The invariant component of the SWI/SNF chromatin remodeling complex INI1/SMARCB1/hSNF5/BAF47 is involved in different cellular functions, like, transcription, cell cycle regulation, development, and tumor suppression. Host INI1 and the viral HIV-1 integrase (IN) are required at different stages of HIV-1 infection. The Rpt1 domain of INI1 binds to the C-terminal domain of HIV-1 IN. In fact, INI1-Rpt1 and HIV-1 TAR RNA compete with each other for HIV-1 IN binding as evident from the common residues involved in both these biomolecular interactions. Interestingly, the three-dimensional structure of INI1-Rpt1 domain, despite being part of a protein, shares a close resemblance with HIV-1 TAR RNA. This structural semblance between a host protein and the viral RNA is rather intriguing and raises several interesting questions regarding the host-pathogen cross talk during HIV-1 infection. We are interested in understanding the rationale behind this evolutionary arrangement for a possible modulation of the interaction between the human host and HIV-1 virus, and in the process, identify potential anti-HIV therapeutic targets.

2023

1.     Acharya Balkrishna, Bhawana Kharayat, Shubhangi Rastogi, Manisha Kabdwal, Swati Haldar* and Anurag Varshney* (2023) Withania somnifera Seed Oil Exhibits Anti-biofilm Properties Against Drug-resistant Candida auris Clinical Isolate Through Modulation in Cell Permeability. Journal of Applied Microbiology. (Accepted) *Co-corresponding author (IF 4.061)

2.     Acharya Balkrishna, Swati Haldar and Anurag Varshney (2023) OECD-407 Driven 28-day-repeated-dose non-clinical safety evaluation of Tinospora cordifolia (Giloy) stem aqueous extract in Sprague-Dawley rats under GLP compliance. Frontiers in Pharmacology. (Accepted) (IF 5.810)

3.     Acharya Balkrishna, Sohan Sengupta, Priya Kumari, Rishabh Dev, Swati Haldar, Anurag Varshney (2023) Anu Taila, an Herbal Nasal-drop, Delays Spore Germination in Cunninghamella bertholletiae by Reducing cAMP-PKA dependent ROS in Mucorale Pathogen and Extrinsic ROS in Human Host Cells. Letters in Applied Microbiology. 76: ovad014. doi: 10.1093/lambio/ovad014. (IF 2.85)

4.     Viney Kumar, Swati Haldar, Saakshi Saini, Souvik Ghosh, Poonam Dhankhar, Partha Roy (2023) Pterostilbene–isothiocyanate reduces miR‑21 level by impeding Dicer‑mediated processing of pre‑miR‑21 in 5‑fuorouracil and tamoxifen‑resistant human breast cancer cell lines. 3 Biotech 13:193. doi: 10.1007/s13205-023-03582-3.

2022

5.     Acharya Balkrishna, Shubhangi Rastogi, Bhawana Kharayat, Meenu Tomer, Yash Varshney, Kanchan Singh, Priya Kumari, Rishabh Dev, Jyotish Srivastava, Swati Haldar*, Anurag Varshney* (2022) Anu taila, an herbal nasal drop, suppresses mucormycosis by regulating host TNF-α response and fungal ergosterol biosynthesis. Journal of Applied Microbiology. 132: 3355-3374. doi: 10.1111/jam.15451. *Co-corresponding author (IF 4.061)

6.     Souvik Ghosh*, Swati Haldar*, Sumeet Gupta, Samrat Chauhan, Vishal Mago, Partha Roy, Debrupa Lahiri (2022) Single unit functionally gradient bioresorbable electrospun scaffold with commercial potential for full thickness (severe) wound healing. Biomaterials Advances (Accepted) (IF 7.32) * Co-first author.

7.       Swati Haldar, Himanshu Agrawal, Sarama Saha, Alex R Straughn, Partha Roy, Sham S Kakar. (2022) Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells. International Journal of Biological Sciences. 18: 675-692. doi: 10.7150/ijbs.63721. (IF 6.58)

8.       Acharya Balkrishna, Sudeep Goswami, Hoshiyar Singh, Vivek Gohel, Rishabh Dev, Swati Haldar, Anurag Varshney*. (2022) Herbo-Mineral Formulation, Divya-Swasari-Vati Averts SARS-CoV-2 pseudovirus Entry into Human Alveolar Epithelial Cells by Interfering with Spike Protein-ACE 2 Interaction and IL-6/TNF-a /NF-kB Signaling. Frontiers in Pharmacology. 13:1024830. doi: 10.3389/fphar.2022.1024830. (IF 5.810)

9.       Viney Kumar, Swati Haldar, Souvik Ghosh, Samrat Chauhan, Abhishek Sharma, Poonam Dhankhar, Amit Kumar, Satish Jaiswal, Saakshi Saini, Sumeet Gupta, Debrupa Lahiri, Partha Roy. (2022) Pterostilbene-isothiocyanate impedes RANK/TRAF6 interaction to inhibit osteoclastogenesis, promoting osteogenesis in vitro and alleviating glucocorticoid induced osteoporosis in rats. Biochemical Pharmacology. (Accepted). (IF 5.858)

10.  Acharya Balkrishna, Sudeep Verma, Vallabh Prakash Mulay, Ashish Kumar Gupta, Swati Haldar, Anurag Varshney (2022) Withania somnifera (L.) Dunal Whole-plant Extracts Exhibited Anti-Sporotrichotic Effects by Destabilizing Peripheral Integrity of Sporothrix globosa Yeast Cells. PLOS Neglected Tropical Diseases 16(6): e0010484. doi: org/10.1371/journal.pntd.0010484. (IF 4.411)

11.  Acharya Balkrishna, Sandeep Sinha, Shadrak Karumuri, Jyotish Srivastava, Swati Haldar, Anurag Varshney (2022) Peedanil Gold, Herbo-Mineral Formulation, Moderates Cytokine Levels and Attenuates Pathophysiology in Monosodium Iodoacetate Induced Osteoarthritis in SD Rat Model. Frontiers in Pharmacology. 13: 883475. doi: 10.3389/fphar.2022.883475. (IF 5.810)

12.    Acharya Balkrishna, Shadrak Karumuri, Sachin S Sakat, Swati Haldar, Anurag Varshney (2022) Anti-oxidant profile of Divya-Peedantak-Vati abates paclitaxel-induced hyperalgesia and allodynia in CD-1 mice model of neuropathic pain. Phytomedicine Plus. 2: 100229. doi: 10.1016/j.phyplu.2022.100229. (IF 3.0)

13.    Acharya Balkrishna, Kunal Bhattacharya, Sandeep Sinha, Rishabh Dev, Jyotish Srivastava, Pratima Singh, Swati Haldar, Anurag Varshney (2022) Apparent Hepatotoxicity of Giloy (Tinospora cordifolia): Far From What Meets the Eyes. Journal of Clinical and Experimental Hepatology. 12: 239-240. doi: 10.1016/j.jceh.2021.09.009. (IF 1.56)

14.    Acharya Balkrishna, Swami Yagyadev, Swami Vipradev, Kanchan Singh, Yash Varshney, Shubhangi Rastogi, Swati Haldar, Anurag Varshney (2022) Vishaghn Dhoop, Nano-Scale Particles with Detoxifying Medicinal Fume, Exhibits Robust Anti-Microbial Activities: Implications of Disinfection Potentials of a Traditional Ayurvedic Air Sterilization Technique. Journal of Evidence-Based Integrative Medicine. 27: 1-15. (IF 2.22)

15.  Kanike Rajesh, Souvik Ghosh, Aminul Islam, Manoj Kumar Rangaswamy, Swati Haldar, ParthaRoy, Anup Kumar Keshri, Debrupa Lahiri (2022) Multilayered porous hydroxyapatite coating on Ti6Al4V implant with enhanced drug delivery and antimicrobial properties. Journal of Drug Delivery Science and Technology. 70: 103155. doi: 10.1016/j.jddst.2022.103155. (IF 3.981)

16.  Acharya Balkrishna, Kanchan Singh, Swati Haldar, Anurag Varshney (2022) Germi-X herbal-based spray disinfects smartphone surfaces: implication on fomite-mediated infection spread. AMB Express. 12: 30. doi: 10.1186/s13568-022-01369-y (IF 3.298)

2021

17.    Acharya Balkrishna, Subarna Pokhrel, Hoshiyar Singh, Monali Joshi, Vallabh Mulay, Swati Haldar*, Anurag Varshney*. (2021) Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish Model. Drug Design Development and Therapy. 15: 1111–1133. doi: 10.2147/DDDT.S292805. *Co-corresponding author (IF 4.162)

18.    Viney Kumar, Swati Haldar, Neeladri Singha Das, Souvik Ghosh, Poonam Dhankhar, Debabrata Sircar, Partha Roy. (2021) Pterostilbene-isothiocyanate inhibits breast cancer metastasis by selectively blocking IKK-β/NEMO interaction in cancer cells. Biochemical Pharmacology. 192: 114717. doi: 10.1016/j.bcp.2021.114717. (IF 5.858)

19.    Acharya Balkrishna, Meenu Tomer, Moumita Manik, Jyotish Srivastava, Rishabh Dev, Swati Haldar, Anurag Varshney. (2021) Chyawanprash, An Ancient Indian Ayurvedic Medicinal Food, Regulates Immune Response in Zebrafish Model of Inflammation by Moderating Inflammatory Biomarkers. Frontiers in Pharmacology. 12:751576. doi: 10.3389/fphar.2021.751576. (IF 5.810)

20.    Acharya Balkrishna, Ashish Kumar Gupta, Kanchan Singh, Swati Haldar, Anurag Varshney. (2021) Effects of fatty acids in super critical fluid extracted fixed oil from Withania somnifera seeds on Gram-negative Salmonella enterica biofilms. Phytomedicine Plus. 1: 100047. doi: 10.1016/j.phyplu.2021.100047. (IF 3.0)

21.    Acharya Balkrishna, Swati Haldar, Hoshiyar Singh, Partha Roy, Anurag Varshney. (2021) Coronil, A Tri-herbal Formulation, Attenuates Spike-protein Mediated SARS-CoV-2 Viral entry into Human Alveolar Epithelial Cells and Pro-inflammatory Cytokines Production by Inhibiting Spike protein-ACE-2 Interaction. Journal of Inflammation Research. 14: 869–884. doi: 10.2147/JIR.S298242 (IF 6.922)

22.    Ganpat Devpura, Balvir S. Tomar, Deepak Nathiya, Abhishek Sharma, Deepak Bhandari, Swati Haldar, Acharya Balkrishna, Anurag Varshney. (2021) Randomized Placebo-Controlled Pilot Clinical Trial on the Efficacy of Ayurvedic Treatment Regime on COVID-19 Positive Patients. Phytomedicine. 84:153494. doi: 10.1016/j.phymed.2021.153494 (IF 5.34)

23.    Acharya Balkrishna, Aarti Ben Bhatt, Pratima Singh, Swati Haldar, Anurag Varshney. (2021) Comparative retrospective open-label study of ayurvedic medicines and their combination with allopathic drugs on asymptomatic and mildly-symptomatic COVID-19 patients. Journal of Herbal Medicine. 29: 100472. doi: 10.1016/j.hermed.2021.100472. (IF 3.032)

24.    Suchita Srivastava, Satinderdeep Kaur, Hemant K. Verma, SumanRani, Manisha Thakur, Swati Haldar, Jagmohan Singh. (2021) Reciprocal relation between reporter gene transcription and translation efficiency in fission yeast. Plasmid. 115: 102557. doi: 10.1016/j.plasmid.2021.102557. (IF 3.466)

2020

25.    Acharya Balkrishna, Kanchan Singh, Hoshiyar Singh, Swati Haldar and Anurag Varshney. (2020) GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria. AMB Express. 10: 210. doi: 10.1186/s13568-020-01151-y (IF 3.298)

26.    Acharya Balkrishna, Sachin S. Sakat, Shadrak Karumuri, Hoshiyar Singh, Meenu Tomer, Ajay Kumar, Niti Sharma, Pradeep Nain, Swati Haldar and Anurag Varshney. (2020) Herbal Decoction Divya-Peedantak-Kwath Alleviates Allodynia and Hyperalgesia in Mice Model of Chemotherapy-Induced Peripheral Neuropathy via Modulation in Cytokine Response. Frontiers in Pharmacology. 11: 566490. doi: 10.3389/fphar.2020.566490. (IF 5.810)

27.    Souvik Ghosh*, Swati Haldar*, Sumeet Gupta, Ankita Bisht, Samrat Chauhan, Viney Kumar, Partha Roy and Debrupa Lahiri. (2020) An Anisotropically Conductive Biodegradable Scaffold with Co-Axially Aligned Carbon Nanotubes for Directional Regeneration of Peripheral Nerves. ACS Applied Bio Materials. 3: 5796–5812. doi: 10.1021/acsabm.0c00534. (*equal contribution). (IF 3.25)

28.    Anshu Dubey, Satish Jaiswal, Swati Haldar, Partha Roy and Debrupa Lahiri. (2020) Functionally gradient magnesium-based composite for temporary orthopedic implant with improved corrosion resistance and osteogenic properties. Biomedical Materials. 16: 015017. doi: 10.1088/1748-605X/abb721. (IF 3.987)

29.    Swarnima Singh, Krishna Kant Pandey, OS Asiq Rahman, Swati Haldar, Debrupa Lahiri and Anup Kumar Keshri. (2020) Investigation of crystallinity, mechanical properties, fracture toughness and cell proliferation in plasma sprayed graphene nano platelets reinforced hydroxyapatite coating. Materials Research Express. 7: 015415. doi: 10.1088/1748-605X/abb721. (IF 1.620)

2019

30.    Swati Haldar, Souvik Ghosh, Viney Kumar, Partha Roy and Debrupa Lahiri. (2019) The Evolving Neural Tissue Engineering Landscape of India. ACS Applied Bio Materials. 2: 5446–5459. doi: 10.1021/acsabm.9b00567. (IF 3.25)

31.    Swati Haldar, Akriti Sharma, Sumeet Gupta, Samrat Chauhan, Partha Roy and Debrupa Lahiri. (2019) Bioengineered smart trilayer skin tissue substitute for efficient deep wound healing. Materials Science and Engineering: C. 105: 110140. doi: 10.1016/j.msec.2019.110140 (IF 7.328)

32.    Satish Jaiswal, Anshu Dubey, Swati Haldar, Partha Roy and Debrupa Lahiri. (2019) Differential in-vitro degradation and protein adhesion behaviour of SPS fabricated magnesium based temporary orthopaedic implant in serum and simulated body fluid. Biomedical Materials. 15: 015006. doi: 10.1088/1748-605X/ab4f8b. (IF 3.987)

33.    Kanike Rajesh, Manoj Kumar Rangaswamy, Cheng Zhang, Swati Haldar, Murali Kumarasamy, Arvind Agarwal, Partha Roy and Debrupa Lahiri. (2019) Surface Modified Metallic Orthopedic Implant for Sustained Drug Release and Osteocompatibility. ACS Applied Bio Materials. 2: 4181−4192. doi: 10.1021/acsabm.9b00443. (IF 3.25)

34.    Manoj Kumar Rangaswamy, Swati Haldar, Kanike Rajesh, Souvik Ghosh and Debrupa Lahiri. (2019) Comparative study on the efficacy of the UHMWPE surface modification by chemical etching and electrostatic spraying method for drug release by orthopedic implants. Materials Science and Engineering: C.105:110117. doi: 10.1016/j.msec.2019.110117. (IF 7.328)

35.    Manoj Kumar Rangaswamy, Kanike Rajesh, Swati Haldar, Pallavi Gupta, K. Murali, Partha Roy and Debrupa Lahiri. (2019) Surface modification of CNT reinforced UHMWPE composite for sustained drug delivery. Journal of Drug Delivery Science and Technology. 52: 748-759. doi: 10.1016/j.jddst.2019.05.044. (IF 3.981)

36.    Anshu Dubey, Satish Jaiswal, Swati Haldar, Partha Roy, Debrupa Lahiri. (2019) Mg-3Zn/HA Biodegradable Composites Synthesized via Spark Plasma Sintering for Temporary Orthopedic Implants. Journal of Materials Engineering and Performance, 28:5702-5715. doi: 10.1007/s11665- 019-04315-5. (IF 1.819)

2015

37.    Swati Haldar, Ajai K. Tripathi, Juan Qian, Amber Beserra, Srinivas Suda S, Matthew McElwee, Jerrold Turner, Ulrich Hopfer and Neena Singh. (2015) Prion Protein Promotes Kidney Iron Uptake via its Ferrireductase Activity. Journal of Biological Chemistry. 290; 5512-5522. doi: 10.1074/jbc.M114.607507. (IF 5.157)

38.    Ajai K. Tripathi*, Swati Haldar*, Juan Qian, Amber Beserra, Srinivas Suda S, Ajay Singh, Ulrich Hopfer, Shu G. Chen, Michael D. Garrick, Jerrold R. Turner, Mitchell D. Knutson, Neena Singh. (2015) Prion protein functions as a ferrireductase partner for ZIP14 and DMT1. Free Radical Biology and Medicine. 84: 322-330. doi: 10.1016/j.freeradbiomed.2015.03.037. (*equal contribution). (IF 7.376)

39.    Neena Singh, Abhishek Asthana, Shounak Baksi, Vilok Desai, Swati Haldar, Sahi Hari and Ajai K. Tripathi. (2015) The prion-ZIP connection: From cousins to partners in iron uptake. Prion. 9: 420- 428. doi: 10.1080/19336896.2015.1118602. (IF 3.931)

40.    Poonam Shukla, Balveer Singh, Ashok Saini, Jyotsna, Swati Haldar and Jagmohan Singh. (2015) Efficient PCR-based epitope gene tagging in Schizosaccharomyces pombe. Current Science. 110: 146-148. (IF 1.102)

2014

41.    Neena Singh, Swati Haldar, Ajai K. Tripathi, Matthew K. McElwee, Katherine Horback and Amber Beserra. (2014) Iron in Neurodegenerative Disorders of Protein Misfolding: A Case of Prion Disorders and Parkinson's Disease. Antioxidant & Redox Signaling. 21; 471-484. doi: 10.1089/ars.2014.5874. (IF 7.040)

42.    Neena Singh, Swati Haldar, Katy Horback, Joseph Wong, Deepak Sharma, Amber Bessera, Srinivas Suda, Chinmay Mukhopadhyay, Ajay Singh and Som Dev. (2014) Brain Metal Homeostasis: From Molecular Mechanisms to Clinical Significance and Therapeutic Opportunities (Comprehensive Invited Review). Antioxidant & Redox Signaling. 20: 1324-1363. doi: 10.1089/ars.2012.4931. (IF 7.040)

2013

43.    Swati Haldar, Alim J. Beveridge, Joseph Wong, Ajay Singh, Daniela Galimberti, Barbara Borroni, Xiongwei Zhu, Janis Blevins, Justin Greenlee, George Perry, Chinmay K. Mukhopadhyay, Christine Schmotzer and Neena Singh. (2013) A Low-Molecular-Weight Ferroxidase Is Increased in the CSF of sCJD Cases: CSF Ferroxidase and Transferrin as Diagnostic Biomarkers for sCJD. Antioxidant & Redox Signaling. 19: 1662-1675. doi: 10.1089/ars.2012.5032. (IF 7.040)

44.    Ajay Singh, Swati Haldar, Katy Horback, Cynthia Tom, Lan Zhou, Stephanie Booth, Howard Meyerson, and Neena Singh. (2013) Prion Protein Regulates Iron Transport by Functioning as a Ferrireductase. Journal of Alzheimers Disease. 35:541-552. doi: 10.3233/JAD-130218. (IF 4.472)

2011

45.    Swati Haldar, Ashok Saini, Jagpreet Singh Nanda, Sharanjot Saini and Jagmohan Singh. (2011) Role of Swi6/HP1 self-association-mediated recruitment of Clr4/Suv39 in Establishment and Maintenance of Heterochromatinin Fission Yeast. Journal of Biological Chemistry. 286: 9308-9320. doi: 10.1074/jbc.M110.143198. (IF 5.157)

2010

46.    Ranjana Tripathi, Santa Singh Naorem, Chetna Dureja, Swati Haldar, Alok K. Mondal and Saumya Raychaudhuri. (2010) VopF, atype III effector protein from a non-O1, non-O139 Vibrio cholera strain, demonstrates toxicity in a Saccharomyces cerevisiae model. Journal of Medical Microbiology.59:17- 24. doi: 10.1099/jmm.0.012336-0. (IF 2.156)

2009

47. Rudra Narayan Dubey, Nandni Nakwal, Kamlesh Kumar Bisht, Ashok Saini, Swati Haldar and Jagmohan Singh (2009) Interaction of APC/C-E3 Ligase with Swi6/HP1 and Clr4/Suv39 in Heterochromatin Assembly in Fission Yeast. (selected as the paper of the week). Journal of Biological Chemistry. 284: 7165-7176. doi: 10.1074/jbc.M806461200. (IF 5.157)