Center for Epigenomics
La misión del Centro de Epigenómica del Colegio de Medicina Albert Einstein es estudiar la genómica funcional y celular.
We are pursuing two cellular models for human disease. One is the conventional idea that cells change characteristics in response to DNA sequence variation or environmentally-mediated transcriptional regulatory changes. The other is by altering the repertoire of cell subtypes in a tissue, what we have referred to as "polycreodism."
The center provides two major resources to study functional and cellular genomics, an Epigenomics Shared Facility and a Computational Genomics Core Facility. The combination of these resources allows genome-wide experiments to be performed with automated data analysis, facilitating the ability of the investigator to study their biological question of interest.
Nuestro objetivo es facilitar la realización de estudios sobre las propiedades del genoma, abriendo este campo de investigación a los no especialistas. El Centro apoya un amplio espectro de intereses de investigación, pero tiene como objetivo principal apoyar los estudios sobre el papel de los mecanismos de las enfermedades humanas.
Ensayos epigenómicos
Instalación Compartida Epigenómica (ESF)
The Epigenomics Shared Facility (ESF) has facilities for massively-parallel sequencing-based assays, using Illumina platforms, and with outsourcing of some sequencing services to the New York Genome Center.
To see the services offered, please visit our assay portal.
Los protocolos están disponibles a pedido.
Análisis de datos epigenómicos
Centro de recursos e instalaciones de genómica computacional
Si bien el sistema WASP resuelve el problema del análisis de datos primarios para muchas aplicaciones, los análisis integrativos y otras cuestiones que no se pueden automatizar requieren otras soluciones.
Contamos con un Centro de Genómica Computacional para este propósito, que trabajará con usted para resolver su problema a cambio de un cargo por servicio.
We can also direct you to the faculty of our Division of Computational Genetics, and to other Einstein resources such as the Department of Systems and Computational Biology and our Biostatistics Core Facility.
Planificación de proyectos y subvenciones
Servicios de consulta epigenética traslacional
Please contact Masako Suzuki for more information.
Carta de apoyo
The Center for Epigenomics has text descriptions available for assays, analysis, and the Resources section of grant proposals. We are also happy to provide a letter of support for your proposal. Please contact Juan Greally for more details.