Clinical Disease / Epidemiology Collaboratory Leaders Nir Barzilai, M.D., Professor of Medicine and Genetics Johanna Daily, M.D., Professor of Medicine and Microbiology & Immunology Betsy Herold, M.D., Professor of Pediatrics and Microbiology & Immunology Thomas E. Rohan, M.B.B.S., Ph.D., D.H.Sc., Chair and Professor of Epidemiology & Population Health Characterization of the disease course of COVID-19 infection and mechanisms of morbidity and mortality Identification of genetic risk factors and biomarkers predictive for a more severe disease course Defining correlates of protection from reinfection by COVID-19 in patients Virologic and serologic surveillance studies of the distribution and natural history of COVID-19 in human populations