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Betsy Herold, M.D.

Betsy Herold, M.D.

Professor and Harold and Muriel Block Chair in Pediatrics, Einstein

Professor, Microbiology & Immunology, Einstein

Professor, Obstetrics & Gynecology and Women, Einstein

Chief, Division of Pediatric Infectious Diseases, The Children’s Hospital at Montefiore and Einstein

Infectious diseasesHIV/AIDSMicrobicides

Human papillomavirus (HPV)Sexually transmitted infections (STI)

Dr. Herold is developing safe and effective topical microbicides for preventing HIV, genital herpes and other sexually transmitted infections.  She is currently conducting NIH-funded studies to develop microbicide-releasing vaginal rings to prevent HIV transmission. read more...

 

William R. Jacobs Jr., Ph.D.

William R. Jacobs Jr., Ph.D.

Professor, Microbiology & Immunology, Einstein

Professor, Genetics, Einstein

Leo and Julia Forchheimer Chair in Microbiology & Immunology, Einstein

Investigator, Howard Hughes Medical Institute (HHMI)

Infectious diseasesTuberculosis (TB)Vaccines

Molecular genetics

Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium  tuberculosis (MTB) - the bacteria that causes TB -  virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...

 

Liise-anne Pirofski, M.D.

Liise-anne Pirofski, M.D.

Professor, Medicine (Infectious Diseases), Einstein

Professor, Microbiology & Immunology, Einstein

Selma and Dr. Jacques Mitrani Chair in Biomedical Research, Einstein

Chief, Infectious Diseases, Department of Medicine, Einstein and Montefiore Health System

Infectious diseasesConvalescent plasmaCOVID-19PneumoniaImmunologyBacterial infections

A leading physician-scientist, Dr. Pirofski studies vaccine and antibody mediated immunity to infectious diseases, including cryptococcosis (the leading cause of fungal meningitis globally), pneumococcal pneumonia, and COVID-19. Her work has identified novel ways by which antibodies protect against pneumonia and the spread of fungal infections. She has spearheaded studies to understand the antibody response to the novel coronavirus, SARS-CoV-2.

Dr. Pirofski is co-author of the “damage-response framework of microbial pathogenesis,” a novel theory that incorporates the role of the host into the outcome of host-microbe interactions and infectious diseases.

As chief of the division of infectious diseases, Dr. Pirofski helped lead the Einstein and Montefiore response to the COVID-19 pandemic. She also co-authored a widely-cited commentary in the Journal of Clinical Investigation proposing the use of convalescent plasma as a potential treatment for COVID-19 and is leading Einstein and Montefiore’s participation in a randomized placebo-controlled clinical trial to test the efficacy of convalescent plasma in hospitalized patients.

Dr. Pirofski, who has been continuously funded by the National Institutes of Health throughout her career, is a member of the American Association of Physicians and a fellow of the American Academy of Microbiology, American College of Physicians, the Infectious Diseases Society of America, and the American Association for the Advancement of Science. She has received numerous awards for her accomplishments, including the Lifetime Achievement Award from the Albert Einstein College of Medicine Alumni Association and the American Society for Microbiology’s William A. Hinton Award, which honors outstanding contributions toward fostering the research training of underrepresented minorities in microbiology.