Acyl CoA Analysis
This LC/MS/MS module includes acetyl CoA, malonyl CoA, and succinyl CoA, in order to interface with acyl carnitine analysis in Module #1, and TCA cycle measurements in Modules # 3 and 7, with a standard curve for each of the metabolites for absolute quantification. For examples of this module’s utility for Core customers, see:
Vaitheesvaran, B., Yang, L., Hartil, K., Glaser, S., Yazulla, S., Bruce, J. E. & Kurland, I. J. Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation, PLoS One. 7, e33717.
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