Despite tremendous progress, exact mechanism of hospital transmission of infections remans uncertain.  My research interest lies in understanding mechanism of transmisison of Clostridioides difficile in acute care setting.  Specifically, I would like to understand spatio-temporal factors involved in Clostridioides difficile acquisition and transmission, and apply process improvement methodology to limit HAI trasnmission.  I am also interested in leveraging EMR data and healthcare informatics tools to improve early recognition and management of sepsis. 

My clinical infectious diseases interest lies is preventing, treating and managing infections with patients with immune-mediated inflammatory disease (IMID), including patients with primary and secondary immunedeficiencies as well as drug induced immune dysregulation. 

Gendlina I, Held KG, Bartra SS, Gallis BM, Doneanu CE, Goodlett DR, Plano GV, Collins CM. Identification and type III-dependent secretion of the Yersinia pestis insecticidal-like proteins. Mol Microbiol. 2007 Jun;64(5):1214-27. PubMed PMID: 17542916.

Gendlina I. Identification and Characterization of a Yersinia pestis insecticidal-like toxin complex. Miami: University of Miami; 2006. 229p

Gendlina I, Gutman DM, Thomas V, Collins CM. Urea-dependent signal transduction by the virulence regulator UreR. J Biol Chem. 2002 Oct 4;277(40):37349-58. PubMed PMID: 12147687.

Ames RY, Ting LM, Gendlina I, Kim K, Macian F. The Transcription Factor NFAT1 Participates in the Induction of CD4⁺ T Cell Functional Exhaustion during Plasmodium yoelii Infection. Infect Immun. 2017 Sep;85(9)PubMed PMID: 28630062; PubMed Central PMCID: PMC5563568.

Gendlina I, Silmon de Monerri N, Kim K. Modification of the Host Epigenome by Parasitic Protists. Springer series on Epigenetics and Human Health. 2017