Department Chair Jonathan M. Backer, M.D. Professor, Department of Molecular Pharmacology Professor, Department of Biochemistry Chair Department of Molecular Pharmacology William S. Lasdon Chair in Pharmacology Department of Molecular Pharmacology Associate Director, Shared Resources Montefiore Einstein Comprehensive Cancer Center 718.430.2153jonathan.backer@einsteinmed.edu Areas of Research: Signal transduction; Phosphoinositide kinases; Tumor metastasis; Vesicular trafficking; macropinocytosis View Profile Lab Heads Michael Aschner, Ph.D. Professor, Department of Molecular Pharmacology Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Pediatrics Harold & Muriel Block Chair in Molecular Pharmacology Director, Einstein Center of Toxicology 718.430.2317michael.aschner@einsteinmed.edu Areas of Research: Mechanisms of mercury- and manganese-induced neurotoxicity, genetic factors associated with mercury and manganese toxicity, the role of dopamine signaling in susceptibility of dopaminergic neurodegeneration, metals in restless legs syndrome, neurotoxicolo View Profile Michael D. Brenowitz, Ph.D. Professor, Department of Biochemistry Professor, Department of Molecular Pharmacology 718.430.3179michael.brenowitz@einsteinmed.edu Areas of Research: Exploring how protein, DNA, and RNA structure, folding, and assembly determines the biological function of these macromolecules. View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Edward Chu, M.D., M.M.S. Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Molecular Pharmacology Interim Chair Department of Oncology Director, Montefiore Einstein Comprehensive Cancer Center Carol and Roger Einiger Professor of Cancer Medicine 718.430.2303edward.chu@einsteinmed.edu View Profile Kelvin Davies, Ph.D. Professor, Department of Urology Professor, Department of Molecular Pharmacology 718.430.3201kelvin.davies@einsteinmed.edu Areas of Research: i) Erectile dysfunction, ii) Nerve regeneration, iii) Overactive bladder, iv) Male factor infertility, v) Prostate cancer, vi) Nanoparticle delivery systems, vii) Opiorphin, viii) Nitric Oxide, ix) Sickle cell disease, x) Priapism. View Profile Eugen Dhimolea, Ph.D. Assistant Professor, Department of Molecular Pharmacology 718.430.4121eugen.dhimolea@einsteinmed.edu Areas of Research: Cancer biology, treatment-persistent cancer cell states, tumor microenvironment, tumor cell dormancy, adaptive drug-resistance mechanisms in cancer cells, 3D cultures/organoids, immunotherapies in cancer View Profile Lloyd D. Fricker, Ph.D. Professor, Department of Molecular Pharmacology Professor, Dominick P. Purpura Department of Neuroscience 718.430.4225lloyd.fricker@einsteinmed.edu Areas of Research: Neuropeptides and other peptides that function in intercellular and intracellular signaling; peptidases that generate biologically active peptides. View Profile Matthew J. Gamble, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Cell Biology 718.430.2942matthew.gamble@einsteinmed.edu Areas of Research: Histone variant macroH2A; Cancer; Cellular senescence; Chromatin structure and function; Transcription; Splicing; Senescence-associated secretory phenotype; Endoplasmic reticulum stress responses; Poly(ADP-ribose) polymerase View Profile Louis Hodgson, Ph.D. Professor, Department of Molecular Pharmacology 718.678.1027louis.hodgson@einsteinmed.edu Areas of Research: RhoGTPase in cell motility, Forster Resonance Energy Transfer (FRET) biosensors, live-cell imaging, Cancer invasion and metastasis, Invadosome, Actin cytoskeleton, Leading edge cell dynamics during protrusion View Profile Derek M. Huffman, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Medicine (Endocrinology) Lotti and Bernard Benson Faculty Scholar in Alzheimer's Disease 718.430.4278derek.huffman@einsteinmed.edu View Profile Young-Hwan Jo, Ph.D. Professor, Department of Medicine (Endocrinology) Professor, Department of Molecular Pharmacology 718.430.3495young-hwan.jo@einsteinmed.edu Areas of Research: Neurobiology of obesity, Electrophysiological analysis of hypothalamic neurons, Neuronal mapping of feeding-related circuits, Behavioral evaluation of cell type-specific circuit connections using optogenetics View Profile Marina Konopleva, M.D., Ph.D. Professor, Department of Oncology (Medical Oncology) Professor, Department of Molecular Pharmacology Miriam Mandel Faculty Scholar in Cancer Research 718.430.2362marina.konopleva@einsteinmed.edu Areas of Research: Apoptosis Mitochondrial metabolism Leukemia stem cells Immuno-oncology Kinase inhibitors View Profile Chaoyuan Kuang, M.D., Ph.D. Assistant Professor, Department of Oncology (Medical Oncology) Assistant Professor, Department of Medicine (Oncology & Hematology) Assistant Professor, Department of Molecular Pharmacology chaoyuan.kuang@einsteinmed.edu Areas of Research: Preclinical and translational research of colorectal and other GI cancers, apoptosis and regulated cell death, targeted and epigenetic therapies, mechanisms of action and resistance View Profile Sridhar Mani, M.D. Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Molecular Pharmacology Professor, Department of Genetics 718.430.2871sridhar.mani@einsteinmed.edu Areas of Research: Role of Microbiome-Host Interactions in Physiology and Disease, Orphan Nuclear Receptors in Physiology and Disease, Gastrointestinal Cancer, Drug Discovery and Development View Profile Hayley M. McDaid, Ph.D. Associate Professor, Department of Oncology (Medical Oncology) Associate Professor, Department of Medicine (Oncology & Hematology) Associate Professor, Department of Molecular Pharmacology 718.430.8829hayley.mcdaid@einsteinmed.edu Areas of Research: Breast, Lung and Ovarian Cancer, Experimental Therapeutics, Intrinsic and Acquired Drug Resistance, Tubulin ligands, Cancer and Senescence, Senolytics, Biomarker Development View Profile Pabitra K. Parua, Ph.D. Assistant Professor, Department of Molecular Pharmacology 718.430.4284pabitra.parua@einsteinmed.edu Areas of Research: Control of the RNA polymerase II-dependent transcription cycle; Cyclin-dependent kinases (CDKs)-phosphatase antagonisms in regulating chromatin structure, antisense transcription, alternative polyadenylation, transcription elongation, and termination. View Profile Jeffrey E. Pessin, Ph.D. Professor, Department of Medicine (Endocrinology) Professor, Department of Molecular Pharmacology Judy R. and Alfred A. Rosenberg Professorial Chair in Diabetes Research Director, Department of Medicine Diabetes Research Center 718.678.1029jeffrey.pessin@einsteinmed.edu Areas of Research: Regulation of glucose metabolism Epigenetic modifications regulating metabolism Regulation of lipogenic gene transcription and de novo lipogenesis Cardiometabolic health adipocyte and liver biology Integrative metabolic signaling View Profile Gaetano Santulli, M.D., Ph.D. Associate Professor, Department of Medicine (Cardiology) Associate Professor, Department of Molecular Pharmacology 718.430.3370gaetano.santulli@einsteinmed.edu Areas of Research: Aging, Cardiology, Endocrinology, Diabetes Mellitus, Gerontology, Heart Failure, Hypertension, Calcium, microRNA, Endothelium, Mitochondria, Exosomes, Angiogenesis, Physiology, Myocardial Infarction, Pancreatic Beta Cells, Fibrosis. Hirsch Index: 67 View Profile Edward L. Schwartz, Ph.D. Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Molecular Pharmacology 718.430.8864edward.schwartz@einsteinmed.edu Areas of Research: Identification of new targets and novel agents to treat lung and prostate cancer. View Profile David J. Sharp, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Ophthalmology & Visual Sciences Professor, Dominick P. Purpura Department of Neuroscience 718.430.3463david.sharp@einsteinmed.edu Areas of Research: We study the roles of microtubules in cell division, motility and morphogenesis. We are developing therapeutics that target microtubule regulators to enhance wound healing, neural regeneration and cardiovascular disease. View Profile Kosaku Shinoda, Ph.D. Assistant Professor, Department of Medicine (Endocrinology) Assistant Professor, Department of Molecular Pharmacology 718.678.1189kosaku.shinoda@einsteinmed.edu Areas of Research: My lab is focused on the biology of adipocytes. Understanding basic biology of adipocytes is fundamental to the treatment and prevention of type 2 diabetes/obesity. View Profile Kamini Singh, Ph.D. Assistant Professor, Department of Molecular Pharmacology 718.430.2466kamini.singh@einsteinmed.edu Areas of Research: My laboratory investigates the gene expression and therapeutic vulnerabilities in cancer through the lens of the ribosome. We study the mechanisms of mRNA translation and the role of regulatory RNA in cancer progression, metastasis, and immune regulation. View Profile Allen M. Spiegel, M.D. Professor, Department of Medicine (Administration) Professor, Department of Molecular Pharmacology Dean Emeritus 929.246.6738allen.spiegel@einsteinmed.edu View Profile Sylvia O. Suadicani, Ph.D. Professor, Department of Urology Professor, Department of Molecular Pharmacology Assistant Professor, Dominick P. Purpura Department of Neuroscience 718.430.3225sylvia.suadicani@einsteinmed.edu Areas of Research: Urogenital Dysfunction in Diabetes, Multiple Sclerosis, Spinal Cord Injury, Estrogen Deficiency, Aging, Overactive & Underactive Bladder, Female Sexual Dysfunction; Chronic Pelvic Pain; Interstitial Cystitis; Bladder Cancer View Profile Mia M. Thi, Ph.D. Associate Professor, Department of Orthopaedic Surgery Associate Professor, Department of Molecular Pharmacology 718.430.3460mia.thi@einsteinmed.edu Areas of Research: Mechanobiology, Diabetes, Osteoporosis, Osteoarthritis, Estrogen Deficiency, Aging View Profile Emeritus Susan Band Horwitz, Ph.D. Distinguished Professor Emerita, Department of Molecular Pharmacology Rose C. Falkenstein Chair in Cancer Research, Emerita 718.430.2163susan.horwitz@einsteinmed.edu Areas of Research: Research focuses on small molecules of natural product origin, such as Taxol®, which interact with the microtubule cytoskeleton. The goal is to understand, at a molecular level, the effects of drugs on tumor growth. View Profile Curtis F. Brewer, Ph.D. Professor Emeritus, Department of Molecular Pharmacology Professor Emeritus, Department of Microbiology & Immunology 718.430.2227fred.brewer@einsteinmed.edu Areas of Research: Biochemical and biophysical studies of lectin-glycan and glycan-glycan interactions View Profile I. David Goldman, M.D. Professor Emeritus, Department of Oncology (Medical Oncology) Professor Emeritus, Department of Medicine (Oncology & Hematology) Professor Emeritus, Department of Molecular Pharmacology Susan Resnick Fisher Chair in Brain Cancer Research 718.430.2302i.david.goldman@einsteinmed.edu Areas of Research: Membrane transport of folates/antifolates; structure-function and regulation of the proton-coupled folate transporter; homology modeling; role in the activities of antifolates within the acidic microenvironment of epithelial cancers View Profile Walter G. Levine, Ph.D. Professor Emeritus, Department of Molecular Pharmacology 718.430.2174walter.levine@einsteinmed.edu View Profile Charles S. Rubin, Ph.D. Professor Emeritus, Department of Molecular Pharmacology 718.430.2505charles.rubin@einsteinmed.edu View Profile Other Faculty Monica M. Bastos Paoliello, Ph.D. Staff Scientist, Department of Molecular Pharmacology 718.430.4047monica.paoliello@einsteinmed.edu View Profile Pan Chen, Ph.D. Research Associate Professor, Department of Molecular Pharmacology 718.430.4047pan.chen@einsteinmed.edu Areas of Research: Mechanisms of manganese-induced neurotoxicity, manganese transporters and its intracellular regulators, the interaction between genetic and environmental risk factors, bioactive natural small molecules. View Profile Airton Da Cunha Martins, Ph.D. Staff Scientist, Department of Molecular Pharmacology 718.430.4047airton.dacunhamartinsjunior@einsteinmed.edu Areas of Research: Toxicology, Neurotoxicology, metals View Profile Beatriz Ferrer Villahoz, Ph.D. Staff Scientist, Department of Molecular Pharmacology 718.430.7920beatriz.ferrervillahoz@einsteinmed.edu View Profile Omamuyovwi M. Ijomone, Ph.D. Visiting Assistant Professor, Department of Molecular Pharmacology 718.430.4047omamuyovwi.ijomone@einsteinmed.edu Areas of Research: Metal neurotoxicity; developmental neurotoxicity; mechanisms of neurodegeneration; gene-environment interactions and gut microbiome modulation in brain disorders; environmental toxicology View Profile Kai Mao, Ph.D. Research Assistant Professor, Department of Molecular Pharmacology 718.839.7964kai.mao@einsteinmed.edu Areas of Research: Aging biology, Pharmaceutically intervention against aging especially in cardiovascular system View Profile Ji Ying Sze, Ph.D. Associate Professor, Department of Molecular Pharmacology 718.430.2084jiying.sze@einsteinmed.edu Areas of Research: Regulatory mechanisms of early postnatal cortical gene expression in neural circuit development and psychiatric disorders, with a focus on the role of serotonin uptake transporter and early life drug exposure. View Profile Chia-Ping H. Yang, Ph.D. Instructor, Department of Molecular Pharmacology 718.430.2192chia-ping.h.yang@einsteinmed.edu View Profile