Josefa Steinhauer

Josefa Steinhauer, Ph.D.

Area of research

  • Drosophila genetics and cell biology, aging, and lipidomics

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Location

  • Yeshiva University 2495 Amsterdam Avenue Belfer Hall 1408 New York, NY 10033

Lab of Josefa Steinhauer

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Selected Publications

Banerjee SJ, Schonbrun A, Eizadshenass S, Benji S, Cantor YT, Eliach L, Lubin M, Narrowe Z, Purow J, Shulman B, Wiener L, Steinhauer J. iPLA2-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster. PLoS One. 2021;16(9):e0256738. doi: 10.1371/journal.pone.0256738. eCollection 2021. PubMed PMID: 34506510; PubMed Central PMCID: PMC8432841.
 
 
Banerjee S, Benji S, Liberow S, Steinhauer J. Using Drosophila melanogaster To Discover Human Disease Genes: An Educational Primer for Use with "Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target". Genetics. 2020 Nov;216(3):633-641. doi: 10.1534/genetics.120.303495. PubMed PMID: 33158986; PubMed Central PMCID: PMC7648582.
 
Sepil I, Hopkins BR, Dean R, Bath E, Friedman S, Swanson B, Ostridge HJ, Harper L, Buehner NA, Wolfner MF, Konietzny R, Thézénas ML, Sandham E, Charles PD, Fischer R, Steinhauer J, Kessler BM, Wigby S. Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in Drosophila. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17094-17103. doi: 10.1073/pnas.2009053117. Epub 2020 Jul 1. PubMed PMID: 32611817; PubMed Central PMCID: PMC7382285.
 
Delventhal R, Steinhauer J. A course-based undergraduate research experience examining neurodegeneration in Drosophila melanogaster teaches students to think, communicate, and perform like scientists. PLoS One. 2020;15(4):e0230912. doi: 10.1371/journal.pone.0230912. eCollection 2020. PubMed PMID: 32282825; PubMed Central PMCID: PMC7153876.
 
 
Steinhauer J, Statman B, Fagan JK, Borck J, Surabhi S, Yarikipati P, Edelman D, Jenny A. Combover interacts with the axonemal component Rsp3 and is required for Drosophila sperm individualization. Development. 2019 Sep 2;146(17). doi: 10.1242/dev.179275. PubMed PMID: 31391193; PubMed Central PMCID: PMC6765124.
 
 
Hawley S, Morris J, Pokrywka N, Smith M, Steinhauer J, Stevens T. Why is genetics education so important. Trends in genetics : TIG. 2018 January; 34(1):1-4. doi: 10.1016/j.tig.2017.10.006.
 
 
Kondo S, Vedanayagam J, Mohammed J, Eizadshenass S, Kan L, Pang N, Aradhya R, Siepel A, Steinhauer J, Lai EC. New genes often acquire male-specific functions but rarely become essential in Drosophila. Genes Dev. 2017 Sep 15;31(18):1841-1846. doi: 10.1101/gad.303131.117. PubMed PMID: 29051389; PubMed Central PMCID: PMC5695085.
 
 
Steinhauer J. Co-culture Activation of MAP Kinase in Drosophila S2 Cells. Methods Mol Biol. 2017;1487:235-241. doi: 10.1007/978-1-4939-6424-6_17. PubMed PMID: 27924571; PubMed Central PMCID: PMC5588906.
 
 
Steinhauer J. Separating from the pack: Molecular mechanisms of Drosophila spermatid individualization. Spermatogenesis. 2015 May-Aug;5(2):e1041345. doi: 10.1080/21565562.2015.1041345. eCollection 2015 May-Aug. PubMed PMID: 26413413; PubMed Central PMCID: PMC4581072.
 
 
Ben-David G, Miller E, Steinhauer J. Drosophila spermatid individualization is sensitive to temperature and fatty acid metabolism. Spermatogenesis. 2015 Jan-Apr;5(1):e1006089. doi: 10.1080/21565562.2015.1006089. eCollection 2015 Jan-Apr. PubMed PMID: 26413411; PubMed Central PMCID: PMC4581069.
 
 
Steinhauer J, Liu HH, Miller E, Treisman JE. Trafficking of the EGFR ligand Spitz regulates its signaling activity in polarized tissues. J Cell Sci. 2013 Oct 1;126(Pt 19):4469-78. doi: 10.1242/jcs.131169. Epub 2013 Jul 31. PubMed PMID: 23902690; PubMed Central PMCID: PMC3784823.
 
 
Legent K, Steinhauer J, Richard M, Treisman JE. A screen for X-linked mutations affecting Drosophila photoreceptor differentiation identifies Casein kinase 1α as an essential negative regulator of wingless signaling. Genetics. 2012 Feb;190(2):601-16. doi: 10.1534/genetics.111.133827. Epub 2011 Nov 17. PubMed PMID: 22095083; PubMed Central PMCID: PMC3276650.
 
Steinhauer J, Gijón MA, Riekhof WR, Voelker DR, Murphy RC, Treisman JE. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec;20(24):5224-35. doi: 10.1091/mbc.e09-05-0382. PubMed PMID: 19864461; PubMed Central PMCID: PMC2793297.
 
Steinhauer J, Treisman JE. Lipid-modified morphogens: functions of fats. Curr Opin Genet Dev. 2009 Aug;19(4):308-14. doi: 10.1016/j.gde.2009.04.006. Epub 2009 May 11. Review. PubMed PMID: 19442512; PubMed Central PMCID: PMC2731821.
 
 
Steinhauer J, Kalderon D. Microtubule polarity and axis formation in the Drosophila oocyte. Dev Dyn. 2006 Jun;235(6):1455-68. doi: 10.1002/dvdy.20770. Review. PubMed PMID: 16586443.
 
Steinhauer J, Kalderon D. The RNA-binding protein Squid is required for the establishment of anteroposterior polarity in the Drosophila oocyte. Development. 2005 Dec;132(24):5515-25. doi: 10.1242/dev.02159. Epub 2005 Nov 16. PubMed PMID: 16291786.
 
Steinhauer J, Agha R, Pham T, Varga AW, Goldberg MB. The unipolar Shigella surface protein IcsA is targeted directly to the bacterial old pole: IcsP cleavage of IcsA occurs over the entire bacterial surface. Mol Microbiol. 1999 Apr;32(2):367-77. doi: 10.1046/j.1365-2958.1999.01356.x. PubMed PMID: 10231492.