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Bible, K.C., Kebebew, E., Brierley, J., Brito, J.P., Cabanillas, M.E., Clark, T.J., Di Cristofano, A., Foote, R., Giordano, T., Kasperbauer, J., Newbold, K., Nikiforov, Y.E., Randolph, G., Rosenthal, M.S., Sawka, A.M., Shah, M., Smallridge, R., Wong-Clark, C.K. 2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer. Thyroid, 31: 337-386, 2021.
- Shanja-Grabarz, X., Coste-Abramson, A., Entenberg, D., and Di Cristofano, A. Real-time, high-resolution imaging of tumor cells in thyroid cancer mouse models. Endocr. Relat. Cancer, 27: 529-539, 2020.
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Jezek, J. , Wang, K., Yan, R., Di Cristofano, A., Cooper, K., and Strich, R. Synergistic repression of thyroid hyperplasia by cyclin C and Pten. J. Cell Sci.132, jcs230029. doi:10.1242/jcs.230029, 2019.
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Wong, K., Di Cristofano, F., Ranieri, M., De Martino, D., and Di Cristofano, A. PI3K/mTOR inhibition potentiates and extends palbociclib activity in anaplastic thyroid cancer. Endocr. Relat. Cancer, 26: 425-436, 2019.
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De Martino, D., Yilmaz, E., Orlacchio, A., Ranieri, M., Zhao, K., and Di Cristofano, A. PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer. Cancer Lett.439: 56-65, 2018.
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Orlacchio, A., Ranieri, M., Brave, M., Antico Arciuch V., Forde, T., De Martino, D., Anderson, K.E., Hawkins, P., and Di Cristofano, A. SGK1 is a critical component of an AKT-independent pathway essential for PI3K-mediated tumor development and maintenance. Cancer Res., 77: 6914-6926, 2017.
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Champa, D., Orlacchio, A., Patel, B. Ranieri, M., Shemetov, A.A., Verkhusha, V.V., Cuervo, A.M., and Di Cristofano, A. Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis. Oncotarget, 7: 34453-34471, 2016.
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Champa, D., Russo, M.A., Liao, X-H., Refetoff, S., Ghossein, R.A., and Di Cristofano, A. Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression. Endocr. Relat. Cancer, 21:755-767, 2014.
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Antico Arciuch V.G., Russo, M.A., Kang, K.S, and Di Cristofano, A. Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells. Cancer Res., 73: 5459-5472, 2013.
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Russo, M.A., Kang, K.S., and Di Cristofano, A. The PLK1 inhibitor GSK461364A is effective in poorly differentiated and anaplastic thyroid carcinoma cells, independent of the nature of their driver mutations. Thyroid, 23:1284-1293, 2013.
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Antico Arciuch V.G., Russo, M.A., Dima, M., Kang, K.S., Dasrath, F., Liao, X-H., Refetoff, S., Montagna, C., and Di Cristofano, A. Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget, 2:1109-1126, 2011.
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Dima, M., Miller, K.A., Antico-Arciuch V.G., and Di Cristofano, A. Establishment and characterization of cell lines from a novel mouse model of poorly differentiated thyroid carcinoma: powerful tools for basic and preclinical research. Thyroid, 21:1001-1007, 2011.
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Antico-Arciuch VG, Dima, M., Liao, X-H., Refetoff, S., and Di Cristofano, A. Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females. Oncogene, 29:5678-5686, 2010.
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Miller, K., Yeager, N., Baker, K., Liao, X-H., Refetoff, S., and Di Cristofano, A. Oncogenic Kras Requires Simultaneous PI3K Signaling to Induce ERK Activation and Transform Thyroid Epithelial Cells in Vivo. Cancer Res., 69:3689-3694, 2009.