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Julio A. Aguirre-Ghiso, Ph.D.

Julio A. Aguirre-Ghiso, Ph.D.

Professor, Cell Biology, Medicine and Oncology

Founding director, Cancer Dormancy and Tumor Microenvironment Institute

Co-Director, Gruss-Lipper Biophotonics Center

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Tumor Microenvironment and Metastasis Program

Cancer biologyCancer dormancy and the tumor microenvironmentCancer metastasisStress signaling

Julio Aguirre-Ghiso, Ph.D., is an international leader in cancer cell dormancy and metastasis. He has helped lead a major shift in the cancer biology field by investigating how cancer cells hibernate, undetected, for long periods of time and what causes them to suddenly awaken to seed deadly, treatment-resistant metastases. read more...

 

Nir Barzilai, M.D.

Nir Barzilai, M.D.

Professor, Medicine (Endocrinology)

Director, Institute for Aging Research

Director, Nathan Shock Center of Excellence in the Basic Biology of Aging

Ingeborg and Ira Leon Rennert Chair of Aging Research

AgingBiology of agingLongevity genes

Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity. Dr. Barzilai has been profiled by major outlets, including The New York Times, PBS’ “NOVA scienceNow” and National Geographic. read more...

 

John M. Greally, Ph.D., D.Med., M.B.,B.Ch.,B.A.O.

John M. Greally, Ph.D., D.Med., M.B.,B.Ch.,B.A.O.

Director, Center for Epigenomics, Einstein

Faculty Scholar for Epigenomics, Einstein

Attending Physician, Pediatrics, The Children's Hospital at Montefiore

GeneticsEpigenetics/epigenomics

Dr. Greally began his career as a pediatrician who subspecialized in clinical genetics, seeing patients with genetic syndromes, birth defects and developmental problems. Now, Dr. Greally seeks to understand how genetic disease is caused not by DNA mutations, but due to abnormalities in how genes are switched off and on – a field known as epigenomics.  read more...

 

William R. Jacobs Jr., Ph.D.

William R. Jacobs Jr., Ph.D.

Professor, Microbiology & Immunology, Einstein

Professor, Genetics, Einstein

Leo and Julia Forchheimer Chair in Microbiology & Immunology, Einstein

Investigator, Howard Hughes Medical Institute (HHMI)

Infectious diseasesTuberculosis (TB)Vaccines

Molecular genetics

Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium  tuberculosis (MTB) - the bacteria that causes TB -  virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...

 

Robert W. Marion, M.D.

Robert W. Marion, M.D.

Professor, Pediatrics (Genetics), Einstein

Professor, Obstetrics & Gynecology and Women's Health, Einstein

Genetic diseasesAutismSudden infant death syndrome (SIDS) and CardiogeneticsIntellectual and Developmental disabilities

Dr. Marion is an internationally recognized pediatric geneticist who specializes in diagnosing and treating children with autism spectrum disorders and genetic diseases. His work with the Aguirre brothers, twins who were joined at the head and then separated, made national news in 2004. He played a key role in establishing the CardioGenetics center of Einstein and Montefiore, which provides care for families of individuals who have suffered sudden unexpected cardiac death. He is also the founder of the Williams Syndrome Center and the Dermato-Genetics Clinic at Montefiore, and treats children and adults with neurofibromatosis, intellectual disabilities, including autism spectrum disorder and spina bifida. read more...

 

Bernice E. Morrow, Ph.D.

Bernice E. Morrow, Ph.D.

Professor, Genetics

Professor, Obstetrics & Gynecology and Women's Health

Director, Translational Genetics, Department of Genetics

Sidney L. and Miriam K. Olson Professor in Cardiology

GeneticsBirth defectsChromosomal disorders

As director of translational genetics, Dr. Morrow worked with the department of pathology to expand diagnostic genetics testing at Einstein in collaboration with Montefiore Medical Center, the University Hospital for Einstein. She is now working with several clinical departments to build translational genetics research programs to discover the genetic underpinnings of complex diseases such as deafness, cleft palate and congenital heart disease. Dr. Morrow studies the molecular errors in genes that affect embryonic development and cause various birth defects read more...

 

Jan Vijg, Ph.D.

Jan Vijg, Ph.D.

Professor and Chair, Genetics

Professor, Ophthalmology and Visual Sciences

Lola and Saul Kramer Chair in Molecular Genetics

GeneticsGenomic instabilityAging

Cancer

Dr. Vijg studies the molecular genetic changes associated with aging. Instability of genome and epigenome – the entire set of an organism’s genes and the switches that control their activity –  has long been implicated as the main cause of cancer and of the loss of organ and tissue function associated with aging. read more...