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Kao YR, Chen J, Kumari R, Ng A, Zintiridou A, Tatiparthy M, Ma Y, Aivalioti MM, Moulik D, Sundaravel S, Sun D, Reisz JA, Grimm J, Martinez-Lopez N, Stransky S, Sidoli S, Steidl U, Singh R, D'Alessandro A, Will B.
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Regulation of the mobilizable hematopoietic stem cell pool by c-Kit-mediated trogocytosis.
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An iron rheostat controls hematopoietic stem cell fate.
Cell Stem Cell 2024
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Okoye-Okafor UC, Javarappa KK, Tsallos D, Saad J, Yang D, Zhang C, Benard L, Thiruthuvanathan VJ, Cole S, Ruiz S, Tatiparthy M, Choudhary G, DeFronzo S, Bartholdy BA, Pallaud C, Ramos PM, Shastri A, Verma A, Heckman CA, Will B.
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Aivalioti MM, Bartholdy BA, Pradhan K, Bhagat TD, Zintiridou A, Jeong JJ, Thiruthuvanathan VJ, Pujato M, Paranjpe A, Zhang C, Levine RL, Viny AD, Wickrema A, Verma A, Will B.
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Megakaryopoiesis impairment through acute innate immune signaling activation by azacitidine.
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PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation.
Blood Cancer Discovery 2022
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Dong S, Wang Q, Kao YR, Diaz A, Tasset I, Kaushik S, Thiruthuvanathan V, Zintiridou A, Nieves E, Dzieciatkowska M, Reisz JA, Gavathiotis E, D'Alessandro A, Will B* and Cuervo AM*. [* co-corresponding authors]
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Chaperone-mediated autophagy sustains haematopoietic stem-cell function.
Nature 2021
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Thrombopoietin receptor-independent stimulation of hematopoietic stem cells by eltrombopag.
Science Translational Medicine 2018
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Will B*, Vogler TO, Narayanagari S, Bartholdy B, Todorova TI, da Silva Ferreira M, Chen J, Yu Y, Mayer J, Barreyro L, Carvajal L, Neriah DB, Roth M, van Oers J, Schaetzlein S, McMahon C, Edelmann W, Verma A, Steidl U*. [* co-corresponding authors]
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Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.
Nature Medicine 2015
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