Dmitry Fridman, M.D.

Generalist obstetrician-gynecologist with focus on minimally invasive gynecology and high risk obstetrics. Special interest in urogynecology and global health.

Fridman DB, Diagnosis of adenomyosis. PhD thesis. 2007,Saint-Petersburg,Russia. (Supervisors – professor Sergey Povzun, MD, PhD, professor Vitaly Bejenar, MD, PhD) .

Research was conducted in the fields of Pathology and Obstetrics and Gynecology. In this study different methods of adenomyosis biopsy diagnosis were compared. Their efficacy and possibility of early adenomyosis diagnosis were evaluated. The significant advantage of transcervical multiple puncture biopsy was established. A comparative morphological analysis of biopsy and hysterectomy specimens was conducted. From the data received it was determined that certain changes in myometrium are caused not by the invasion itself and are non-specific findings. Morphological substrate for sonographic findings in adenomyosis were analyzed. Changes in uterine lymphatic system caused by adenomyosis were described. Morphological changes in myometrium in early and late adenomyosis were compared  (early-stage adenomyosis was diagnosed with biopsy technique and late-stage adenomyosis was diagnosed after hysterectomy).

Fridman D, Steinberg E, Azhar E, Weedon J, Wilson TE, Minkoff H. Predictors of H1N1 vaccination in pregnancy. Am J Obstet Gynecol. 2011 Jun;204(6 Suppl 1): S124-7. Epub 2011 Apr 15.

The study is dedicated to analysis of factors influencing women’s decision to participate in vaccination against H1N1 infection during the outbreak autumn 2009. The Health Belief Model was utilized to identify these factors. It was found that perceived barriers to vaccination (p=0.001) and perceived severity of infection (p=0.018) were independent predictors of vaccination. The total predictive utility of the full model incorporating HBM dimensions, age, race, care provider and education level was moderate (area under the curve – 0.86). The conclusion of the study is that addressing perceived barriers (such as fear of side effects), explaining the safety of vaccine for the fetus, as well as stressing the complications associated with H1N1 infection in pregnancy may increase the rate of vaccination.

Fridman D, Kuzbari O, Minkoff H, Novel influenza H1N1 in pregnancy: a report of two cases. Infectious diseases in obstetrics and gynecology 2009:514353.

One of the first case-reports on H1N1 infection in pregnancy. The first case was complicated by acute respiratory distress syndrome, required intubation, and eventually died. The second patient had influenza H1N1 that did not have any major sequel. The article describes clinical presentation, diagnostic measures and management of patients with complicated course of H1N1 infection, suggests treatment and prophylactic algorithms.

Fridman DB, Bejenar VF, Povzun SA, Levitina EI, Analysis of efficacy obtaining histological specimens for adenomyosis verification. Journal of Obstetrics and Gynecology,Saint-Petersburg,Russia, 2005; V. LIV, 4: 91-8.

In this experimental study we analyzed different methods of obtaining histological specimen from myometrium. We compared their efficacy in obtaining specimen satisfactory for evalutation, risks of possible complications and efficacy in diagnosing adenomyosis. Study was included in main thesis of PhD.