Positions are immediately available for Post-Doctoral training in the McDonald Laboratory. A variety of projects exist for Post-Doctoral fellows.
Research topics include:
- Dynamics of ion channel protein translation in acquired and hereditary cardiac disorders.
- Epigenetic factors regulating K+ channel expression.
- Second-messenger regulation of ion channels.
- Assembly and trafficking of ion channels.
- Biochemical & Pharmacological characterization of novel channels from human parasites (malaria, Leishmania, toxoplasma, trypanosomes) & mycobacteria.
- Next-Generation sequencing analyses of hereditary arrhythmia syndromes.
Trainees will learn and apply a variety of techniques and approaches including cellular electrophysiology (patch-clamp), Ribosomal profiling, mRNA structure analyses, protein biochemistry, and computer modeling. Post-docs are given considerable freedom to pursue their chosen projects. Supervision and guidance is given at regular individual meetings with Dr. McDonald and regular group and Departmental "Works-in-Progress" presentations. Promising results will be presented at national meetings by the post-doc.
The Einstein campus offers a wide variety of core facilities (imaging, transgenics, structural, hybridoma, genomics, epigenomics, etc.) and hosts numerous active seminar series with world-class guest speakers. Post-doctoral fellows have access to these as well as the collegial and cooperative atmosphere among its investigators.