Investigators in the Department of Cell Biology at Albert Einstein College of Medicine who study immunology and virology explore the development and malignant transformation of B and T cells, as well as roles played by innate and adoptive immunity in lung and breast cancers. We identify markers and drivers of different stages in these processes to test diagnostic and therapeutic opportunities including CAR-T and immune checkpoint immunotherapy. Our labs specifically investigate the molecular regulation of antibodies; the entry, intracellular lifecycle, and budding of flaviviruses and alphaviruses including human pathogens; and the processes by which HTLV-1 causes adult T-cell leukemia/lymphoma.
Research Faculty
The Department of Cell Biology faculty below conduct research on immunology and virology. If you are interested in collaborating on a research project, please contact the investigators directly for more information.
Maria Cecilia Campos Canessa, Ph.D.
Assistant Professor, Department of Cell Biology
Specific research topics: cancer microenvironment, development, immunology, single cell analysis
Nicholas Chiorazzi, M.D.
Adjunct Professor, Department of Cell Biology
Specific research topics: cancer microenvironment, immunology, and single cell analysis
John S. Condeelis, Ph.D.
Professor, Departments of Cell Biology and Surgery; The Judith and Burton P. Resnick Chair in Translational Research
Specific research topics: cancer dormancy and metastasis, cancer microenvironment, cell-based- and gene-therapy, drug development and experimental therapeutics, imaging, membrane trafficking, signal transduction, and stem cells
Kira Gritsman, M.D., Ph.D.
Associate Professor, Departments of Cell Biology, Medicine, and Oncology; Co-Leader, Montefiore Einstein Comprehensive Cancer Center
Specific research topics: cancer dormancy and metastasis, cancer microenvironment, chromatin biology/gene regulation, drug development and experimental therapeutics, erythropoiesis, hematopoiesis, immunology, proteomics and protein biochemistry, RNA processing/splicing/modification, signal transduction, and stem cells
Wenjun Guo, Ph.D.
Professor, Department of Cell Biology
Specific research topics: cancer dormancy and metastasis, cancer genetics, cancer microenvironment, cellular metabolism, chromatin biology/gene regulation, development, immunology, signal transduction, single cell analysis, and stem cells
Margaret Kielian, Ph.D.
Professor Emerita, Department of Cell Biology
Specific research topics: drug development and experimental therapeutics, membrane trafficking, proteomics and protein biochemistry, and virology
Matthew D. Scharff, M.D.
Distinguished University Professor Emeritus, Departments of Cell Biology and Medicine; Faculty Supervisor, Hybridoma Facility
Specific research topics: chromatin biology/gene regulation, development, DNA replication and repair, immunology, and proteomics and protein biochemistry
Pamela Stanley, Ph.D.
Professor Emerita, Department of Cell Biology
Specific research topics: cancer genetics, development, drug development and experimental therapeutics, glycobiology/glycomics, hematopoiesis, immunology, membrane trafficking, proteomics and protein biochemistry, signal transduction, and stem cells
B. Hilda Ye, Ph.D.
Professor, Department of Cell Biology
Specific research topics: cancer genetics, cancer microenvironment, drug development and experimental therapeutics, immunology, signal transduction, single cell analysis, and stem cells.