Montefiore Einstein Department of Medicine

Department Faculty

Dr. William N. Southern, M.D.,  M.S.

William N. Southern, M.D., M.S.

Professor, Department of Medicine (Hospital Medicine)

Chief, Division of Hospital Medicine at the Albert Einstein College of Medicine and Montefiore Medical Center, Department of Medicine

Professional Interests

A 1992 graduate of Albert Einstein College of Medicine, Dr. Southern completed residency training in Internal Medicine at the Mount Sinai Medical Center program (1992-1995).  In July 1995, Dr. Southern joined the faculty at the Mount Sinai School of Medicine as a clinician educator and Hospitalist where he was actively involved with teaching medical students and residents.  In July 2002, Dr. Southern joined the faculty at Einstein as an Assistant Professor of Medicine and Teaching Hospitalist.

Since that time Dr. Southern has played many active teaching roles with Montefiore Internal Medicine Residents, Jacobi Internal Medicine Residents, and Einstein medical students. Dr. Southern has served as the Director of Hospitalist Services and the Associate Medical Director at Weiler. In June 2007, he received a MS in Clinical Research Methods and has published in the area of hospital medicine outcomes research.  In January of 2009, he was appointed the Chief of the Section of Hospital Medicine at Montefiore Einstein.

Dr. Southern is presently Associate Professor of Clinical Medicine at Einstein, and a Senior Fellow of Hospital Medicine in the Society of Hospital Medicine. 

Current Investigations

  • Effect of Physician Years of Experience on Length-of-Stay, Readmission, and Mortality on an Inpatient Medical Teaching Service.
  • Increased Short-Term Mortality Associated with Mildly Elevated Non-Rising Troponin T in Patients with Underlying Renal Disease Suspected of Acute Myocardial Ischemia.
  • Informed Consent and Patient Coping Style:  Does Synchrony Lead to Less Anxiety and Dyssynchrony to More Anxiety Before Endoscopic Procedures?
  • Post-Surgical Clostridium difficile Infection


  • Montefiore Health Services Research Career Development Award for "The Effect of Hospitalists and Physician Years-in-Practice on the Quality of Inpatient Care"

Material in this section is provided by individual faculty members who are solely responsible for its accuracy and content.

Montefiore Medical Center
111 East 210th Street
North Pavilion, Room 848
Bronx, NY 10467

Tel: 866.633.8255
Fax: 718.654.6908

Research Information

In the News

A Blood Test May Show Which COVID-19 Patients Steroids Will Help�Or Harm

Marla Keller, M.D., Will Southern, M.D., M.S., and Shitij Arora, M.D., are co-authors on a study that finds a blood test can help physicians determine which hospitalized patients with COVID-19 can benefit from steroids. Dr. Keller is vice chair of research in the department of medicine; Dr. Southern is chief of hospital medicine; and Dr. Arora is associate professor of medicine and a hospitalist at Montefiore.

Additional coverage includes USA Today, LoHud, Fox News, US News & World Report (via HealthDay), Daily Mail, LabPulse

Steroid Treatment for COVID-19 Has NYC Doctors Cautiously Optimistic

Will Southern, M.D., M.S., and Shitij Arora, M.B.B.S., comment on an unpublished U.K. study that found the steroid dexamethasone helped patients with severe COVID-19, a finding consistent with their upcoming paper on steroid use in Montefiore's hospitalized patients. Dr. Southern is professor of medicine and chief of the division of hospital medicine at Einstein and Montefiore. Dr. Arora is associate professor of medicine at Einstein and an internist at Montefiore.

Additional coverage includes WIRED

More media coverage