Rebeca San Martin

Rebeca San Martin, Ph.D.

  • Assistant Professor, Department of Oncology (Medical Oncology)
  • Assistant Professor, Department of Cell Biology
  • Co-Chair, Women’s Initiative Network, Montefiore Einstein Comprehensive Cancer Center

Area of research

  • Prostate cancer microenvironment. Bone metastasis and dormancy. Development of alternative in-vitro systems that model progression and metastasis

Email

Phone

Location

  • Albert Einstein College of Medicine Jack and Pearl Resnick Campus 1300 Morris Park Avenue Ullmann Building 713 Bronx, NY 10461


Selected Publications

San Martin R, Moffitt A, Loveless T, Brixius-Anderko S (2023). Recruiting women faculty through inclusive, family-friendly practices. Trends Biochem Sci. 2023 Apr;48(4):311-314. doi: 10.1016/j.tibs.2023.01.003. PMID: 36754683.

San Martin, R. Das, P., Sanders, J.T., Hill, A.M., McCord R.P. (2022). Transcriptional profiling of Hutchinson- Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification eLife 11:e81290. https://doi.org/10.7554/eLife.81290

 

San Martin, R., Das, P., Dos Reis Marques, R., Xu, Y., Roberts, J. M., Sanders, J. T., . . .      McCord, R. P. (2022). Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression. J Cell Biol, 221(2). doi:10.1083/jcb.202104108

 

San Martin, R., Pathak, R., Jain, A., Jung, S. Y., Hilsenbeck, S. G., Pina-Barba, M. C., . . . Rowley, D. R. (2017). Tenascin-C and Integrin alpha9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment. Cancer Res, 77(21), 5977-5988. doi:10.1158/0008-5472.CAN-17-0064

 

San Martin, R., Barron, D. A., Tuxhorn, J. A., Ressler, S. J., Hayward, S. W., Shen, X., . . . Rowley, D. R. (2014). Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. Am J Pathol, 184(6), 1860-1870. doi:10.1016/j.ajpath.2014.02.021

 

Tindall, D. (2013). Prostate cancer: biochemistry, molecular biology, and genetics (San Martin R., Rowley, D.R.. Chapter 2. Role of reactive stroma in prostate cancer). New York: Springer.

 

Co-Author

Das P, San Martin R, McCord RP. (2023) Differential contributions of nuclear lamina association and genome compartmentalization to gene regulation. Nucleus. doi: 10.1080/19491034.2023.2197693. PMID: 37017584; PMCID: PMC10078145.

McCord RP, Xu Y, Li H, Das P, San Martin R. (2022). SnapShot: Chromosome organization. Mol Cell. 16;82(12):2350-2350.e1. doi: 10.1016/j.molcel.2022.05.020. PMID: 35714589.

 

Humphries, B. A., Hwang, P. Y., Kendrick, A. A., Kulkarni, R. P., Pozzar, R. A., & San Martin, R. (2021). Overstretched and overlooked: solving challenges faced by early-career investigators after the pandemic. Trends Cancer, 7(10), 879-882. doi:10.1016/j.trecan.2021.07.005

 

Sanders, J. T., Freeman, T. F., Xu, Y., Golloshi, R., Stallard, M. A., San Martin, R., . . . McCord, R. P. (2020). Radiation-induced DNA damage and repair effects on 3D genome organization. Nat Commun, 11(1), 6178. doi:10.1038/s41467-020-20047-w

 

 

Roberts, J. M., San Martin, R. Piyarathna, D. B., MacKrell, J. G., Rocha, G. V., Dodge, J. A., . . . Weigel, N. L. (2017). Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG. Oncotarget, 8(27), 44447-44464. doi:10.18632/oncotarget.17968

 

Montico, F., Kido, L. A., San Martin, R., Rowley, D. R., & Cagnon, V. H. (2015). Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences. Prostate, 75(14), 1643-1661. doi:10.1002/pros.23045

 

Kim, W., Barron, D. A., San Martin, R., Chan, K. S., Tran, L. L., Yang, F., . . . Rowley, D. R. (2014). RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation. Proc Natl Acad Sci USA, 111(46), 16389-16394. doi:10.1073/pnas.1407097111