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Current Research Projects

Active NIH Projects

The following table lists the Einstein Site PIs, grant numbers, and titles of NIH-funded projects collaborating with MRRC.

Einstein Site PIs Grant # Title
Carol Derby and Richard Lipton P01AG003949 (PIs: Derby, Lipton, Buxton) Einstein Aging Study
Roee Holtzer R01NS127697 Central control and neuroinflammatory mechanisms of locomotion in older adults with HIV
R01HL169316 The influence of asthma on walking in older adults: brain predictors, medication adherence and asthma control
Carmen Isasi R01 AG075758 (PI: Gonzalez) Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer’s Disease
1R01AG083894-01A1 (PI: DeCarli) Longitudinal MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of Latinos (SOL-INCA-MRI Long)
Mindy Katz U19AG076581 (PIs: De Erausquin, Gonzalez Aleman, Patterson, Seshadri, Katz) Interactions of SARS-CoV-2 infection and genetic variation on the risk of cognitive decline and Alzheimer’s disease in Ancestral and Admixed Populations
Matthew Abramowitz R01AR077042 Preserving physical function in patients with kidney disease.
R21AR087144 Scalable imaging approach to measure muscle bioenergetics in CKD
Tim Duong 5R01CA244768 MRI study of Chemobrain in pediatric oncology patients
David Zhu RF1AG084134 (PIs: Stowe, German, Zhang, Zhu) Biomarkers to Track Effective Interventions that Delay Dementia Onset in Participants of the "Risk Reduction for Alzheimer's Disease (rrAD)
R01AG076660 (PIs: Zhang, Vongpatanasin and Zhu) Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid and Tau in Older Adults (IPAT-Study).
R01NS129934 (PIs: Ding, Zhang, Zhu) Cerebral autoregulation, brain perfusion, and neurocognitive outcomes after traumatic brain injury (CAPCOG-TBI)
1R01AG092816-01A1 (PIs: Ding, Zhang) Community-based Aerobic Exercise in individuals with moderate and severe Traumatic Brain Injury (CAREx_TBI)
Sandra Aleksic 5K76AG083274 The Role of Hypothalamic Dysfunction in Accelerating Aging in Humans
U19AG078558 (PIs: Luchsinger, Nathan, Temprosa) Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project
Pierfilippo De Sanctis R01AG082188 Linking dementia pathology and alteration in brain activation to complex daily functional decline during the preclinical dementia stage
R01AG075679 (PI: Mahoney) Visual-Somatosensory Integration as a novel marker of Alzheimer’s Disease
Johanna Daily 1R01 NS123445-01 (PIs: Daily, Lipton) Characterizing persistent subclinical neurobehavioral effects of COVID-19 in a diverse urban population.
Kathryn Kirchoff U01NS102289 (PI: Selim) Statins Use in Intracerebral Hemorrhage Patients (SATURN)
David Hanna RM1DA063351 (PIs: Tien, Aouzerat, Hunt, Kizer, Riley, Wu) Stimulant and Polysubstance use, Inflammation, and Sex Effects on Myocardial Disease in HIV (SPISE-CMR)
1R01HL176336-01A1 (PI: Kizer) Progression of HIV-Associated Cardiac Fibro-Inflammation in Women
Jesus Anampa P01CA210961 (PIs: Esserman, Hylton-Watson) The I SPY 2.2 TRIAL: Evolving to Imaging and Molecular Biomarker Response Directed Adaptive Sequential Treatment to Optimize Breast Cancer Outcomes, Sub Project: I-SPY 2 TRIAL - Investigation of Serial Studies to Predict your Therapeutic Response with Imaging and Molecular Analysis 2

Other Projects

The following table lists the Einstein Site PIs, sponsors, and titles of other projects that have been approved for use of MRRC resources.

Einstein Site PIs Sponsor Title
Anampa, Condeelis, Oktay, Branch (MRI PI) EGL Lipper Foundation TMEM Doorway Activity Measurements by MRI (TDAM)
Gluck, Lauren Novartis/Neurox Protocol CLOU064, a double-blind randomized placebo controlled trial of the efficacy of Remibrutinib for treatment of Chronic Inducible Urticaria
Langston, Christopher Sanofi NeuroRx Sanofi Frexalimab Phase 2 Study in MS