GI & Liver Diseases Faculty Well Represented at AASLD 2014 Meeting

BRONX, NY - November 26, 2014 - The Montefiore Einstein Division of Gastroenterology & Liver Diseases faculty were well represented at the 65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), held November 7-11, 2014 at the Hynes Convention Center in Boston, MA.

Drs. Mark J. Czaja, Sanjeev Gupta, Jayanta Roy-Chowdhury, Allan Wolkoff and Paul Gaglio were honored as members of the first inaugural AASLD Fellows class of 2014.

Dr. Muhammad Amir (Mentor: Dr. Mark Czaja) received of the 2014 AASLD Emerging Liver Scholar Award.

Dr. Preeti Viswanathan (Mentor: Dr. Sanjeev Gupta) received the 2014 AASLD Pediatric Research Award.

Courses

1. Catalysts for Innovation in Liver Transplantation
   Course Director(s): P.J. Gaglio, M. Navasa, J. Renz
2. Clinical Implications of Inflammation and Immunity in Acute and Chronic Liver Diseases - Advances in Diagnosis, Treatment and Clinical Practice 
   Moderator: M.J. Czaja, N. Terrault

Posters & Presentations

1. P.J. Gaglio, W. Rabbenou, S.S. Florman, T. Kato, M. Kinkhabwala, G. Morgan, M.S. Orlof, L. Teperman, S. DeLair
   Utilization of Simultaneous Liver-Kidney Transplants Continues to Vary Dramatically by UNOS Region
2. C.S. Law, M. Chatterji, K. Chacko, T.D. Schiano, C.Y. Chang
   Incidence and Outcome of Newly Diagnosed Portal Vein Thrombosis in Patients with Cirrhosis Awaiting Liver Transplantation
3. P. Viswanathan, Y. Sharma, S. Bandi, S. Gupta
   Paracrine Signaling from Transplanted Hepatocytes but Not from Liver Sinusoidal Endothelial Cells (LSEC) Rescues Mice from Acetaminophen (APAP)-Induced Acute Liver Failure (ALF)
4. J.M. Schwartz, C. Shelton, A. Aljanab, M.A. Alani, D. Ginzberg, A.J. Marcus, J. Chapochnick-Friedmann, S. Bellemare, Y. Golowa, J. Cynamon, A. Kaubisch, N. Ohri, M. Kinkhabwala
   Surgical and Percutaneous Ablation are Both Safe and Effective in Patients with Small Hepatocellular Carcinoma
5. P. Viswanathan, S. Kapoor, B. Joseph, E. Berishvilli, S. Gupta
   Thalidomide Pretreatment Improves Cell Engraftment and Liver Repopulation Independently of Chemokines/Cytokines/Receptors Expressed After Neutrophil or Kupffer Cell Activation
6. P.J. Gaglio, C.E. Glick, J.F. Reinus
   Survey on Pre- and Post-Transplant Management of Hepatitis C: Response from Medical Directors of US Transplant Programs
7. N. Pattamanuch, P. Viswanathan, S. Bandi, L.E. Rogler, C.E. Rogler, S. Gupta
   Acetaminophen (APAP)-Induced Acute Liver Failure (ALF) Leads to Activation of Endogenous Hepatic Stem/Progenitor Cells with Inability to Complete Hepatic Regeneration
8. P. Viswanathan, S. Bandi, S. Gupta
   Acetaminophen (APAP) Hepatotoxicity Leads to DNA Damage-Induced Arrest of Injured Cells in G0/G1 Through Involvement of Cell Cycle Regulators
9. E. Zhao, G. Ilyas, Y. Lin, K. Tanaka, F. Ravenelle, M.J. Czaja
   A Novel Oral Form of Pentamidine (Ocz103) Blocks TNF-Mediated Mouse Liver Injury from GalN/LPS
10. J.W Murray, A.W. Wolkoff
    3-Dimensional Culturing of Hepatocytes Increases Fluorescent Bile Acid Accumulation and Sensitivity to Drug Induced Cell Death
11. N. Pattamanuch, P. Viswanathan, S.O. Suadicani, D.C. Spray, S. Gupta
    NMDA Receptor Activity Contributes in Cellular DNA Damage Following Acetaminophen Hepatotoxicity and Offers Directions for Therapeutic Development
12. N. Yadav, A. Follenzi, R. Badhe, S. Gupta
    Liver Repopulation with Transplanted Liver Sinusoidal Endothelial Cells (LSEC) Benefits from Prior Disruption of Native Endothelial Cells as Well as Endothelin-1 Receptor Blockade in Donor Cells
13. The Cell Biology of Hepatic Disease
    Moderator(s): M. McNiven, N. Torok, A.W. Wolkoff, N. Nieto, Y. Iwakiri, M. Anwer
14. W. Zhang, P. Asp, B. Vaitheesvaran, L. Liu, R. Kabarriti, H. Yaffe, R. Sellers, N. Roy-Chowdhury, J. Roy-Chowdhury, M. Grompe, T. Scanlan, C. Guha
    A Thyroid Hormone Receptor Beta-Selective T3 Analog Promotes Liver Repopulation in Apolipoprotein E-Deficient Mice, Correcting Hypercholesterolemia
15. K. Li, E. Zhao, G. Ilyas, G. Lalazar, Y. Lin, K. Tanaka, M.J. Czaja
    Impaired Macrophage Autophagy Triggers Steatohepatitis in Obese Mice by Promoting Proinflammatory Macrophage Polarization
16. M.J. Czaja & J.J. Lemasters
    Autophagy in Ash and Nash
17. R.J. Fontana, K. Herzer, P. Ferenci, A. Moreno, R. Bahirwani, R. Brown, K. Chacko, C. Durand, R. Lionetti, M. Loiacono, S. Joshi, V. Knop, M. Londono, M. Montalbano, A.M. Pellicelli, A. Mubarak, R. Reddy, C.P. Berg
    High Efficacy and Favorable Safety Profile of Daclatasvir Based All Oral Antiviral Therapy in Liver Transplant Recipients With Severe Recurrent HCV
18. X. Wang, E. Bejerano-Fernandez, J.W. Murray, A.M. Cuervo, A.W. Wolkoff
    Characterization of Microtubule-Based Motility of Autophagic Vesicles from Mouse Liver
19. Y. Sharma, T. Tchaikovskaya, P. Viswanathan, D.B. Rhee, P.O. Broin, T. Gorbacheva, A.Y. Maslov, A. Golden, S. Gupta
    Characterization of Exosomal Microrna (MIRNA) Content Following Hepatic Injury and Roles in Cytoprotection After Uptake of Exosomes by Injured Hepatocytes
20. Y. Lee, L.A. Noon, T. Lee, K.M. Akat, M-L Berres, H. Chou, C Pfleger, E.G. Kramer, G. John, M.I. Fiel, R.E. Gordon, Y. Hoshida, M.J. Czaja, S.L. Friedman
    Hepatic Growth Regulation and Tumorigenesis is Linked to Autophagy Via the Hippo Tumor Suppressor Pathway
21. M. Yovchev, F.L. Jaber, S. Patel, J. Locker, L.E. Rogler, J.W. Murray, M.D. Dabeva, L. Zhu, D. Shafritz
    Controlled Repopulation of Normal Rat Liver by WT Hepatocytes Expressing a Tamoxifen Regulated Liver Growth Gene, YapERT2
22. The Good and Bad of Innate Immunity in Liver Disease
    Moderator(s): P. Mandrekar & M.J. Czaja 
23. S. Gupta & L. Mishra
    Stem Cells and Regeneration in Liver Disease
24. V. Sauer, X. Wang, K. Tar, T. Tchaikovskaya, Y. Li, C. Guha, J. Roy Chowdhury, N. Roy-Chowdhury
    Generation of Human Hepatocyte-Like Cells from Urine