Dr. Minniti is Professor of Clinical Medicine and Pediatrics at Einstein College of Medicine. Additionally, she is Director of the Sickle Cell Center for Adults at Montefiore Medical Center, whose mission is to provide exceptional, seamless, comprehensive, compassionate and individualized care, education, counseling, and research for people living with sickle cell disease (SCD). Dr. Minniti is a clinical trial specialist and a translational researcher who believes that the best way to provide care for SCD patients is on a continuum, from birth to adulthood.

Dr. Minniti's research focuses on understanding mechanisms that lead to end organ damage in order to identify early biomarkers and targeted therapies. Her interests have spanned from stroke to pulmonary hypertension and, most recently, leg ulcers as they represent a window into the vasculopathy in SCD. She aims to develop pathogenetically based therapeutic approaches for preventing and treating SCD-related end organ damage. Before relocating to New York, she was a member of the Hematology Branch of the National Institute of Heart Blood and Lung, where she developed a topical treatment for chronic leg ulcers in SCD.