Rebeca San Martin, Ph.D.
- Assistant Professor, Department of Oncology (Medical Oncology)
- Assistant Professor, Department of Cell Biology
- Co-Chair, Women’s Initiative Network, Montefiore Einstein Comprehensive Cancer Center
Area of research
- Prostate cancer microenvironment. Bone metastasis and dormancy. Development of alternative in-vitro systems that model progression and metastasis
Phone
Location
- Albert Einstein College of Medicine Jack and Pearl Resnick Campus 1300 Morris Park Avenue Ullmann Building 713 Bronx, NY 10461
Research Profiles
Selected Publications
San Martin R, Moffitt A, Loveless T, Brixius-Anderko S (2023). Recruiting women faculty through inclusive, family-friendly practices. Trends Biochem Sci. 2023 Apr;48(4):311-314. doi: 10.1016/j.tibs.2023.01.003. PMID: 36754683.
San Martin, R. Das, P., Sanders, J.T., Hill, A.M., McCord R.P. (2022). Transcriptional profiling of Hutchinson- Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification eLife 11:e81290. https://doi.org/10.7554/eLife.81290
San Martin, R., Das, P., Dos Reis Marques, R., Xu, Y., Roberts, J. M., Sanders, J. T., . . . McCord, R. P. (2022). Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression. J Cell Biol, 221(2). doi:10.1083/jcb.202104108
San Martin, R., Pathak, R., Jain, A., Jung, S. Y., Hilsenbeck, S. G., Pina-Barba, M. C., . . . Rowley, D. R. (2017). Tenascin-C and Integrin alpha9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment. Cancer Res, 77(21), 5977-5988. doi:10.1158/0008-5472.CAN-17-0064
San Martin, R., Barron, D. A., Tuxhorn, J. A., Ressler, S. J., Hayward, S. W., Shen, X., . . . Rowley, D. R. (2014). Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. Am J Pathol, 184(6), 1860-1870. doi:10.1016/j.ajpath.2014.02.021
Tindall, D. (2013). Prostate cancer: biochemistry, molecular biology, and genetics (San Martin R., Rowley, D.R.. Chapter 2. Role of reactive stroma in prostate cancer). New York: Springer.
Co-Author
Das P, San Martin R, McCord RP. (2023) Differential contributions of nuclear lamina association and genome compartmentalization to gene regulation. Nucleus. doi: 10.1080/19491034.2023.2197693. PMID: 37017584; PMCID: PMC10078145.
McCord RP, Xu Y, Li H, Das P, San Martin R. (2022). SnapShot: Chromosome organization. Mol Cell. 16;82(12):2350-2350.e1. doi: 10.1016/j.molcel.2022.05.020. PMID: 35714589.
Humphries, B. A., Hwang, P. Y., Kendrick, A. A., Kulkarni, R. P., Pozzar, R. A., & San Martin, R. (2021). Overstretched and overlooked: solving challenges faced by early-career investigators after the pandemic. Trends Cancer, 7(10), 879-882. doi:10.1016/j.trecan.2021.07.005
Sanders, J. T., Freeman, T. F., Xu, Y., Golloshi, R., Stallard, M. A., San Martin, R., . . . McCord, R. P. (2020). Radiation-induced DNA damage and repair effects on 3D genome organization. Nat Commun, 11(1), 6178. doi:10.1038/s41467-020-20047-w
Roberts, J. M., San Martin, R. Piyarathna, D. B., MacKrell, J. G., Rocha, G. V., Dodge, J. A., . . . Weigel, N. L. (2017). Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG. Oncotarget, 8(27), 44447-44464. doi:10.18632/oncotarget.17968
Montico, F., Kido, L. A., San Martin, R., Rowley, D. R., & Cagnon, V. H. (2015). Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences. Prostate, 75(14), 1643-1661. doi:10.1002/pros.23045
Kim, W., Barron, D. A., San Martin, R., Chan, K. S., Tran, L. L., Yang, F., . . . Rowley, D. R. (2014). RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci USA, 111(46), 16389-16394. doi:10.1073/pnas.1407097111