| Study Name |
Investigators and Roles |
Project Type |
| Current Projects |
| Investigating Dupilumab’s Effect in Asthma by genotype (IDEA) |
Sunit Jariwala, MD (Site PI)
Andrew Telzak, MD MSc (Site Co-I) |
Phase IV Clinical Trial |
| The main objective of this trial is to study if individuals ages 12 years and older, carrying the IL-4RαR576 gene variant, will have a greater response to therapy acting directly on the anti-IL-4R (via a 48-week exposure to Dupilumab). |
| Implementation of a Centralized Screening Unit to Increase Lung Cancer Screening and Downstage Tumors in an Urban Minority Population |
Dean Hosgood PhD (PI)
Andrew Telzak MD MSc (Co-I) |
Implementation Study (Multisite) |
| This research aims to study the extent/degree of full implementation of a centralized screening unit for lung cancer screening, to assess its impact on lung cancer screening referral rates in minoritized and low-income communities, and to determine the ‘success’ of the screening unit as measured by extent of ‘down-staging’ of lung cancer tumor stage at diagnosis. |
| NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation Randomized Controlled Trial (NYC CONNECT) |
Bruce Rapkin, PhD (mPI)
Andrew Telzak, MD MSc (Co-I) |
Randomized Controlled Trial |
| This study aims to assess the relative effectiveness of two evidence-based strategies to increase cancer screening rates for Breast, Colorectal and Cervical cancer, comparing enhanced usual care (with cancer screening education) with a patient navigation strategy to connect patients to cancer screening and address unmet social needs. |
| Penicillin Allergy De-labeling Initiative |
Chris Oh, MD (PI),
Andrew Telzak, MD MSc (Co-I) |
Pilot Implementation Study |
| This study aims to study the implementation of penicillin oral challenge protocols in the primary care setting, with the goal of delabeling penicillin allergies from patients incorrectly assigned an allergy in the Electronic Medical Record. |
| Redesigning Home Physical Therapy: Home Physical Therapy Regimen for Rotator Cuff Injuries |
Andrew Telzak, MD MSc (PI)
Olutimilehin Oyeniran MD (Co-I) |
Pilot Implementation Study |
| This study investigates the feasibility and effectiveness of an at-home physical therapy program for patients with rotator cuff injuries and multiple barriers to accessing traditional office-based physical therapy. |
| 5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care (5-Cog 2.0) |
Joe Verghese, MBBS MS (PI)
Andrew Telzak, MD MSc (Co-I) |
Pragmatic Clinical Trial
NIA |
| This study uses a hybrid Type 1 effectiveness-implementation design to test the 5-cog paradigm of cognitive assessment paired with clinical decision-making support in a pragmatic, cluster randomized trial across 22 primary care sites in the Bronx and Indiana. |
| The goal of this study was to develop and validate a 5-minute cognitive screen coupled with a decision tree to identify and manage persons at high risk of developing dementia in multi-ethnic primary care populations with socio-economic challenges. |
| Pragmatic
Evaluation of Events And Benefits of
Lipid lowering in older Adults (PREVENTABLE) |
Carlos Rodriguez, MD (Site PI)
Andrew Telzak, MD MSc (Co-I)
|
Pragmatic Clinical Trial
(Multisite) |
| PREVENTABLE is a multi-center, randomized, parallel group,
placebo-controlled superiority study among community-dwelling older adults without cardiovascular
disease (CVD) or
dementia with the aim of demonstrating the benefit of statins for reducing the primary composite of
death, dementia, and persistent disability and secondary composites including mild cognitive
impairment (MCI) and cardiovascular events. |
| Enhancing the Community
Health Worker (CHW) Model to
Promote Diabetes Technology Use in Young Adults from Underrepresented Minority Groups (YA-URMs) with Type 1 Diabetes (T1D) (CATCH - T1D) |
Shivani Agarwal, MD (PI)
Andrew Telzak, MD MSc (Co-I) |
Randomized Clinical Trial |
| The objective of this study is to test the early effects and implementation of an
enhanced community health worker (CHW) model (T1D-CATCH) that encourages and supports diabetes
technology use in young adults from underrepresented minority groups (YA-URMs) with type 1 diabetes
(T1D). |
| Goals for Eating and Moving (GEM) is a 12-month weight management study for
patients seen by primary care teams at the Veterans Affairs and Montefiore Medical Group
sites. |
| Study Name |
Investigators and Roles |
Project Type |
| Past Projects |
| Testing the Efficacy
of a Technology- Assisted Weight
Management Intervention within
Patient-Centered Medical Homes:
The GEM (Goals for Eating and
Moving) Study |
Judith Wylie-Rosett, Ed.D (Site PI)
Paul Meissner, MSPH (NYC RING Liaison) |
Comparative Effectiveness
Trial (Multisite) |
| 5-COG Battery to Improve Detection and Cognitive Impairment and Dementia |
Joe Verghese, MBBS MS (PI)
Asif Ansari, MD (Co-I) |
Randomized Clinical Trial |
| Patient Empowered
Strategy to Reduce Asthma Morbidity in Highly Impacted Populations (PREPARE) |
Diane McKee, MD MS (Site PI)
Asif Ansari MD (Co-I)
Manuja Mathur MD (Co-I) |
Comparative Effectiveness Trial (Multisite) |
| The goal of this study was to understand whether patient-activated
reliever-triggered inhaled corticosteroid reduced asthma exacerbations in Black and Hispanic
patients. |
| Glycemia Reduction Approaches
in Diabetes: A Comparative Effectiveness Study (GRADE) |
Jill Crandall, MD and Diane McKee, MD
MS, (Site Co-PIs) |
Comparative Effectiveness
Trial (Multisite)
|
| The aim of this trial was to determine which of 4 medications when added to metformin
results in optimal glycemic and patient reported outcomes. (n= 5000 across 38 sites nationwide). |
| Acupuncture Approaches
to Decrease Disparities in Outcomes of Pain Treatment (AADDOPT-2) |
Diane McKee, MD MS and
Ben Kligler, MD MPH (Co-PIs) |
Comparative Effectiveness
Trial
|
| The goal of this project was to compare the effectiveness of group and individual
acupuncture for primary care patients with chronic pain due to osteoarthritis, neck or back pain. |
| Group Acupuncture
Therapy with Modified Yoga for chronic neck,
low back and OA pain in safety net setting for underserved population (GAPYOGA) |
Diane McKee, MD MS,
Ben Kligler, MD MPH and Ray Teets,
MD (MPIs) |
Treatment Study (Multisite)
|
| This study intended to establish the feasibility and effectiveness of acupuncture
delivered in a group setting combined with modified group yoga for patients with chronic
musculoskeletal neck, low back and OA pain in a safety net setting. |
| Childhood Asthma Perception Study (CAPS) |
Jonathan Feldman, PhD (PI |
Treatment Study - Individual
Randomization |
| The goal of this study was to examine the efficacy of Peak Expiratory Flow (PEF)
prediction
with PEF feedback versus control feedback on (1) under-perception of asthma symptoms at home and
assessed in clinic (2) adherence to controller medications and (3) asthma control and emergency
health
care. |
| Developing and
Evaluating an Enhanced Algorithmic Software
Tool
to
Help Manage Asthma (ASTHMA)-Educator Mobile Application for Youth with
Asthma |
Sunit P. Jariwala MD (PI) |
Single Arm Feasibility Trial |
| The goals of this study were (1) to enhance a previously developed ASTHMA-Educator
mobile
health application and (2) to evaluate the effectiveness of the enhanced ASTHMA-Educator
intervention in
comparison to enhanced usual care. |
| Bronx
Ongoing Pediatric Screening (BOPS) in the Medical
Home |
Andrew Racine, MD PhD (PI) |
Quality Improvement Initiative |
| This project sought to improve screening for pediatric preventive care, STIs, mental
health,
developmental assessment and newborn screening in an urban primary care network. |
| Blacks and
Exacerbations on LABA vs. Tiotropium
(BELT) |
Diane McKee, MD MS (Site PI)
Donald Raum, MD (Co-I)
Asif Ansari, MD (Co-I) |
Randomized Clinical Trial
(Multisite) |
| The goal of this study was to understand the role of genetics relative to asthma
medications
and treatment for Black populations. |
| Acupuncture to
Decrease Disparities in Outcomes of Pain
Treatment (ADDOPT) |
Diane McKee, MD MS (PI) |
Quasi- experimental Trial |
| This study assessed feasibility and acceptability of incorporating acupuncture as an adjunct to usual treatment for chronic pain in urban health centers. |
| 5-COG Battery to Improve Detection and Cognitive Impairment and
Dementia |
Joe Verghese, MBBS MS (PI)
Asif Ansari, MD (Co-I) |
Randomized Clinical Trial |
| The goal of this study was to develop and validate a 5-minute cognitive screen coupled with
a decision tree to identify and manage persons at high risk of developing dementia in multi-ethnic
primary care populations with socio-economic challenges. |
