Shilpa Vasishta
Jared E. Coe
Daniel A. Burack
Barry S. Zingman
<p>Barry S. Zingman, M.D., has been the Medical Director of the AIDS Center at Montefiore since 2003 following his service as Medical Director of the AIDS Center's Center for Positive Living/Infectious Diseases (CPL/ID) Clinic for five years.</p>
<p>Dr. Zingman directs the largest multidisciplinary and multispecialty adult HIV/AIDS treatment and prevention program in New York State. His program’s clinical sites include (1) the Center for Positive Living/I.D. Clinic, for HIV, Hepatitis C, and general Infectious Diseases care; (2) The Oval Center at Montefiore, which provides screening and treatment for sexually transmitted infections, HIV pre- and post-exposure prophylaxis programs, and Hepatitis C care; and (3) other inpatient and outpatient sites at the Moses Division of Montefiore Medical Center. He has been Principal Investigator or Medical Director on over 75 HIV/AIDS-related research protocols and grants. These currently include grants from HRSA, the New York State Department of Health's AIDS Institute, NIH, and industry for multidisciplinary HIV primary care and testing; HIV retention, adherence and viral suppression; studies of broadly-neutralizing therapeutic HIV antibodies; new HIV viral load assays; response to pneumococcal vaccine in HIV+ and HIV- individuals; and studies of other new antiretroviral agents.</p>
<p>Dr. Zingman directs an HIV research team consisting of 6 study coordinators that enrolls over 200 patients per year into research protocols.</p>
<p>Dr. Zingman is Professor of Clinical Medicine at Albert Einstein College of Medicine. He is formerly Chair of the AIDS Institute's Medical Care Criteria Committee (the principal body setting HIV care guidelines in NYS); former Vice-Chair of the NYS AIDS Institute's Quality of Care Advisory Committee; and Chair or Member on numerous other state and national HIV quality and standard of care subcommittees. He is a practicing infectious diseases subspecialist and maintains an active patient panel in the CPL/ID Clinic and the Department of Medicine Faculty Practice.</p>
<p> Dr. Zingman directs the largest multidisciplinary and multispecialty adult HIV/AIDS treatment and prevention program in New York State. His program’s clinical sites include (1) the Center for Positive Living/I.D. Clinic, for HIV, Hepatitis C, and general Infectious Diseases care; (2) The Oval Center at Montefiore, which provides screening and treatment for sexually transmitted infections, HIV pre- and post-exposure prophylaxis programs and Hepatitis C care; and (3) other inpatient and outpatient sites at the Moses Division of Montefiore Medical Center. He has been Principal Investigator or Medical Director on over 75 HIV/AIDS-related research protocols and grants. These currently include grants from HRSA, the New York State Department of Health's AIDS Institute, NIH, and industry for multidisciplinary HIV primary care and testing; HIV retention, adherence and viral suppression; studies of broadly-neutralizing therapeutic HIV antibodies; new HIV viral load assays; response to pneumococcal vaccine in HIV+ and HIV- individuals; and studies of other new antiretroviral agents.</p>
<p>Barry S. Zingman, MD, is Medical Director, AIDS Center and Clinical Director, Infectious Diseases at Montefiore Einstein, and Professor, Medicine at our Albert Einstein College of Medicine. Dr. Zingman cares for people with a wide range of infectious disease conditions including HIV care, HIV prevention (PrEP; PEP), sexually transmitted infections, COVID, MPOX (monkeypox), other viral infections, diabetic foot infections, bone infections, heart and lung infections, post-surgical infections, tuberculosis and many others.</p><p>After completing his Bachelor of Arts in biochemistry at Brandeis University in 1981, Dr. Zingman attended New York University School of Medicine, earning his Doctor of Medicine in 1985. He completed his internship and residency in internal medicine at Boston City Hospital in 1988. Dr. Zingman continued his training at Boston University School of Medicine, completing clinical and research fellowships in infectious diseases in 1991.</p><p>Dr. Zingman’s research focuses on new treatments, vaccines, and other preventive strategies for infectious diseases including HIV, sexually transmitted infections, other viral infections, E coli urinary tract infections and others. He has shared his work through peer-reviewed journals, articles, case reports, book chapters, abstracts, and other media as well as presentations, invited lectures and webinars.</p><p>Dr. Zingman is board certified in Infectious Diseases and Internal Medicine. He is a member of the Infectious Disease Society of America (IDSA) and the HIV Medicine Association of IDSA. In 2017, he was inducted into the Leo M. Davidoff Society for distinguished, caring and committed teaching of medical students.</p>
Louis M. Weiss
<p><em><span style="text-decoration: underline;">Toxoplasma gondii</span></em>, microsporidiosis, stage differentiation, polar tube structure and function</p>
<p><strong>Toxoplasmosis:</strong> <em>Toxoplasma gondii</em> is a ubiquitous Apicomplexan protozoan parasite that infects humans, mammals and birds. Despite recent progress in understanding the biology of the rapidly replicating form (tachyzoite), very little is known about the cyst form (bradyzoite). The bradyzoite stage plays a critical role in maintenance of latent infection, the relapse of infections and the development of chronic neurologcial disease. Our research is focused on the identification of cyst wall (bradyzoite) proteins and how they function. </p>
<p><strong>Microsporidiosis:</strong> The phylum Microspora consists of organisms collectively known as microsporidia, that are "emerging" human and veterinary pathogens. A microsporidian-specific organelle, the polar tube, is involved in invasion. While the description of the polar tube as a unique microsporidian structure occurred over 100 years ago, the biochemical components of this structure and the mechanism of its formation during invasion remain to be definitively determined. The laboratory is focused on projects invovling the: (1) characterization of the structure and composition of the polar tube and spore wall, and (2) the identificiation of therapeutic targets for the treatment of microsporidiosis. </p>
Treatment and diagnosis of infectious diseases, with a focus on parasitology and global health.
Investigates the biology of Toxoplasma gondii and its ability to cause latent infections, with a focus on the composition and structure of the T. gondii tissue cyst.
<p>Mayoral J, Guevara RB, Rivera-Cuevas Y, Tu V, Tomita T, Romano JD, Gunther-Cummins L, Sidoli S, Coppens I, Carruthers VB, Weiss LM. Dense Granule Protein GRA64 interacts with host cell ESCRT proteins during <em>Toxoplasma gondii</em> infection.mBio. 2022 Jun 22:e0144222. doi: 10.1128/mbio.01442-22.</p>
<p>Tomita T, Mukhopadhyay D, Han B, Yakubu R, Tu V, Mayoral J, Sugi T, Ma Y, Saeij JPJ, Weiss LM. <em>Toxoplasma gondii</em> matrix antigen 1 is a secreted immunomodulatory effector. mBio. 2021 May 18;12(3):e00603-21. </p>
<p>Flores J, Takvorian PM, Weiss LM, Cali A, Gao N. Human microsporidian pathogen <em>Encephalitozoon intestinalis</em> impinges on enterocyte membrane trafficking and signaling. J Cell Sci. 2021 Feb 15:jcs.253757. doi: 10.1242/jcs.253757.</p>
<p>Mayoral J, Tomita T, Tu V, Aguilan JT, Sidoli S, Weiss LM. <em>Toxoplasma gondii</em> PPM3C, a secreted protein phosphatase, affects parasitophorous vacuole effector export. PLoS Pathog. 2020 Dec 28;16(12):e1008771. doi: 10.1371/journal.ppat.1008771. </p>
<p>Mayoral J, Shamamian P Jr, Weiss LM. In Vitro Characterization of protein effector export in the bradyzoite stage of Toxoplasma gondii. mBio. 2020 Mar 10;11(2). pii: e00046-20. doi: 10.1128/mBio.00046-20. PMID: 32156805</p>
<p><span lang="EN">Tu V, Tomita T, Sugi T, Mayoral J, Han B, Yakubu RR, Williams T, Horta A, Ma Y, Weiss LM. The <em>Toxoplasma gondii</em> cyst wall interactome. mBio. 2020 Feb 4;11(1). pii: e02699-19. doi: 10.1128/mBio.02699-19.PMID: 32019789</span></p>
<p>Tu V, Mayoral J, Yakubu RR, Tomita T, Sugi T, Han B, Williams T, Ma Y, Weiss LM.MAG2, a <em>Toxoplasma gondii</em> bradyzoite stage-specific cyst matrix protein. mSphere. 2020 Feb 19;5(1). pii: e00100-20. doi:10.1128/mSphere.00100-20.PMID: 32075884</p>
<p><span lang="EN">Han B, Ma Y, Tu V, Tomita T, Mayoral J, Williams T, Horta A, Huang H, Weiss LM Microsporidia interact with host cell mitochondria via voltage-dependent anion channels using sporoplasm Surface Protein 1. mBio. 2019 Aug 20;10(4). pii: e01944-19. doi: 10.1128/mBio.01944-19. PMID: 31431557</span> <span lang="EN">PMC6703431</span></p>
<p><span lang="EN">Takvorian PM, Han B, Cali A, Rice WJ, Gunther L, Macaluso F, Weiss LM. An ultrastructural study of the extruded polar tube of<em> Anncaliia algerae</em> (Microsporidia). J Eukaryot Microbiol. 2019 Jul 22. doi: 10.1111/jeu.12751. PMID: 31332877</span></p>
<p><span lang="EN">Tomita T, Wang H, Wu P, Weiss LM.Stage-specific and selective delivery of caged azidosugars into the intracellular parasite <em>Toxoplasma gondii</em> by using an esterase-ester pair technique. mSphere. 2019 May 29;4(3). pii: e00142-19. doi: 10.1128/mSphere.00142-19. PMID: 31142619</span></p>
<p>Tu V, Mayoral J, Sugi T, Tomita T, Han B, Ma YF, Weiss LM. Enrichment and proteomic characterization of the cyst wall from in vitro <em>Toxoplasma gondii</em> cysts. mBio. 2019 Apr 30;10(2). pii: e00469-19. doi: 10.1128/mBio.00469-19. PMID: 31040239</p>
<p>Sugi T, Tu V, Ma Y, Tomita T, Weiss LM. <em>Toxoplasma gondii</em> requires glycogen phosphorylase for balancing amylopectin storage and for efficient production of brain cysts. mBio. 2017 Aug 29;8(4). pii: e01289-17. doi: 10.1128/mBio.01289-17.PMID: 28851850 PMC5574715</p>
<p>Yakubu RR, Silmon de Monerri NC, Nieves E, Kim K, Weiss LM. Comparative Monomethylarginine proteomics suggests that protein arginine methyltransferase 1 (PRMT1) is a significant contributor to arginine monomethylation in <em>Toxoplasma gondii</em>. Mol Cell Proteomics. 2017 Apr;16(4):567-580. doi: 10.1074/mcp.M117.066951. Epub 2017 Jan 31.PMID: 28143887</p>
<p>Han B, Polonais V, Sugi T, Yakubu R, Takvorian PM, Cali A, Maier K, Long M, Levy M, Tanowitz HB, Pan G, Delbac F, Zhou Z, Weiss LM. The role of microsporidian polar tube protein 4 (PTP4) in host cell infection. PLoS Pathog. 2017 Apr 20;13(4):e1006341. doi: 10.1371/journal.ppat.1006341. eCollection 2017 Apr. PMID: 28426751</p>
<p>Sugi T, Ma YF, Tomita T, Murakoshi F, Eaton MS, Yakubu R, Han B, Tu V, Kato K, Kawazu S, Gupta N, Suvorova ES, White MW, Kim K, Weiss LM. Toxoplasma gondii cyclic AMP-dependent protein kinase subunit 3 is involved in the switch from tachyzoite to bradyzoite development. mBio. 2016 May 31;7(3). pii: e00755-16. doi: 10.1128/mBio.00755-16. PMID: 27247232 PMCID: PMC4895117</p>
<p>El Bissati K, Suvorova ES, Xiao H, Lucas O, Upadhya R, Yan Fen Ma YF, Hogue Angeletti R, White MW, Weiss LM, Kim K <em>Toxoplasma gondii</em> arginine methyltransferase 1 (PRMT1) regulates centrosome dynamics during tachyzoite cell division. mBio. 2016 Feb 2;7(1):e02094-15. doi: 10.1128/mBio.02094-15. PMID: 26838719 PMCID: PMC4742710</p>
<p>Silmon de Monerri NC, Yakubu RR, Chen AL, Bradley PJ, Nieves E, Weiss LM, Kim K. The Ubiquitin proteome of <em>Toxoplasma gondi</em>i reveals roles for protein ubiquitination in cell-cycle transitions. Cell Host Microbe. 2015 Nov 11;18(5):621-33. doi: 10.1016/j.chom.2015.10.014. PMID: 26567513</p>
<p>Tomita T, Bzik DJ, Ma YF, Fox BA, Markillie LM, Taylor RC, Kim K, Weiss LM.The <em>Toxoplasma gondii</em> cyst wall protein CST1 is critical for cyst wall integrity and promotes bradyzoite persistence. PLoS Pathog. 2013 Dec;9(12):e1003823. doi: 10.1371/journal.ppat.1003823. PMID:24385904</p>
<p>Morada M, Lee S, Gunther-Cummins L, Weiss LM, Widmer G, Tzipori S, Yarlett N. Continuous culture of <em>Cryptosporidium parvum</em> using hollow fiber technology. Int J Parasitol. 2015 Sep 2. pii: S0020-7519(15)00220-9. doi: 10.1016/j.ijpara.2015.07.006. PMID: 26341006</p>
<p>Ma Y, Weiss LM, Huang H. Inducible suicide vector systems for <em>Trypanosoma cruzi</em>. Microbes Infect. 2015 Jun;17(6):440-50. doi: 10.1016/j.micinf.2015.04.003. Epub 2015 Apr 18. PMID: 25899945</p>
<p>Nardelli SC, Che FY, Silmon de Monerri NC, Xiao H, Nieves E, Madrid-Aliste C, Angel SO, Sullivan WJ Jr, Angeletti RH, Kim K, Weiss LM. The Histone Code of <em>Toxoplasma gondii</em> Comprises Conserved and Unique Posttranslational Modifications. mBio. 2013 Dec 10;4(6). doi:pii: e00922-13. 10.1128/mBio.00922-13. PMID:24327343</p>
<p>Pombert JF,Selman M,Burki F,Bardell FT,Farinelli L,Solter LF,Whitman DW,Weiss LM, Corradi N, Keeling PJ. Gain and loss of multiple functionally related, horizontally transferred genes in the reduced genomes of two microsporidian parasites. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12638-43. Epub 2012 Jul 16. PMID:22802648</p>
<p>Ghosh K, Nieves E, Keeling P, CaliA, Weiss LM. A new vesicular compartment in <em>Encephalitozoon cuniculi</em>. Microbes Infect. 2012 Apr;14(4):324-8. PMID:22166342</p>
<p>Ghosh K, Nieves E, Keeling P, Pombert JF, CaliA, Weiss LM. A branching network of proteinaceous filaments within the parasitophorous vacuole of<em> Encephalitozoon cuniculi</em> and <em>Encephalitozoon hellem</em>. Infect Immun. 2011 Jan 10. PMID: 21220485</p>
<p>Bouzahzah B, Nagajyothi F, Ghosh K, Takvorian PM, CaliA, Tanowitz HB, Weiss LM. Interactions of <em>Encephalitozoon cuniculi</em> polar tube proteins. Infect Immun. 2010 Jun;78(6):2745-53. Epub 2010 Mar 22. PMID: 20308291</p>
<p>Alvarado JJ, Nemkal A, Sauder JM, Russell M, Akiyoshi DE, Shi W, Almo SC, Weiss LM. Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470. Mol Biochem Parasitol. 2009 Aug 4. PMID: 19660503</p>
<p><strong>BOOKS</strong></p>
<p>Weiss LM and Kim K (eds.) <em>Toxoplasma gondii</em> the model Apicomplexan: Methods and Applications, Elsevier Press (Academic Press), 3rd edition, 2020.</p>
<p>Weiss LM and Reinke AW (eds.) Microsporidia: Current Advances in Biology, Springer, 2022.</p>
<p>Weiss LM and Becnel JJ (eds.) Microsporidia: Pathogens of Opportunity, Wiley-Blackwell, 2014.</p>
<p>Louis M. Weiss, MD, MPH, is Vice Chair, Academic Affairs and Research, Pathology, Co-Director, Einstein Global Health Center and Professor, Pathology and Medicine (Infectious Diseases) at Montefiore Einstein. His clinical expertise is in the treatment and diagnosis of infectious diseases, with a focus on parasitology and global health.</p><p>After obtaining his Bachelor of Arts in biology and chemistry from Lehigh University in 1978, Dr. Weiss earned his Doctor of Medicine and Master of Public Health at Johns Hopkins University in 1982. Following this, Dr. Weiss completed his internship and residency in medicine at the University of Chicago in 1985 and an infectious diseases fellowship at Einstein Montefiore in 1989.</p><p>Dr. Weiss investigates the biology of <em>Toxoplasma gondii</em> and its ability to cause latent infections, with a focus on the composition and structure of the <em>T. gondii</em> tissue cyst. He also investigates the biology of infection due to the microsporidia, with a focus on the composition of the polar tube and how it functions during microsporidian invasion of a host cell. His research has been published in numerous peer-reviewed journals, articles, books and chapters, and he has presented this research both nationally and internationally. Dr. Weiss has been a reviewer for scientific journals including <em>mBIO</em>, the <em>Journal of Eukaryotic Microbiology</em>, the <em>American Journal of Tropical Medicine and Hygiene, PLOS Pathogens</em>, the <em>Journal of Infectious Diseases</em> and <em>Experimental Parasitology</em>, and is an editor for <em>mBIO</em> and <em>Microbes and Infection</em>.</p><p>Dr. Weiss is board certified in Internal Medicine and Infectious Diseases. He is a Fellow of the Infectious Diseases Society of America, the American College of Physicians and the American Academy of Microbiology of the American Society of Microbiology. In 2000, Dr. Weiss was inducted into the Leo M. Davidoff Society for his outstanding teaching of medical students.</p>
Anjali Sharma
<p>My research focuses on metabolic complications of HIV infection associated with aging, particularly among women. My current NIH K23 funded research investigates underlying mechanisms of bone loss and the relationship between disorders of bone and fat metabolism in HIV infection, in an effort to explain the high prevalence of premature bone disease in HIV-infected women in the Women's Interagency HIV Study (WIHS), the largest and longest-running cohort study of HIV infection in women in the United States. I joined the Einstein faculty in 2013 to build on existing collaborations with expert HIV researchers, and more importantly, to develop new collaborations with scientific experts investigating aging, and conditions associated with aging that are prevalent in HIV-infected populations. I recently found that HIV-infected women had greater fracture incidence than uninfected women in WIHS, prompting an investigation into the prevalence and risks for falls in the WIHS. We found that 18% of HIV+ women reported at least one fall within 6 months, and that factors affecting cognition (such as subjective cognitive complaints and CNS active medications) were associated with greater falls risk. Among HIV-infected women age 50 or older, 1/3 reported having a fall annually, similar to the falls incidence in persons age >65 years in the general U.S. population. Additionally, I am conducting research on visceral adiposity and age-related metabolic disorders among HIV-infected women, in a project that utilizes two novel imaging techniques to quantify visceral adiposity and skeletal microarchitecture in aging HIV-infected and uninfected women, to assess the relationships between visceral adiposity and metabolic disorders associated with aging (osteoporosis, sarcopenia, and subclinical atherosclerosis) in HIV-infected women. Prior to joining Einstein faculty, I was awarded a grant to study factors associated with bone loss among women and men with and at-risk for HIV infection, from the Robert Wood Johnson Foundation Physician Faculty Scholars Program, as well as an AIDS-Science Track Award for Research Transition (R03) by the National Institute on Drug Abuse, to study the role of insulin-like growth factor in the development of reduced bone mineral density in two large cohorts of drug using men and women with and at-risk for HIV infection. Additional areas of research interest includethe effects of regional adiposity and obesity on health in HIV-infected populations.</p>
<ol>
<li><strong>Sharma A, </strong>Tian F, Yin MT, Keller MJ, Cohen M, Tien PC. Association of Regional Body Composition with Bone Mineral Density in HIV-infected and Uninfected Women: Women's Interagency HIV Study. J Acquir Immune Defic Syndr. 2012 Dec 1; 61(4):469-76. PMCID: PMC3494812.</li>
<li>Shlipak MG, Scherzer R, Abraham A, Tien PC, Grunfeld C, Peralta CA, Devarajan P, Bennett M, Butch AW, Anastos K, Cohen MH, Nowicki M, <strong>Sharma A</strong>, Young MA, Sarnak MJ, Parikh CR. Urinary Markers of Kidney Injury and Kidney Function Decline in HIV-Infected Women: Biomarkers and Kidney Decline. J Acquir Immune Defic Syndr. 2012 Dec 15; 61(5):565-73. PMC3509242.</li>
<li>Laisaar KT, Uusküla A, <strong>Sharma A</strong>, DeHovitz JA, Amico KR. Developing an adherence support intervention for patients on antiretroviral therapy in the context of the recent IDU-driven HIV/AIDS epidemic in Estonia. AIDS Care. 2013;25(7):863-73. PMCID: PMC3651786. </li>
<li>Aziz M, Adeyemi OM, Livak B, Burke-Miller J, French A, Glesby MJ,<strong> Sharma A</strong>, Young M, Villacres M, Tien P, Golub E, Cohen M. Vitamin D insufficiency may impair CD4 recovery among HIV infected women with advanced disease on HAART. AIDS. 2013 Feb 20;27(4):573-8. PMCID: PMC3902982.</li>
<li>Oboho I, Abraham A, Benning L, Anastos K, <strong>Sharma A</strong>, Young M, Burian P, Gandhi M, CohenM, Szczech L. Tenofovir use and urinary biomarkers among HIV-infected women in the Women's Interagency HIV Study (WIHS). J Acquir Immune Defic Syndr. 2013 Apr 1;62(4):388-95. PMCID: PMC3692572.</li>
<li>Adeyemi OM, Livak B, Orsi J, Glesby MJ, Villacres MC, Weber KM, <strong>Sharma</strong><strong>A</strong>, Golub E, Young M, Cohen M, Tien PC. Vitamin D and Insulin Resistance in Non-Diabetic Women’s Interagency HIV Study Participants. AIDS Patient Care STDS. 2013 Jun;27(6):320-5. PMCID: PMC3671624.</li>
<li>Hoy J, Grund B, Roediger M, Ensrud KE, Brar I, Colebunders R, De Castro N, Johnson M, <strong>Sharma</strong><strong>A</strong>, Carr A, for the INSIGHT SMART Body Composition Substudy Group. Interruption or deferral of antiretroviral therapy reduces markers of bone turnover compared with continuous therapy: the SMART Body Composition Substudy. J Bone Miner Res. 2013 June; 28(6):1264–1274. PMCID: PMC3657331.</li>
<li>Driver TH, Scherzer R, Peralta CA, Tien PC, Estrella MM, Parikh CR, Butch AW, Anastos K, Cohen MH, Nowicki M, <strong>Sharma A</strong>, Young MA, Abraham A, Shlipak MG. Comparisons of creatinine and cystatin C for detection of kidney disease and prediction of all-cause mortality in HIV‐infected women. <em>AIDS. </em>2013 Sep 10;27(14):2291-9. PMCID: PMC3919542.</li>
<li>Schwartz JB, Moore KL, Yin M, <strong>Sharma</strong><strong>A</strong>, Merenstein D, Islam T, Golub ET, Tien PC, Adeyemi OM. Relationship of vitamin D, HIV, HIV treatment and lipid levels in the Women’s Interagency HIV study of HIV-infected and uninfected women in the United States. Journal of the International Association of Physicians in AIDS Care (JIAPAC) 2014 May-Jun;13(3):250-9. PMCID: PMC4016117..</li>
<li>Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Devarajan P, Anastos K, Cohen MH, Nowicki M, <strong>Sharma A</strong>, Young M, Tien PC, Grunfeld C, Parikh CR, Shlipak MG. Does HIV infection promote early kidney injury in women? Antivir Ther. 2014;19(1):79-87. PMCID: PMC3933452.</li>
<li>Peralta C, Scherzer R, Grunfeld C, Abraham A, Tien P, Devarajan P, Bennett M, Butch A, Anastos K, Cohen M, Nowicki M, <strong>Sharma A</strong>, Young M, Sarnak M, Parikh C, Shlipak M. Urinary biomarkers of kidney injury are associated with all-cause mortality in the Women's Interagency HIV Study (WIHS). HIV Med. 2014 May;15(5):291-300. PMCID: PMC3975680.</li>
<li>Mirmirani P, Maurer T, Cohen M, D’Souza G, Karim R, Plankey M, Robison E, <strong>Sharma</strong><strong>A</strong>, Tien PC, Hessol NA. Investigating the Effects of Metabolic Dysregulation on Hair Follicles: A Comparison of HIV-Infected Women with and Without Central Lipohypertrophy. Int J Dermatolol. 2014 Oct;53(10):e443-8. PMCID: PMC3785560.</li>
<li><strong>Sharma A</strong>, Bynum SA, Schneider MF, Cox C, Tien PC, Hershow RC, Gustafson D, Plankey MW. Changes in Body Mass Index Following HAART initiation among HIV-infected Women in the Women’s Interagency HIV Study. J AIDS Clin Res. 2014. 5:323. PMCID: PMC4285631</li>
<li>Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Cohen MH, Nowicki M, <strong>Sharma A</strong>, Young M, Tien PC, Ix JH, Sarnak MJ, Parikh CR, Shlipak MG. Association of Urine α1-Microglobulin with Kidney Function Decline and Mortality in HIV-Infected Women. Clin J Am Soc Nephrol. 2015 Jan 7;10(1):63-73. PMCID: PMC4284407</li>
<li>Lang J, Scherzer R, Tien PC, Parikh CR, Anastos K, Estrella MM, Abraham AG, <strong>Sharma A</strong>, Cohen MH, Butch AW, Nowicki M, Grunfeld C, Shlipak MG. Serum albumin and kidney function decline in HIV-infected women. Am J Kidney Dis. 2014 Oct;64(4):584-91. PMCID: PMC4177337</li>
<li>Jotwani V, Shlipak MG, Scherzer R, Parekh RS, Kao WH, Bennett M, Cohen MH, Nowicki M, <strong>Sharma A</strong>, Young M, Tien PC, Parikh CR, Estrella MM. APOL1 Genotype and Glomerular and Tubular Kidney Injury in Women With HIV. Am J Kidney Dis. 2015 Jun;65(6):889-98. doi: 10.1053/j.ajkd.2015.02.329. Epub 2015 Apr 24. PubMed PMID: 25921719.</li>
<li><strong>Sharma A, </strong>Flom PL, Rosen CJ, Schoenbaum EE<strong>. </strong>Racial Differences in Bone Loss and Relation to Menopause Among HIV-infected and Uninfected Women. Bone. 2015 Apr 18;77:24-30. doi: 10.1016/j.bone.2015.04.018. [Epub ahead of print] PMCID: PMC4418198.</li>
<li><strong>Sharma A</strong>, Shi Q, Hoover DR, Anastos K, Tien PC, Young MA, Cohen MH, Golub ET, Gustafson D, Yin MT. Increased fracture incidence in middle-aged HIV-infected and uninfected women: updated results from the Women’s Interagency HIV Study. J Acquir Immune Defic Syndr. 2015 Sep 1; 70(1):54-61. PMID: 26322667 [PubMed - in process] PMCID: PMC4557627</li>
<li>Baxi SM, Scherzer R, Greenblatt RM, Minkoff H, <strong>Sharma A</strong>, Cohen M, Young MA, Abraham AG, and Shlipak MG. Higher Tenofovir Exposure is Associated with Longitudinal Declines in Kidney Function in Women Living with HIV. AIDS. 2016 Feb 20;30(4):609-18</li>
<li><strong>SharmaA</strong>, HooverDR, ShiQ, Gustafson D, Plankey MW, HershowRC, TienPC, GolubET, AnastosA. Relationship between Body Mass Index and Mortality in HIV-infected HAART Users in the Women's Interagency HIV Study. PLoS One. 2015 Dec 23;10(12):e0143740. doi: 10.1371/journal.pone.0143740. eCollection 2015.</li>
<li>Scherzer R, Lin H, Abraham A, Thiessen-Philbrook H, Parikh CR, Bennett M, Cohen MH, Nowicki M, Gustafson DR<strong>, Sharma A,</strong> Young M, Tien P, Jotwani V, and Shlipak MG. Use of urine biomarker-derived clusters to predict risk of CKD and all-cause mortality in HIV-infected women. Nephrol Dial Transplant. 2016 Jan 10. </li>
</ol>
Heather B. Root
Paul F. Riska
<p>My research interests are: Clostridium difficile, Tuberculosis, Molecular epidemiology, Molecular mechanisms of antibiotic resistance, Bacteriophage Therapy. </p>
Yoram A. Puius
<p>Dr. Yoram Puius completed MD and PhD degrees at the Albert Einstein College of Medicine in 2001. His original research was in the structural biology of signal transduction proteins in the laboratory of Dr. Steven Almo. After completing a residency in Internal Medicine at New York Hospital, he completed a fellowship in Infectious Diseases at Columbia Presbyterian, followed by an additional year at Tufts Medical Center focusing on infections in transplant recipients.</p>
<p>Dr. Puius's first position was at Roger Williams Medical Center in Providence, Rhode Island in 2007. There he served as Medical Director of Infection Control and Assistant Program Director of the Internal Medicine Residency, while holding the rank of Assistant Professor at Boston University School of Medicine. In Rhode Island he further developed interest and expertise in tickborne diseases. In addition, he directed infectious diseases protocols and education for the sole Bone Marrow Transplant Unit in the state of Rhode Island. </p>
<p>Since joining Einstein-Montefiore in 2011, Dr. Puius has worked closely with transplant teams providing inpatient and outpatient consultations, working on protocols for various selection committees, and developing an online transplant infections curriculum. He was promoted to the rank of Associate Professor in 2018. He has also served as Associate Program Director for the Fellowship in Infectious Diseases. He remains clinically active in the evaluation and treatment of tickborne diseases.</p>
<p>Dr. Puius is a member of the Infectious Diseases Society of America, the American Society for Transplantation, the Transplantation Society, and the International Society for Heart and Lung Transplantation. He is on the editorial boards of <em>Clinical Transplantation</em> and <em>Transplant Infectious Diseases</em>, and a reviewer for several other journals.</p>
<p>He publishes and speaks regionally on infections in the immunocompromised host and Lyme disease. He also chairs the working group to maintain the online Transplant Infectious Diseases library for the American Society of Transplantation (AST) ID Community of Practice, at http://transplantid.net/. In addition, he initatied a working group for AST to create standardized patient materials for safe living after transplantation. In 2024 he was selected as a Fellow of the American Society of Transplantation.</p>
<p>Clinical Interests:</p>
<p>- Infections in the immunocompromised host, including recipients of kidney, liver, heart, and stem cell transplants</p>
<p>- Infections in patients with hematological malignancies</p>
<p>- Infections in patients with Left Ventricular Assist Devices</p>
<p>- Lyme disease</p>
<p>- Pre-travel counseling and vaccination for the immunocompromised patient</p>
<p>- Online educational resources in transplant infectious diseases</p>
<p> </p>
Left ventricular assist device infections
Treating infections in the immunocompromised host, including recipients of solid organ transplants, patients with hematologic malignancies and recipients of cellular therapy.
Infections in left ventricular assist device recipients, heart transplant recipients and kidney transplant recipients.
<p class="MsoNormal" style="margin-left: .25in; text-indent: -.25in; mso-list: l0 level1 lfo1;"><!-- [if !supportLists]--><span style="font-size: 10pt;"><span style="mso-list: Ignore;">1.<span style="font-style: normal; font-variant: normal; font-kerning: auto; font-optical-sizing: auto; font-feature-settings: normal; font-variation-settings: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Levin, S., Mayer, D., <strong>Puius, Y.A.</strong>, Arora, S., and Gileles-Hillel A. (2024) Things We Do for No Reason™: Routine respiratory pathogen panels for emergency department and hospitalized patients.<span style="mso-spacerun: yes;"> </span><em>J. Hosp. Med.</em> </span><a href="https://doi.org/10.1002/jhm.13365"><span style="font-size: 10.0pt;">https://doi.org/10.1002/jhm.13365</span></a></p>
<p class="MsoNormal" style="margin-left: .25in;"><span style="font-size: 10pt;"> </span></p>
<p class="MsoNormal" style="margin-left: .25in; text-indent: -.25in; mso-list: l0 level1 lfo1;"><span style="font-size: 10pt;"><span style="mso-list: Ignore;">2. </span></span><span style="font-size: 10.0pt;">Mullis, C.E., Heldman, M., Bahr, N.C., Minamoto, G.Y., <strong>Puius. Y.A.</strong>, and Malinis, M. (2024) Persistent fever after coronavirus disease 2019 in liver/kidney transplant recipient. <em>Transpl Infect Dis</em>. </span><a href="https://doi.org/10.1111/tid.14271"><span style="font-size: 10.0pt;">https://doi.org/10.1111/tid.14271</span></a></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify;"><span style="font-size: 10.0pt;"> </span></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">3.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Coe J., <strong>Puius, Y.</strong>, Jain, H., and Meyerowitz, E. (2024) Cervical lymphadenitis from <em>Mycobacterium avium</em> complex.<span style="mso-spacerun: yes;"> </span><em>BMJ Case Reports</em>.</span> <strong><span style="font-size: 10.0pt;">17</span></strong><span style="font-size: 10.0pt;">(3):e256726. <span style="mso-spacerun: yes;"> </span></span><a href="https://doi.org/10.1136/bcr-2023-256726"><span style="font-size: 10.0pt;">https://doi.org/10.1136/bcr-2023-256726</span></a></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify;"><span style="font-size: 10.0pt;"> </span></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">4.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Arora, S. and <strong>Puius, Y.A.</strong> (2023) Comment on: Community-Acquired Pneumonia.<span style="mso-spacerun: yes;"> </span><em>N Engl J Med</em> <strong>389</strong>(17): 1633. </span><a href="https://doi.org/10.1056/nejmc2310748"><span style="font-size: 10.0pt;">https://doi.org/10.1056/nejmc2310748</span></a></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify;"><span style="font-size: 10.0pt;"> </span></p>
<p class="MsoListParagraph" style="margin-left: .25in; text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">5.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Tsai, H., Minamoto, G.Y., and <strong>Puius, Y.A</strong>. (2023) "Chapter 36. Infections in Heart Transplantation" In: Barac, Y.D., Silvestry, S.C., Goldstein, D., Daneshmand M.A. eds. Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease. Wiley-Blackwell.</span></p>
<p class="MsoListParagraph" style="margin-left: .25in;"><span style="font-size: 10.0pt;"> </span></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span class="MsoHyperlink"><span style="font-size: 10.0pt; color: windowtext; text-decoration: none; text-underline: none;"><span style="mso-list: Ignore;">6.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Gould, C.V., Free, R.J., Bhatnagar, J. et al. (2023) Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation, United States, 2021 – Report of an Investigation. <em>Lancet Microbe</em>. <strong>4</strong>(9):e711-e721.<span style="mso-spacerun: yes;"> </span></span><a href="https://doi.org/10.1016/S2666-5247(23)00170-2"><span style="font-size: 10.0pt;">https://doi.org/10.1016/S2666-5247(23)00170-2</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">7.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Azar, M.M., Tsai, H., Vergidis, P., Harris, C.E., Anjan, S., Barros,N., Belga, S., Chuang, S.T., Czeresnia, J.M., Goel, S., Ince, D., Luk, A., Majeed, A., Multani, A., Obedi, K.M., and Swaminathan, N. (2023) <em>transplantid.net</em>:<span style="mso-spacerun: yes;"> </span>A Pilot Crowdsourced, Living, Online Library of Resources for the Teaching and Practice of Transplant Infectious Diseases. <em>Open Forum Inf Dis.</em></span> <strong><span style="font-size: 10.0pt;">10</span></strong><span style="font-size: 10.0pt;">(2):ofad081.</span> <a href="https://doi.org/10.1093/ofid/ofad081"><span style="font-size: 10.0pt;">https://doi.org/10.1093/ofid/ofad081</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span class="MsoHyperlink"><span style="font-size: 10.0pt; color: windowtext; text-decoration: none; text-underline: none;"><span style="mso-list: Ignore;">8.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Hemmige, V., Saeed, O., <strong>Puius, Y.A.</strong>, Azzi, Y., Colovai, A., Borgi, J., Goldstein, D.J., Rahmanian, M., Carlese, A., Jorde, U.P., and Patel, S. (2023)<span style="mso-spacerun: yes;"> </span>HIV D+/R+ heart/kidney transplantation: first case report. <em>J Heart Lung Transplant</em>.</span> <strong><span style="font-size: 10.0pt;">42</span></strong><span style="font-size: 10.0pt;">(3):406-408. </span><a href="https://doi.org/10.1016/j.healun.2022.11.004"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.healun.2022.11.004</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">9.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Maini, R., Saini, N., Bhavaan, K., Bharti, B., Walia, S., Kori N., Kataria S., Sharma P., Deswal V., Atluri, K., Mandke C, Chansoria M., Rawat, S.K., Bhat, R.S., Dravid, A., Barnawal, C., Sarkar N., Jariwala S., <strong>Puius, Y.A</strong>., Arora, S., Sethi, Y, for the MUNCO Registry. (2022) Clinico-epidemiologic characteristics of patients reported in the Mycotic infections in COVID-19 Registry. <em>Am J Trop Med Hygiene </em><strong>108</strong>(3):584-587<em>.</em> </span><a href="https://doi.org/10.4269/ajtmh.22-0503"><span style="font-size: 10.0pt;">https://doi.org/10.4269/ajtmh.22-0503</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">10.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Arora, S., Narayanan, S., Fazzari, M., Bhavana, K., Bhartendu, B., Walia, S., Kori N., Kataria S., Sharma P., Atluri, K., Mandke C, Gite, V., Redkar, N., Chansoria M., Rawat, S.K., Bhat, R.S., Dravid, A., Sethi, Y., Barnawal, C., Sarkar N.K., Jariwala S., Southern, W., <strong>Puius, Y.A.</strong>, MUNCO Registry (2022) Factors Associated with Mortality in Coronavirus-Associated Mucormycosis: Results from Mycotic Infections in COVID-19 (MUNCO) Online Registry. <em>J Clin Med</em>. <strong>11</strong>(23):7015.<span style="mso-spacerun: yes;"> </span></span><a href="https://doi.org/10.3390/jcm11237015"><span style="font-size: 10.0pt;">https://doi.org/10.3390/jcm11237015</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">11.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Castagna F., Xue X., Saeed O., et al. (2022) Hospital bed occupancy rate is an independent risk factor for COVID-19 inpatient mortality: a pandemic epicentre cohort study. <em style="mso-bidi-font-style: normal;">BMJ Open</em>. 12(2):e058171. </span><a href="https://doi.org/10.1136/bmjopen-2021-05817"><span style="font-size: 10.0pt;">https://doi.org/10.1136/bmjopen-2021-05817</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">12.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Thakkar, A., Cui, Z., Peeke, S.Z., et al. (2021) Patterns of leukocyte recovery predict infectious complications after CD19 CAR-T cell therapy in a real-world setting.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Stem Cell Investig</em>. 8:18. </span><a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8449156/"><span style="font-size: 10.0pt;">https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8449156/</span></a></…;
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">13.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Arora, S., Hemmige, V.S., Mandke, C., Chansoria, M., Rawat, S.K., Dravid, A., Sethi, Y., Medikeri, G., Jariwala, S.P., and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong> (2021) Online registry of COVID-19–associated mucormycosis cases, India, 2021. <em style="mso-bidi-font-style: normal;">Emerg Infect Dis</em>.<strong style="mso-bidi-font-weight: normal;">27</strong>(11) </span><a href="https://wwwnc.cdc.gov/eid/article/27/11/21-1322_article"><span style="font-size: 10.0pt;">https://wwwnc.cdc.gov/eid/article/27/11/21-1322_article</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">14.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Bartash, R. M., and Zingman, B. S. (2021) Maintaining Mask Momentum in Transplant Recipients.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Transplant Infectious Disease</em> <strong style="mso-bidi-font-weight: normal;">23</strong>(4): e13697. </span><a href="https://doi.org/10.1111/tid.13697"><span style="font-size: 10.0pt;">https://doi.org/10.1111/tid.13697</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">15.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Cervera Hernandez, M.E., Szymczak, W., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, and Shuter, J. (2021) Lung, Brain, and Spinal Cord Abscesses After a Near-Drowning Episode.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">American J. Med.</em> </span><a href="https://doi.org/10.1016/j.amjmed.2021.04.039"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.amjmed.2021.04.039</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">16.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Parkar, F., Tlamsa, A.P., Nistico, J.A., Muggia, V.A., Minamoto, G.Y., Jorde, U.P., Goldstein, D.J., and Moadel, R. (2021) Gallium-67 Single Photon Emission Computed Tomography Affects Management of Infections of Left Ventricular Assist Devices.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">ASAIO Journal. </em><strong style="mso-bidi-font-weight: normal;">67</strong>(7):<span style="mso-spacerun: yes;"> </span>746-751<span style="mso-spacerun: yes;"> </span></span><a href="https://doi.org/10.1097/mat.0000000000001316"><span style="font-size: 10.0pt;">https://doi.org/10.1097/mat.0000000000001316</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">17.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Muggia, V.A. and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong><span style="mso-spacerun: yes;"> </span>(2020) <em style="mso-bidi-font-style: normal;">Nocardia ignorata</em> Infection in Heart Transplant Patient.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Emerging Infectious Diseases</em> <strong style="mso-bidi-font-weight: normal;">26</strong>(11):2788-2789. </span><a href="https://doi.org/10.3201/eid2611.202756"><span style="font-size: 10.0pt;">https://doi.org/10.3201/eid2611.202756</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">18.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Nori, P., Szymczak, W., <strong style="mso-bidi-font-weight: normal;">Puius, Y</strong>., Sharma, A., Cowman, K., Gialanella, P., Fleischner, Z., Corpuz, M., Torres-Isasiga, J., Bartash, R., Felsen, U., Chen, V., and Guo, Y. (2020) Emerging Co-Pathogens: New Delhi Metallo-beta-lactamase producing <em style="mso-bidi-font-style: normal;">Enterobacterales</em> Infections in New York City COVID-19 Patients. <em style="mso-bidi-font-style: normal;">Int. J. Antimicrobial Agents</em> <strong style="mso-bidi-font-weight: normal;">56</strong>(6):106179<span style="mso-spacerun: yes;"> </span></span><a href="https://doi.org/10.1016/j.ijantimicag.2020.106179"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.ijantimicag.2020.106179</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">19.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Peraza, J. and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong> (2020) Cutaneous Fungal Infections in Left Ventricular Assist Device Recipients. <em style="mso-bidi-font-style: normal;">Current Fungal Infection Reports</em>.</span> <strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">14</span></strong><span style="font-size: 10.0pt;">:225–232 </span><a href="https://rdcu.be/b4HaA"><span style="font-size: 10.0pt; background: white; mso-highlight: white;">https://rdcu.be/b4HaA</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">20.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Zheng, C., Quintero, O. Revere, E.K., Oey, M.B., Espinoza, F., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, Ramirez-Baron, D., Salama, C.R., Hidalgo, L.F., Machado, F.S., Saeed, O., Shun, J., Patel, S.R., Coyle, C.M., and Tanowitz, H.B. (2020) Chagas Disease in the New York City Metropolitan Area.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Open Forum Infectious Diseases</em> <strong style="mso-bidi-font-weight: normal;">7</strong>(5):</span> <span style="font-size: 10.0pt;">ofaa156. </span><a href="https://doi.org/10.1093/ofid/ofaa156"><span style="font-size: 10.0pt;">https://doi.org/10.1093/ofid/ofaa156</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">21.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.,</span></strong><span style="font-size: 10.0pt;"> Aldrich, M., and Cope, J.R.<span style="mso-spacerun: yes;"> </span>(2020) “Acanthamoeba, Naegleria, & Balamuthia in Transplant patients: An Emerging Threat.” In: Morris, M., Kotton, C., Wolfe, C. (eds) Emerging Transplant Infections, pp. <span style="mso-spacerun: yes;"> </span>1451-1472 Springer, Cham, Switzerland.<span style="mso-spacerun: yes;"> </span></span><a href="https://link.springer.com/referenceworkentry/10.1007%2F978-3-030-01751-… style="font-size: 10.0pt; background: white; mso-highlight: white;">https://link.springer.com/referenceworkentry/10.1007%2F978-3-030-01751-…;
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">22.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Quintero Cardona, O., Hemmige, V., and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong><span style="mso-spacerun: yes;"> </span>(2020) Methenamine Hippurate May Have Particular Benefit in Preventing Recurrent Urinary Tract Infections in Diabetic Renal Transplant Recipients. <em style="mso-bidi-font-style: normal;">Transplant Infectious Diseases,</em> <strong style="mso-bidi-font-weight: normal;">22</strong>(2): e13247 </span><a href="https://doi.org/10.1111/tid.13247"><span style="font-size: 10.0pt;">https://doi.org/10.1111/tid.13247</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">23.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Jorde, U.P., Shah, A.M., Sims, D.B., Madan, S., Siddiqi, N., Luke, A., Saeed, O., Patel, S.R., Murthy S., Shin, J., Oviedo, J., Watts, S., Jakobleff, W., Forest, S., Vukelic, S., Belov, D., <strong style="mso-bidi-font-weight: normal;">Puius, Y.</strong>, Minamoto, G., Muggia, V., Carlese, A., Leung, S., Rahmanian, M., Leff, J., Goldstein, D. (2019) Continuous-flow left ventricular device survival improves with multidisciplinary approach.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Annals of Thoracic Surgery</em>. <strong style="mso-bidi-font-weight: normal;">108</strong>(2):508-516. </span><a href="https://doi.org/10.1016/j.athoracsur.2019.01.063"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.athoracsur.2019.01.063</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">24.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Patel S.R., Madan, S., Saeed, O., Sims D.B., Shin, J.J., Nucci, C., Borukhov, E., Goldstein, D.Y., Jakobleff, W., Forest, S., Vukelic, S., Murthy, S., Reinus, J., <strong style="mso-bidi-font-weight: normal;">Puius, Y</strong>., Goldstein, D.J., Jorde, U.P. (2018)<span style="mso-spacerun: yes;"> </span>Cardiac transplantation from non-viremic hepatitis C donors. <em style="mso-bidi-font-style: normal;">J Heart Lung Transplant</em>. <strong style="mso-bidi-font-weight: normal;">37</strong>(10): 1254-1260. </span><a href="https://doi.org/10.1016/j.healun.2018.06.012"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.healun.2018.06.012</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">25.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt; color: black;">Mogollón, J.E., Szymczak, W.A., Levi, M.H., Patel, H., and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A</strong>. (2018) Case #17015: Renal recipient with two weeks of progressive shortness of breath, fatigue, and bilateral lower extremity swelling. <em style="mso-bidi-font-style: normal;">Partners Infectious Disease Images</em>, </span><a href="https://www.idimages.org/idreview/case/?CaseID=544"><span style="font-size: 10.0pt;">https://www.idimages.org/idreview/case/?CaseID=544</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">26.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt; color: black;">Muggia, V.A., Minamoto, G.Y., Forest, S.J., Lerman, D.T., and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong> (2018)<span style="mso-spacerun: yes;"> </span>“Chapter 3:<span style="mso-spacerun: yes;"> </span>Left Ventricular Assist Device Infections: A Practical Approach.”<span style="mso-spacerun: yes;"> </span>In:<span style="mso-spacerun: yes;"> </span>Ventricular Assist Devices: Management, Outcomes and Complications.<span style="mso-spacerun: yes;"> </span>René Murielle, ed.<span style="mso-spacerun: yes;"> </span>Nova Science Publishers., Inc., Happauge, NY. </span><a href="https://novapublishers.com/wp-content/uploads/2019/01/978-1-53613-891-7… style="font-size: 10.0pt;">https://novapublishers.com/wp-content/uploads/2019/01/978-1-53613-891-7…;
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">27.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Kutner, A., Aldrich, M. Patel, S. Kang, J. J., Amin, B. Mann, R., Ali I. M., Brasil Martines, R., Cope, J. R., De Boccardo, G. O., and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong> (2018)<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Acanthamoeba</em> Endophthalmitis During Treatment for Cutaneous Disease in a Renal Transplant Patient.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Transplant Infectious Diseases</em>, <strong style="mso-bidi-font-weight: normal;">20</strong>(2):e12483 </span><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6110267/"><span style="font-size: 10.0pt;">http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6110267/</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">28.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Levy, D.T., Peck, N., Minamoto, G.Y., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, D’Alessandro, D.A., Goldstein, D. and Muggia, V.A.<span style="mso-spacerun: yes;"> </span>(2015)<span style="mso-spacerun: yes;"> </span>Role of gallium SPECT-CT in the diagnosis of left ventricular assist device infections:<span style="mso-spacerun: yes;"> </span>A case series and review of the literature.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">ASAIO Journal</em>, <strong style="mso-bidi-font-weight: normal;">61</strong>(1):<span style="mso-spacerun: yes;"> </span>e5-e10. </span><a href="https://doi.org/10.1097/mat.0000000000000167"><span style="font-size: 10.0pt;">https://doi.org/10.1097/mat.0000000000000167</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">29.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Levy, D.T., Guo, Y., Simkins, J., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, Muggia, V.A., Goldstein, D.J., D'Alessandro, D.A., and Minamoto, G.Y. (2014) Left ventricular assist device exchange for persistent infection: a case series and review of the literature. <em style="mso-bidi-font-style: normal;"><span style="color: black;">Transplant Infectious Diseases</span></em><span style="color: black;">, <strong style="mso-bidi-font-weight: normal;">16</strong>(3): 453-460. </span></span><a href="https://doi.org/10.1111/tid.12207"><span style="font-size: 10.0pt;">https://doi.org/10.1111/tid.12207</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt; font-variant: small-caps;"><span style="mso-list: Ignore;">30.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt; color: black;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt; color: black;">, Sonder, G. B., and Mileno, M. (2013)<span style="mso-spacerun: yes;"> </span>“Chapter 27:<span style="mso-spacerun: yes;"> </span>The Immunocompromised Traveler”<span style="mso-spacerun: yes;"> </span>In:<span style="mso-spacerun: yes;"> </span>Travel Medicine, 3<sup>rd</sup> Edition, Jay Keystone, Ed., pp. 265-272.<span style="mso-spacerun: yes;"> </span>Elsevier. </span><a href="https://www.sciencedirect.com/science/article/pii/B9781455710768000272"… style="font-size: 10.0pt;">https://www.sciencedirect.com/science/article/pii/B9781455710768000272<…;
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt; font-variant: small-caps;"><span style="mso-list: Ignore;">31.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt; color: black;">Irizarry-Acosta, M. and <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong> (2010) Post-influenza pneumonia:<span style="mso-spacerun: yes;"> </span>Everything old is new again.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Medicine and Health in Rhode Island,</em> <strong style="mso-bidi-font-weight: normal;">93</strong>: 204-211. </span><a href="http://www.rimed.org/medhealthri/2010-07/2010-07-204.pdf"><span style="font-size: 10.0pt;">http://www.rimed.org/medhealthri/2010-07/2010-07-204.pdf</span></a></p&…;
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">32.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt; color: black;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt; color: black;"> and Kalish, R.A. (2008) Lyme Arthritis:<span style="mso-spacerun: yes;"> </span>Pathogenesis, Clinical Presentation, and Management.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Infectious Disease Clinics of North America</em>, <strong style="mso-bidi-font-weight: normal;">22</strong>: 289-300. </span><a href="https://doi.org/10.1016/j.idc.2007.12.014"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.idc.2007.12.014</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">33.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt; color: black;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt; color: black;">, Shah, D.P., Brust, D.G., Dove, L.M., and Lefkowitch, J.H.<span style="mso-spacerun: yes;"> </span>(2008) Three Cases of Autoimmune Hepatitis in HIV Infected Patients.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Journal of Clinical Gastroenterology</em>, <strong style="mso-bidi-font-weight: normal;">42</strong>:<span style="mso-spacerun: yes;"> </span>425-429. </span><a href="https://doi.org/10.1097/01.mcg.0000225591.08825.3e"><span style="font-size: 10.0pt;">https://doi.org/10.1097/01.mcg.0000225591.08825.3e</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">34.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt; color: black;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt; color: black;"> and Snydman, D.R. (2007) Prophylaxis and treatment of CMV disease in recipients of solid organ transplants:<span style="mso-spacerun: yes;"> </span>Current approach and future challenges.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Current Opinion in Infectious Diseases</em> <strong style="mso-bidi-font-weight: normal;">20</strong>:<span style="mso-spacerun: yes;"> </span>419-424. </span><a href="https://doi.org/10.1097/qco.0b013e32821f6026"><span style="font-size: 10.0pt;">https://doi.org/10.1097/qco.0b013e32821f6026</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">35.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt; color: black;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt; color: black;"> and Scully, B. (2007) Treatment of <em style="mso-bidi-font-style: normal;">Candida albicans</em> pericarditis in a heart transplant patient.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Transplant Infectious Diseases</em> <strong style="mso-bidi-font-weight: normal;">9</strong>:<span style="mso-spacerun: yes;"> </span>229-232. </span><a href="https://doi.org/10.1111/j.1399-3062.2006.00195.x"><span style="font-size: 10.0pt;">https://doi.org/10.1111/j.1399-3062.2006.00195.x</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">36.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Stievater, T.H., and Srikrishnan, T. (2006) Crystal structure, conformation, and absolute configuration of kanamycin A.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Carbohydrate Research</em> <strong style="mso-bidi-font-weight: normal;">341</strong>:<span style="mso-spacerun: yes;"> </span>2871-2875. </span><a href="https://doi.org/10.1016/j.carres.2006.09.008"><span style="font-size: 10.0pt;">https://doi.org/10.1016/j.carres.2006.09.008</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">37.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt; color: black;">Dewan, J.C., Feeling-Taylor, A., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, Patskovska, L., Patskovsky, Y., Nagel, R.L., Almo, S.C., and Hirsch, R.E.</span> <span style="font-size: 10.0pt; color: black;">(2002) Structure of mutant human carbonmonoxyhemoglobin C (βE6K) at 2.0 Å resolution.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Acta Crystallographica</em> <strong style="mso-bidi-font-weight: normal;">D58</strong>:<span style="mso-spacerun: yes;"> </span>2038-2042. </span><a href="https://doi.org/10.1107/s0907444902016426"><span style="font-size: 10.0pt;">https://doi.org/10.1107/s0907444902016426</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">38.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><span style="font-size: 10.0pt;">Sarmiento, M., <strong style="mso-bidi-font-weight: normal;">Puius, Y.A.</strong>, Vetter, S.W., Keng, Y.-F., Wu, L., Zhao, Y., Lawrence, D.S., Almo, S.C., and Zhang, Z.-Y.<span style="mso-spacerun: yes;"> </span>(2000) Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Biochemistry</em> <strong style="mso-bidi-font-weight: normal;">39</strong>:<span style="mso-spacerun: yes;"> </span>8171-8179. </span><a href="https://doi.org/10.1021/bi000319w"><span style="font-size: 10.0pt;">https://doi.org/10.1021/bi000319w</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">39.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Fedorov, E.V., Eichinger, L., Schleicher, M., and Almo, S.C. (2000) Mapping the functional surface of domain 2 in the gelsolin superfamily.<span style="mso-spacerun: yes;"> </span><em style="mso-bidi-font-style: normal;">Biochemistry</em> <strong style="mso-bidi-font-weight: normal;">39</strong>:<span style="mso-spacerun: yes;"> </span>5322-5331. </span><a href="https://doi.org/10.1021/bi992364d"><span style="font-size: 10.0pt;">https://doi.org/10.1021/bi992364d</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">40.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Zou, M., Ho, N.T., Ho, C., and Almo, S.C. (1998) Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(α96Val</span><span style="font-size: 10.0pt; font-family: Cardo; mso-fareast-font-family: Cardo; mso-bidi-font-family: Cardo;">→Trp). </span><em style="mso-bidi-font-style: normal;"><span style="font-size: 10.0pt;">Biochemistry</span></em><span style="font-size: 10.0pt;"> <strong style="mso-bidi-font-weight: normal;">37</strong>:<span style="mso-spacerun: yes;"> </span>9258-65. </span><a href="https://doi.org/10.1021/bi9727287"><span style="font-size: 10.0pt;">https://doi.org/10.1021/bi9727287</span></a></p>
<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">41.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Mahoney, N.M., and Almo, S.C. (1998) The modular structure of actin-regulatory proteins.<em style="mso-bidi-font-style: normal;"> Current Opinion in Cell Biology </em><strong style="mso-bidi-font-weight: normal;"><span style="mso-spacerun: yes;"> </span>10:</strong> 23-34. </span><a href="https://doi.org/10.1016/s0955-0674(98)80083-5"><span style="font-size: 10.0pt;">https://doi.org/10.1016/s0955-0674(98)80083-5</span></a></p>
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<p class="MsoNormal" style="text-align: justify; text-indent: -.25in; mso-list: l0 level1 lfo1; border: none; mso-border-bottom-alt: solid black .5pt; padding: 0in; mso-padding-alt: 0in 0in 1.0pt 0in; margin: 0in 0in 12.0pt .25in;"><!-- [if !supportLists]--><span style="font-size: 10.0pt;"><span style="mso-list: Ignore;">42.<span style="font: 7.0pt 'Times New Roman';"> </span></span></span><!--[endif]--><strong style="mso-bidi-font-weight: normal;"><span style="font-size: 10.0pt;">Puius, Y.A.</span></strong><span style="font-size: 10.0pt;">, Zhao, Y., Sullivan, M., Lawrence, D.S., Almo, S.C., and Zhang, Z.-Y. (1997) Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. <em style="mso-bidi-font-style: normal;"><span style="mso-spacerun: yes;"> </span>Proceedings of the National Academy of Sciences of the U.S.A. </em><strong style="mso-bidi-font-weight: normal;"><span style="mso-spacerun: yes;"> </span>94:</strong> 13420-13425. </span><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc28320/"><span style="font-size: 10.0pt;">http://www.ncbi.nlm.nih.gov/pmc/articles/pmc28320/</span></a></p>
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<p>Yoram A. Puius, MD, PhD, is an attending physician, Associate Professor, Medicine and Associate Professor, Cardiothoracic & Vascular Surgery at Montefiore Einstein. His clinical focus centers on treating infections in the immunocompromised host, including recipients of solid organ transplants, patients with hematologic malignancies and recipients of cellular therapy.</p><p>After obtaining his Bachelor of Arts in physics from Cornell University in 1992, Dr. Puius earned his Doctor of Philosophy in biochemistry at Einstein in 1999, followed by his Doctor of Medicine in 2001. He moved to NewYork-Presbyterian Hospital-Cornell to complete his internal medicine residency in 2003 and an infectious diseases fellowship at NewYork-Presbyterian Hospital-Columbia in 2006. Following this, Dr. Puius completed an additional year focusing on infectious in the immunocompromised host at Tufts Medical Center in 2007.</p><p>Building on his clinical focus, Dr. Puius’s research involves infections in left ventricular assist device recipients, heart transplant recipients and kidney transplant recipients. In addition, he is the architect of the online transplant infectious disease library, “transplantid.net” for the American Society of Transplantation. He is also involved in research on COVID-19-associated Mucormycosis. Dr. Puius’s work has been published in numerous peer-reviewed journals, books, chapters and review articles, and he has presented abstracts and poster presentations nationally. He has been a reviewer for a number of journals and is on the editorial boards of <em>Clinical Transplantation</em> and <em>Transplant Infectious Diseases</em>.</p><p>Dr. Puius is board certified in Internal Medicine and Infectious Diseases. He is a member of many professional organizations, including the Infectious Diseases Society of America, the American Society of Transplantation and the International Society for Heart and Lung Transplantation. He is also the Founding Chair of the Transplant Infectious Diseases Online Library Working Group for the American Society of Transplantation. In 2021, Dr. Puius was named Heart Failure & Transplant Consultant of the Year at Montefiore. He has also been named in Castle Connolly’s “Top Doctors” for multiple years.</p>