The Human Induced Pluripotent Stem Cell (iPSC) unit is dedicated to the generation, characterization, and application of human iPSC models. The unit provides an integrated end-to-end pipeline for reprogramming somatic cells into pluripotent stem cells and directing their differentiation into physiologically relevant cell types. With a strong focus on quality, reproducibility, and translational relevance, the facility supports the development of robust patient-derived models that advance discovery in disease modeling, drug screening, and regenerative medicine.
Services
- iPSC Generation & Banking: Reprogramming of somatic cells into human iPSC lines, followed by expansion, validation, and long-term cryopreservation of established iPSC lines.
- Characterization & Quality Control: Assessment of pluripotency, genomic stability, and differentiation potential of iPSC lines.
- Differentiation Platforms: Generation of iPSC-derived key cell types including hematopoietic stem/progenitor cells (HSPCs), neurons, cardiomyocytes, hepatocytes, and immune cells.
- Disease Modeling & Genome Editing: Development of patient-derived and CRISPR/Cas9- genome engineered iPSC models for functional studies.
- Consultation & Experimental Support: Training and technical support in human iPSC culture, characterization, and differentiation workflows. Guidance on study design and translational applications.