![Nitin P. Amdare](https://assets.montefioreeinstein.org/profiles/images/15208-nitin-amdare.jpg)
Nitin P. Amdare, Ph.D.
- Staff Scientist, Department of Microbiology & Immunology
Area of research
- Immunology, Autoimmunity, Type 1 diabetes
Phone
Location
- Albert Einstein College of Medicine Jack and Pearl Resnick Campus 1300 Morris Park Avenue Forchheimer Building 403 Bronx, NY 10461
Research Profiles
Selected Publications
· Amdare N, Purcell AW, DiLorenzo TP. Non-contiguous T cell epitopes in autoimmune diabetes: From mice to men and back again. J Biol Chem. 2021 May 24:100827. DOI: 10.1016/j.jbc.2021.100827. Epub ahead of print. PMID: 34044020.
· Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Characterization, and use of human insulin transgenic mouse models for type 1 diabetes. J Immunol, 201 (2020), p. 142, 14
· Khatri V, Amdare N, Chauhan N, Togre N, Reddy MV, Hoti SL, Kalyanasundaram R. Epidemiological screening and xenomonitoring for human lymphatic filariasis infection in select districts in the states of Maharashtra and Karnataka, India. Parasitol Res. 2019 Mar;118(3):1045-1050. doi: 10.1007/s00436-019-06205-0. Epub 2019 Jan 21. PMID: 30666407.
· Paul R, Ilamaran M, Khatri V, Amdare N, Reddy MVR, Kaliraj P. Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model. Parasite Epidemiol Control. 2019 Feb 7;4:e00092. doi: 10.1016/j.parepi.2019.e00092. PMID: 30847408; PMCID: PMC6378782.
· Togre N, Bhoj P, Amdare N, Goswami K, Tarnekar A, Shende M. Immunomodulatory potential of recombinant filarial protein, rWbL2, and its therapeutic implication in experimental ulcerative colitis in mouse. Immunopharmacol Immunotoxicol. 2018 Dec;40(6):483-490. doi: 10.1080/08923973.2018.1431925. Epub 2018 Feb 7. PMID: 29411665.
· Immanuel C, Ramanathan A, Balasubramaniyan M, Khatri VK, Amdare NP, Rao DN, Reddy MVR, Perumal K. Immunoprophylaxis of multi-antigen peptide (MAP) vaccine for human lymphatic filariasis. Immunol Res. 2017 June ;65(3):729-738. doi: 10.1007/s12026-017-8911-5. PMID: 28432603.
· Amdare NP, Khatri VK, Yadav RSP, Tarnekar A, Goswami K, Reddy MVR. Therapeutic potential of the immunomodulatory proteins Wuchereria bancrofti L2 and Brugia malayi abundant larval transcript 2 against streptozotocin-induced type 1 diabetes in mice. J Helminthol. 2017 Sep ;91(5):539-548. doi: 10.1017/S0022149X1600064X. Epub 2016 Sep 26. PMID: 27667321.
· Reddy SM, Reddy PM, Amdare N, Khatri V, Tarnekar A, Goswami K, Reddy MVR. Filarial Abundant Larval Transcript Protein ALT-2: An Immunomodulatory Therapeutic Agent for Type 1 Diabetes. Indian J Clin Biochem. 2017 Mar;32(1):45-52. doi: 10.1007/s12291-016-0572-y. Epub 2016 Jun 7. PMID: 28149012.
· Yadav RS, Khatri V, Amdare N, Goswami K, Shivkumar VB, Gangane N, Reddy MVR. Evaluation of preventive effect of Brugia malayi recombinant cystatin on antigen-induced experimental arthritis. Ind J exp Biochem. 2016; 55:(655-660).
· Andure D, Pote K, Khatri V, Amdare N, Padalkar R, Reddy MV. Immunization with Wuchereria bancrofti Glutathione-S-transferase Elicits a Mixed Th1/Th2 Type of Protective Immune Response Against Filarial Infection in Mastomys. Indian J Clin Biochem. 2016 Oct;31(4):423-30. doi: 10.1007/s12291-016-0556-y. Epub 2016 Feb 9. PMID: 27605739.
· Andure D, Reddy MV, Pote K, Padalkar R, Khatri V, Amdare N. Role of recombinant SXP/RAL-2 family protein Wuchereria bancrofti L2 (rWbL2) as vaccine candidate in lymphatic filariasis in mastomys. International Journal of Research in Medical Sciences. 2016 Apr;4(4):1140.
· Amdare N, Khatri V, Yadav RS, Tarnekar A, Goswami K, Reddy MV. Brugia malayi soluble and excretory-secretory proteins attenuate development of streptozotocin-induced type 1 diabetes in mice. Parasite Immunol. 2015 Dec;37(12):624-34. doi: 10.1111/pim.12283. PMID: 26434489.
· Khatri V, Amdare N, Tarnekar A, Goswami K, Reddy MV. Brugia malayi cystatin therapeutically ameliorates dextran sulfate sodium-induced colitis in mice. J Dig Dis. 2015 Oct;16(10):585-94. doi: 10.1111/1751-2980.12290. PMID: 26358507.
·. Khatri V, Amdare N, Yadav RS, Tarnekar A, Goswami K, Reddy MV. Brugia malayi abundant larval transcript 2 protein treatment attenuates experimentally induced colitis in mice. Indian J Exp Biol. 2015 Nov;53(11):732-9. PMID: 26669016.
· Yadav RS, Khatri V, Amdare N, Goswami K, Shivkumar VB, Gangane N, Reddy MV. Immuno-Modulatory Effect and Therapeutic Potential of Brugia malayi Cystatin in Experimentally Induced Arthritis. Indian J Clin Biochem. 2016 Apr;31(2):203-8. doi: 10.1007/s12291-015-0515-z. Epub 2015 Jul 23. PMID: 27069328;
· Anugraha G, Madhumathi J, Prince PR, Prita PJ, Khatri VK, Amdare NP, Reddy MV, Kaliraj P. Chimeric Epitope Vaccine from Multistage Antigens for Lymphatic Filariasis. Scand J Immunol. 2015 Oct;82(4):380-9. doi: 10.1111/sji.12340. PMID: 26179420.
· Aparnaa R, Mahalakshmi N, Harini A, Jeyaprita PJ, Anugraha G, Amdare NP, Khatri VK, Reddy MV, Kaliraj P. Wuchereria bancrofti 20/22 a homologue of abundant larval transcript L3 stage filarial antigen: molecular and immunological characterization. Parasite Immunol. 2014 Oct;36(10):475-84. doi: 10.1111/pim.12120. PMID: 24888320.