Selected Publications, as of April, 2023:
Shi M, Han W, Loudig O, Shah C, Dobkin J, Keller S, Sadoughi A, Patel D, Desai A, Gombar S, Suh Y, Fernandez MK, DeLaRosa L, Wang T, Hosgood D, Pradhan K, Ye K, Spivack SD. (2023) Initial development and testing of an exhaled microRNA detection strategy for lung cancer case-control discrimination. [accepted, Scientific Reports, NPG]
Huang Z, Sun S, Lee M, Maslov AY, Shi M, Waldman S, Marsh A, Siddiqui T, Dong X, Peter Y, Sadoughi A, Shah C, Ye K, *Spivack SD, *Vijg J. Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking. Nat Genet. 2022 Apr;54(4):492-498. doi: 10.1038/s41588-022-01035-w. Epub 2022 Apr 11. PMID: 35410377. (*co-senior authors).
Cleven KL, Ye K, Zeig-Owens R, Hena KM, Montagna C, Shan J, Hosgood HD 3rd, Jaber N, Weiden MD, Colbeth HL, Goldfarb DG, Spivack SD++, Prezant DJ++ (++co-senior authors). Genetic Variants Associated with FDNY WTC-Related Sarcoidosis. Int J Environ Res Public Health. 2019 May 23;16(10). pii: E1830. doi: 10.3390/ijerph16101830. PMID:31126090.
Dong X, ShiN, LeeM, ToroR, Gravina S, Han W, Yasuda S, Wang T, Zhang Z, Vijg J, Suh Y, Spivack SD. (2018) Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung. Epigenetics 10.1080/15592294.2018.1441650, 2018.
Mullapudi N, Ye B, Suzuki M, Wang T, Fazarri M, Han W, Shi M, Marquardt G, Lin J, Wang T, Keller S, Zhu C, Locker J, Spivack SD. Genome-wide methylome alterations in lung cancer PLoS ONE, Dec. 2015.
Lin J, Marquardt G, Mullapudi N, Wang, T, Han W, Shi W, Zhu C, Keller S, Zhu C, Locker J, Spivack SD. Lung cancer transcriptomes refined with laser capture microdissection. Am J Pathology 06.028. 2014 .
Han W, Shi M, Spivack SD. Site-specific methylated reporter constructs for functional analysis of DNA methylation. Epigenetics 4; 8(11), 2013.
Shi M, Han W, Spivack SD. A quantitative method to identify miRNAs targeting an mRNA using a 3'UTR RNA affinity technique. Analytic Biochem 1;443(1):1-12, 2013.
Alberg AJ, Brock MV, Ford JG, Samet JM, Spivack, SD. Epidemiology of lung cancer. In Evidence-based Practice Guidelines. Diagnosis and Management of Lung Cancer (ACCP position statement). CHEST. May 2013;143(5 Suppl):e1S-e29S. doi: 10.1378/chest.12-2345. PMID: 23649439.
Tan XT, Marquardt G, Shi M, Han W, Spivack SD. High throughput library screening identifies phytochemical inducers of phase II mutagen/oxidant metabolism enzymes GSTP1 and NQO1 in human lung cells. Am J Resp Cell Molec Biol, 46(3): 365-71, 2012.
Brock GJ, Moschos S, Spivack SD, Hurteau GJ. The 3' prime paradigm of the miR-200 family and other microRNAs. Epigenetics (6:3, 1-5), 2011.
Tan XT, Shi M, Minna JD, Han W, Spivack SD. Candidate phytopreventive agent modulation of phase II metabolism enzymes GSTP1 and NQO1 in human bronchial cells. J Nutrition, 140(8): 1404-10, 2010.
Tan, XT, Wang T, Xiong S, Kumar SV, Han W, Spivack SD. Smoking-related gene expression in laser capture microdissected human lung. Clin Cancer Res, 15(24): 7562-70, 2009.
Han W, Tang T, Reilly AA, Keller S, Spivack SD. Gene promoter methylation analyses from exhaled breath, with differences in smokers and lung cancer cases. Resp Res, 10:86 epubl, 2009.
Tan X-L, Moslehi R, Han W, Spivack SD. Haplotype tagging single nucleotide polymorphisms in the glutathione S-transferase P1 gene promoter and susceptibility to lung cancer. Cancer Detection Prev,32:403-415, 2009.
Tan X-L, Spivack SD. Dietary chemoprevention strategies for induction of phase II metabolism: a review. Lung Cancer,65(2):129-37, 2009.
Hurteau GJ, Carlson AJ, Spivack, SD, Brock GJ. Restoration of E-Cadherin expression by over-expression of the microRNA hsa-miR-200c via reduced expression of the transcription factor TCF8. Cancer Res. 67:7972-76, 2007.
Hurteau, GJ, Spivack SD, Brock G. Parallel identification of miRNA and target mRNA by combined informatics and qRT-PCR approaches: application to has-miR-200c. Cell Cycle 5(17):1951-56, 2006.
Han W, Cauchi S, Herman JG, Spivack SD. Methylation mapping of DNA by tag-modified bisulfite genomic DNA sequencing. Analytic Biochem. 355: 50-61, 2006.
Cauchi S, Han W, Kumar SV, Spivack SD. Haplotype-environment interactions regulating the human GSTP1 promoter Cancer Res. 66(12): 6439-6448, 2006.
Kumar SV, Hurteau GJ, Spivack SD. Validity of mRNA expression analyses of human saliva. Clin. Cancer Res. 12: 5033-39, 2006.
Spivack SD, Hurteau GJ, Jain R, Kumar SV, Aldous KM, Gierthy JF, Kaminsky LS. Gene-environment interaction signatures by quantitative mRNA profiling in exfoliated buccal mucosal cells. Cancer Res, 64:6805-6813, 2004.
Spivack SD, Hurteau GJ, Fasco MJ, Kaminsky LS. Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors. Clinical Cancer Research, 9:6002-6011, 2003.
