelodysplastic Syndromes

Deputy Director, and Associate Director for Basic Science Montefiore Einstein Comprehensive Cancer Center

Co-Director, Blood Cancer Institute

Interim Director, The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research

718.430.3437

Areas of Research: hematopoiesis; stem cell origin of cancer; leukemia; AML; MDS; hematopoietic stem cells (HSC); (pre)leukemic stem cells (LSC); transcription dynamics; molecular noise; epigenetics; targeted therapy; drug development; translational computational biology

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All Faculty

Julio A. Aguirre-Ghiso, Ph.D.

Julio A. Aguirre-Ghiso, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Oncology (Medical Oncology)

Professor, Department of Medicine (Oncology & Hematology)

Rose C. Falkenstein Chair in Cancer Research

Director, Institute for Cancer Dormancy and Tumor Microenvironment

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Tumor Microenvironment & Metastasis Program

718.678.1246

Areas of Research: Metastasis biology Cancer cell dormancy Signal transduction Extracellular matrix Innate immune cell function tumor and normal organ microenvironment

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Barbara K. Birshtein, Ph.D.

Barbara K. Birshtein, Ph.D.

Professor Emerita, Department of Cell Biology

Director of Training Grant Support Programs

Scientific Director, Training & Educational Grants Office

718.430.2291

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Eric E. Bouhassira, Ph.D.

Eric E. Bouhassira, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Medicine (Oncology & Hematology)

Professor, Department of Oncology (Hematology)

Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine

718.430.2188

Areas of Research: Pluripotent stem cells, erythroid differentiation, red blood cells, gene therapy, hemoglobinopathies, genome modification, TTP, hemophilia A

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John S. Condeelis, Ph.D.

John S. Condeelis, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Surgery

The Judith and Burton P. Resnick Chair in Translational Research

Chair Emeritus Department of Anatomy & Structural Biology

Co-Director, Integrated Imaging Program

Scientific Director, Analytical Imaging Facility

Director, Integrated Imaging Program for Cancer Research

718.430.2718

Areas of Research: Interests are in optical physics, cell biology and biophysics, and cancer biology. Applications of interests are in development of the multiphoton imaging technology used to identify dissemination microenvironments in metastatic tumors.

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Winfried Edelmann, Ph.D.

Winfried Edelmann, Ph.D.

Professor, Department of Cell Biology

Professor, Department of Genetics

The Joseph and Gertrud Buchler Chair in Transgenic Medicine

Faculty Supervisor, Gene Modification Gene Targeting and Transgenic Facilities

718.678.1086

Areas of Research: We are studying the roles of DNA mismatch repair (MMR) in genome maintenance and tumor suppression in mouse models of human cancer and the role of MMR in the response of intestinal cancer stem cells to anticancer treatment.

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Dmitry Fyodorov, Ph.D.

Dmitry Fyodorov, Ph.D.

718.430.4021

Areas of Research: Packaging DNA into chromatin maintains & compartmentalizes the genome. We examine how nucleosome remodeling factors, histone chaperones & modifying enzymes establish chromatin compartments and shape gene expression patterns.

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Matthew J. Gamble, Ph.D.

Matthew J. Gamble, Ph.D.

718.430.2942

Areas of Research: Histone variant macroH2A; Cancer; Cellular senescence; Chromatin structure and function; Transcription; Splicing; Senescence-associated secretory phenotype; Endoplasmic reticulum stress responses; Poly(ADP-ribose) polymerase

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Kira Gritsman, M.D., Ph.D.

Kira Gritsman, M.D., Ph.D.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Cell Biology

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Stem Cell & Cancer Biology Program

Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research

929.246.6707

Areas of Research: roles of signaling pathways in hematopoietic stem cell self-renewal and differentiation, leukemic stem cells, targeting signaling pathways in hematologic malignancies

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Wenjun Guo, Ph.D.

Wenjun Guo, Ph.D.

718.678.1276

Areas of Research: Cancer stem cells, mammary stem cells, tumor immune microenvironment, immunotherapy, cellular plasticity, metastasis, therapeutic resistance

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Rhoda E. Hirsch, Ph.D.

Rhoda E. Hirsch, Ph.D.

Professor Emerita, Department of Oncology (Hematology)

Professor Emerita, Department of Medicine (Oncology & Hematology)

Professor Emerita, Department of Cell Biology

718.430.3604

Areas of Research: Hemoglobinopathies (e.g., HbE/beta-thalassemia, sickle cell disease, HbC Disease) & pathophysiological mechanisms underlying these morbid & often fatal diseases with a focus on therapeutic design. Acellular giant Hb as a HBOC

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Keisuke Ito, M.D., Ph.D.

Keisuke Ito, M.D., Ph.D.

Professor, Department of Cell Biology

Professor, Department of Medicine

Professor, Department of Oncology (Medical Oncology)

Director of Scientific Resources of the Stem Cell Institute

718.678.1278

Areas of Research: Hematopoietic stem cells (HSCs) and Stem cell fate; Myelodysplastic syndrome (MDS) and hematological malignancies; Stem cell metabolisms and epigenetics; Bone marrow microenvironment; Sickle cell disease and vaso-occlusion

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Margaret Kielian, Ph.D.

Margaret Kielian, Ph.D.

Professor, Department of Cell Biology

Samuel H. Golding Chair in Microbiology

718.430.3638

Areas of Research: Areas of research: Virus entry into host cells and virus membrane fusion; virus assembly and exit; virus genome encapsidation; virus protein structure and function; virus cell-to-cell transmission

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Richard N. Kitsis, M.D.

Richard N. Kitsis, M.D.

Professor, Department of Medicine (Cardiology)

Professor, Department of Cell Biology

The Dr. Gerald and Myra Dorros Chair in Cardiovascular Disease

Director, Wilf Family Cardiovascular Research Institute

718.430.2609

Areas of Research: Cell Death and Mitochondrial Biology: Fundamental Mechanisms and Roles in Human Disease

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Lindsay M. LaFave, Ph.D.

Lindsay M. LaFave, Ph.D.

Assistant Professor, Department of Cell Biology

718.430.2090

Areas of Research: lung cancer, lung stem cells, cancer predisposition, chromatin biology, single-cell epigenomics, chromatin plasticity, intratumoral heterogeneity, lung adenocarcinoma, gene regulatory networks, spatial profiling, transcription factor biology

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Maria Marianovich, Ph.D.

Maria Marianovich, Ph.D.

Assistant Professor, Department of Cell Biology

718.678.1066

Areas of Research: Hematopoietic stem cell and cancer stem cell microenvironment. Our lab studies mechanisms that regulate the maintenance of bone marrow niches for hematopoietic stem cells during homeostasis, aging, or myeloid malignancy.

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U. Thomas Meier, Ph.D.

U. Thomas Meier, Ph.D.

718.430.3294

Areas of Research: Nuclear function and organization: small nucleolar ribonucleoproteins (snoRNPs) and their involvement in inherited disease and cancer. Human reproduction: endometrial receptivity.

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Satish K. Nandakumar, M.B.B.S., Ph.D.

Satish K. Nandakumar, M.B.B.S., Ph.D.

Assistant Professor, Department of Cell Biology

718.430.3021

Areas of Research: Germline predisposition to blood cancers, Hematopoietic stem cells, Clonal hematopoiesis, Myeloproliferative neoplasms, Genetic variants, Enhancer elements, CRISPR/Cas9 edited stem cell models, Multiplexed functional assays.

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Charles C. Query, M.D., Ph.D.

Charles C. Query, M.D., Ph.D.

718.430.4174

Areas of Research: Our laboratory studies the mechanics of a large RNP machine – the spliceosome – focusing on enzyme-substrate interactions. These studies provide insights allowing us to “reverse engineer” new orthogonal spliceosome systems.

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Rebeca San Martin, Ph.D.

Rebeca San Martin, Ph.D.

Assistant Professor, Department of Oncology (Medical Oncology)

Assistant Professor, Department of Cell Biology

718.430.3366

Areas of Research: Prostate cancer microenvironment. Bone metastasis and dormancy. Development of alternative in-vitro systems that model progression and metastasis

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Matthew D. Scharff, M.D.

Matthew D. Scharff, M.D.

Distinguished Professor, Department of Cell Biology

Distinguished Professor, Department of Medicine (Infectious Diseases)

The Harry Eagle Chair in Cancer Research/National Women's Division

Faculty Supervisor, Hybridoma

718.430.3527

Areas of Research: Dr. Scharff studies how antibody diversity is generated and protects from infections. The major focus is on how activation induced deaminase and error prone mismatch repair is targeted to antibody variable region genes in mice and humans and in some huma

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Carl L. Schildkraut, Ph.D.

Carl L. Schildkraut, Ph.D.

718.430.2097

Areas of Research: DNA REPLICATION, ALZHEIMER'S DISEASE, AGING, DNA DAMAGE TO GENES INVOLVED IN NEUROLOGICAL DEVELOPMENT, TELOMERE ROLE IN CHROMOSOME STABILITY

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Robert H. Singer, Ph.D.

Robert H. Singer, Ph.D.

Professor, Department of Cell Biology

Professor, Dominick P. Purpura Department of Neuroscience

Harold and Muriel Block Chair in Anatomy & Structural Biology

Chair Emeritus Department of Anatomy & Structural Biology

Co-Director, Gruss-Lipper Biophotonics Center

Co-Director, Integrated Imaging Program

718.430.8646

Areas of Research: We study single mRNA molecules from cradle to grave in single living cells using high resolution imaging. We develop trafficking microscopy and approaches to image RNA using fluorescent probes to visualize and quantify mRNA.

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Arthur I. Skoultchi, Ph.D.

Arthur I. Skoultchi, Ph.D.

Professor, Department of Cell Biology

Judith and Burton P. Resnick Chair in Cell Biology

718.430.2169

Areas of Research: Key Words: Chromatin, epigenetics, transcription, proliferation, differentiation, leukemia. We study control of gene expression in mouse embryonic stem cells, normal and leukemic blood cells, and in Drosophila.

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Pamela Stanley, Ph.D.

Pamela Stanley, Ph.D.

Professor, Department of Cell Biology

The Horace W. Goldsmith Foundation Chair

718.430.3346

Areas of Research: Roles of mammalian glycans in development, spermatogenesis, immunity and cancer; glycosylation engineering; CHO and mouse glycosylation mutants to identify roles for glycans in growth factor receptor and Notch signaling.

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Kristy R. Stengel, Ph.D.

Kristy R. Stengel, Ph.D.

Assistant Professor, Department of Cell Biology

718.430.2815

Areas of Research: Gene expression, Cancer, Transcription factors, Epigenetics, Chromatin structure, Targeted protein degradation

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Britta Will, Ph.D.

Britta Will, Ph.D.

Associate Professor, Department of Oncology (Medical Oncology)

Associate Professor, Department of Medicine (Oncology & Hematology)

Associate Professor, Department of Cell Biology

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Stem Cell & Cancer Biology Program

Director, Preclinical Modeling Montefiore Einstein Comprehensive Cancer Center Blood Cancer Institute

718.430.3786

Areas of Research: Hematopoietic Stem Cells (HSC), Regulation of Stem Cell Fate, Aging, Myelodysplastic Syndrome and Acute Myeloid Leukemia, Mouse Models of Leukemogenesis, Testing of novel stem cell-directed therapeutics on primary human HSCs.

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B. Hilda Ye, Ph.D.

B. Hilda Ye, Ph.D.

Associate Professor, Department of Cell Biology

718.430.3339

Areas of Research: We are studying how transcription regulation and cell signaling events govern lymphocyte differentiation and lymphoma development. The current focus is on diffuse large B-cell lymphoma and adult T-cell leukemia/lymphoma

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