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Wei Q, Pinho S, Dong S, Pierce H, Li H, Nakahara F, Xu J, Xu C, Boulais PE, Zhang D, Maryanovich M, Cuervo AM, Frenette PS.
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.
Nat Commun.
2021 May 4;12(1):2522.
Tchernychev B, Li H, Lee SK, Gao X, Ramanarasimhaiah R, Liu G, Hall KC, Bernier SG, Jones JE, Feil S, Feil R, Buys ES, Graul RM, Frenette PS, Masferrer JL.
Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease.
Br J Pharmacol.
2021 Apr 17. doi: 10.1111/bph.15492. Online ahead of print.
Zahalka AH, Brodin NP, Maryanovich M, Wang X, Watts KL, Pinho S, Guha C, Frenette PS.
Using CT-guided stereotactic prostate radiation therapy (CT-SPRT) to assess sustained murine prostate ablation.
Sci Rep.
2021 Mar 22;11(1):6571.
Renders S, Svendsen AF, Panten J, Rama N, Maryanovich M, Sommerkamp P, Ladel L, Redavid AR, Gibert B, Lazare S, Ducarouge B, Schönberger K, Narr A, Tourbez M, Dethmers-Ausema B, Zwart E, Hotz-Wagenblatt A, Zhang D, Korn C, Zeisberger P, Przybylla A, Sohn M, Mendez-Ferrer S, Heikenwälder M, Brune M, Klimmeck D, Bystrykh L, Frenette PS, Mehlen P, de Haan G, Cabezas-Wallscheid N, Trumpp A.
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.
Nat Commun.
2021 Jan 27;12(1):608.
Gao X, Zhang D, Xu C, Li H, Caron KM, Frenette PS.
Nociceptive nerves regulate haematopoietic stem cell mobilization.
Nature
. 2021 Jan;589(7843):591-596.
Xu C, Gulinello M, Frenette PS.
Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage.
J Exp Med.
2021 Jan 4;218(1).