(Most recent publications)
Kim WK, Buckley AJ, Lee DH, Hiroto A, Nenninger CH, Olson AW, Wang J, Adzavon YM, Bao Y, Kahn M, Xiao GQ, Geradts J, Sun ZJ (2024). Androgen Deprivation Induces Double-Null Prostate Cancer via Aberrant Activating Nuclear Exporting and Ribosomal Biogenesis by HGF and Wnt Axes. Nat Communs 15(1):1231. PMID: 383363745
Kim J, Freeman K, Ayala A, Mullen M, Sun ZJ, Rhee JW (2023). Cardiovascular impact of androgen deprivation therapy: from basic biology to clinical practice. Current Oncol Rep. doi: 10.1007/s11912-023-01424-2. PMID: 37273124
Alghamdi TA, Krentz NAJ, Smith N, Spigelman AF, Rajesh V, Jha A, Ferdaoussi M, Suzuki K, Yang J, Manning Fox JE, Sun H, Sun ZJ, Gloyn AL, MacDonald PE (2022). Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding. Mol Metab. 2022 Dec;66:101621. doi: 10.1016/j.molmet.2022.101621. Epub 2022 Oct 26.PMID: 36307047
Hiroto A, Kim WK, Pineda A, He Y, Lee DH, Le V, Olson AW, Aldahl J, Nenninger CH, Buckley AJ, Xiao GQ, Geradts J, Sun ZJ (2022). Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis. Nat Communs. 13(1):6552. PMID: 36323713
Kim WK, Olson AW, Le V, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff RD, You SY, Sun ZJ. (2022). Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes. Nat Communs, 28;13 (1) :4364. PMID:35902588, PMCID: PMC9334353
Olson AW, Le V, Wang J, Hiroto A, Kim WK, Lee DH, Aldahl J, Wu X, Kim M, Cunha GR, You S, Sun ZJ (2021). Stromal androgen and hedgehog signaling regulates stem cell niches in pubertal prostate development. Development. PMID: 34427305
Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun ZJ (2021). Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. doi: 10.1242/dev.196048. PMID: 33318148
He Y, Mi J, Olson A, Aldahl J, Hooker E, Yu EJ, Le V, Lee DH, Kim WK, Robins DM, Geradts J, Sun ZJ (2020). Androgen receptor with short polyglutamine tract preferably enhances Wnt/ß-catenin-mediated prostatic tumorigenesis. Oncogene. 39(16):3276-3291.PMID: 32089544
Le V, He Y, Aldahl J, Hooker E, Yu EJ, Olson A, Kim WK, Lee DH, Wong M, Sheng R, Mi J, Geradts J, Cunha GR, Sun ZJ (2020). Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration. PLoS Genet. 16(1):e1008588. PMID: 31929563, PMCID: PMC6980684
Aldahl J, Mi J, Pineda A, Kim WK, Olson A, Hooker E, He Y, Yu EJ, Le V, Lee DH, Geradts J, Sun ZJ (2020). Aberrant activation of hepatocyte growth factor/MET signaling promotes ß-catenin-mediated prostatic tumorigenesis. J Biol Chem. 295(2):631-644. doi: 10.1074/jbc.RA119.011137. PMID: 31819003
He YF, Hooker E, Yu EJ, Wu H, Xu JM, Cunha GR, Sun ZJ (2019). Androgen signaling is essential for development of prostate cancer initiated from prostatic basal cells. Oncogene. 38(13):2337-2350. doi: 10.1038/s41388-018-0583-7. PMID: 30510232
He YF, Johnson DT, Yang JS, Wu H, You S, Yoon J, Lee DH, Kim WK, Aldahl J, Le V, Hooker E, Yu EJ, Geradts J, Cardiff RD, Sun ZJ (2019). Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. Oncogene. 38(38):6507-20. doi: 10.1038/s41388-019-0901-8. Epub 2019 Jul 29. PMID: 31358900
Olson A, Le V, Aldahl J, Yu EJ, Hooker E, He Y, Lee DH, Kim WK, Cardiff RD, Geradts J, Sun ZJ (2019). The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression. PLoS Genet. 15(10):e1008451. doi: 10.1371/journal.pgen.1008451. PMID: 31658259,
Aldahl J, Yu EJ, He YF, Hooker E, Wong M, Le V, Olson A, Lee DH, Kim WK, Murtaugh CL, Cunha GR, Sun ZJ (2019). A pivotal role of androgen signaling in notch-responsive cells in prostate development, maturation, and regeneration. Differentiation, 2019 May-Jun;107:1-10. PMID: 309276418.
He YF, Hooker E, Yu EJ, Wu H, Cunha GR, Sun ZJ (2018). An indispensable role of androgen receptor in Wnt responsive cells during prostate development, maturation, and regeneration. Stem Cells. Jun; 36(6):891-902. doi: 10.1002/stem.2806. PMID: 29451339
Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He YF, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo M, Sun ZJ (2018). Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor progression in the murine prostate. J Biol Chem. 293(52):20123-20136. PMID: 30401749