Phosphorus Metabolism | Montefiore Einstein

Maria Ajaimy, MD, earned her medical degree at Lebanese University School of Medicine in Beirut, Lebanon. She completed a clinical fellowship in the Renal Division at SUNY downstate, NY, followed by a clinical transplant fellowship in the Renal Division at BIDMC, Harvard teaching hospital. Dr. Ajaimy is a UNOS certified transplant nephrologist and brings to Montefiore more than a decade of expertise in kidney and kidney-pancreas transplantation. Dr. Ajaimy is board certified by the American Board of Internal Medicine and the American Board of Nephrology. Dr. Ajaimy is a member of several societies. She has been the principal investigator in several trials and has written numerous articles on complex issues in kidney transplantation.

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Matthew K. Abramowitz

Read more about Matthew K. Abramowitz

Matthew K. Abramowitz

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Provider

Faculty

First Name

Matthew

Last Name

Abramowitz

NPI

1619115524

Faculty ID

10444

CMO Specialties

Nephrology

Clinical Terms

Acute Kidney Injury

Proteinuria

Chronic Kidney Disease

Acute Inflammation Of The Kidney

Abnormally High Levels Of Nitrogen

Decline In Renal Filtration Function

Decreased Alertness

Defective Bone Development

Dystrophic Growth Of The Bone

Elevated Bun

Elevated Creatinine

Elevated Creatinine & Bun

Elevated Kidney Function Test

Elevation Of Blood Urea

Elevation Of Blood Urea Nitrogen

End Stage Renal Disease

Enhanced Reabsorption Of Urea

ESRD

General/Other

Glomerular Disease

Heart-Disease Related

Creatinine (Elevated)

Bilateral Renal Agenesis

Bladder Calculi

Bladder Calculus

Bladder Stone

Bun & Creatinine (Elevated)

Bun (Elevated)

Calcium Disturbance

Calcium Oxalate Calculi

Calcium Oxalate Stone

Calcium Phosphate Calculi

Calcium Phosphate Stone

Calculus Of Bladder

Calculus Of Kidney

Cardiac/Renal Disease

CKD

Consult For Dialysis

Cystine Calculi

Acute Glomerulonephritis

Kidney Cancer

Kidney Infection

Kidney Stones

Insufficient Urine Production

Kidney (Sudden Loss Of Function)

Kidney Dialysis

Kidney Function Test (Elevated)

Kidney Inflammation (Acute)

Kidney Inflammtion

Kidney Transplant (Completed)

Kidney Transplant (Needed)

Kidney Trauma

Loken Senior Syndrome

Loss Of Kidney Function (Sudden)

Metabolic Bone Disease

Oliguric Renal Failure

Unilateral Renal Agenesis

Transplant Disease

Transplant Bone Disease

Thrombotic Thromboytopenic Purpura

Thin Basement Membrane Nephropathy

Thin Basement Membrane Disease

Sudden Loss Of Kidney Funtion

Stone In Kidney

Stone In Bladder

Renal/Cardiac Disease

Renal Stone Disease

Renal Stone

Renal Replacement Therapy

Staghorn Calculus

Pain In Kidney

Phosphorus Metabolism

Post-Hospital Discharge

Post-Hospital Discharge AKI

Renal Artery Stenosis

Alkalosis

Pyelonephritis

Oliguric Kidney Failure

Electrolyte Abnormality

Kidney Problem

Kidney/Heart Disease

Employment Status

Full Time

Patient Type

Adult

Department

einstein-dept-medicine

Gender

Male

matthew.abramowitz@einsteinmed.edu

Phone

718-430-8566

Titles

Type

Academic

Department

Department of Medicine

Department Link

Rank

Professor

Division

Nephrology

Locations

Is Primary

Type

Clinical

Location (Address, State, City, Zip)

Not used, will be deleted

Coordinates

POINT (-73.88072 40.88002)

Address Line 1

111 East 210th Street

City

Bronx

State

Zip

10461-2401

Location Title

Montefiore Medical Center

Is Primary

Off

Type

Academic

Location (Address, State, City, Zip)

Not used, will be deleted

Coordinates

POINT (-73.8459022 40.8504961)

Building

Block

Room

211

Address Line 1

Albert Einstein College of Medicine

Address Line 2

Jack and Pearl Resnick Campus

Address Line 3

1300 Morris Park Avenue

City

Bronx

State

Zip

10461

Location Title

Albert Einstein College of Medicine

Education and Trainings

Education Type Label

Medical Education

Education Institution

Albert Einstein College of Medicine

Education Type Label

Fellowship

Education Institution

Montefiore Medical Center

Education Type Label

Residency

Education Institution

Montefiore Medical Center

Professional Interests

Matthew Abramowitz, M.D., M.S. completed his medical education at the Albert Einstein College of Medicine and internal medicine residency at Montefiore Medical Center, where he was a Chief Resident.  He remained at Einstein/Montefiore for nephrology fellowship and earned a Masters in Clinical Research through Einstein’s Clinical Research Training Program.  He is currently Associate Professor of Medicine at Einstein.  He is the recipient of a Career Development Award from the Einstein/Montefiore Institute for Clinical and Translational Research, a Carl Gottschalk Research Scholar Grant from the American Society of Nephrology, and K23 and R01 awards from the National Institutes of Health.
Dr. Abramowitz’s research focuses on the effects of chronic kidney disease on skeletal muscle physiology and physical function. Additional interests include chronic metabolic acidosis, including its sequelae and treatment approaches in patients with chronic kidney disease. His work employs both observational and interventional study designs and translational methods including skeletal muscle biopsies and transcriptomic analysis of skeletal muscle. Current areas of investigation include pathology his group has identified in adults with chronic kidney disease: altered muscle regeneration and fibrosis, and gait abnormalities which associate with fall risk and cognitive impairment.

Research Areas

Physical function impairment in chronic kidney disease, skeletal muscle fibrosis, gait abnormalities, metabolic acidosis, accelerated aging

Research Profile

https://einsteinmed.edu/faculty/10444/Matthew-Abramowitz

Clinical Profile

https://montefioreeinstein.org/profiles/1619115524/matthew-k-abramowitz

CHAM Provider

Off

Professional Title

M.D.

M.S.

Clinical Focus

Acute Kidney Injury Acid-Base Disorders Chronic Kidney Disease Hemodialysis

Research Focus

Dr. Abramowitz’s main research interest is investigating mechanisms of physical function impairment in people with kidney disease, including skeletal muscle pathology, metabolic acidosis, and gait disturbances. His research employs a wide range of patient-oriented research tools, including wearable technologies, state-of-the-art methods to study human physiology and metabolism, prospective collection of biospecimens including tissue samples, and linkage with clinical patient data. 

Elsevier Profile

https://einstein.pure.elsevier.com/en/persons/013eb072-c3b8-4668-b12c-eb3690c26…

Selected Publications

Shah SN, Abramowitz M, Hostetter TH, Melamed ML. Serum bicarbonate levels and the progression of kidney disease: a cohort study.  American Journal of Kidney Diseases 2009 Aug;54(2):270-277
Abramowitz M, Muntner P, Coco M, Southern W, Lotwin I, Hostetter TH, Melamed ML. Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization. Clinical Journal of the American Society of Nephrology 5: 1064-1071, 2010
Bauer C, Abramowitz M, Hostetter TH. Is angiotensin blockade indicated in the elderly? Nature Reviews Nephrology 2010 Jan; 6(1): 11-12
Abramowitz MK, Hostetter TH, Melamed ML. Association of serum bicarbonate levels with gait speed and quadriceps strength in older adults. American Journal of Kidney Diseases 58: 29-38, 2011
Skversky AL, Kumar J, Abramowitz MK, Kaskel FJ, Melamed ML. Association of glucocorticoid use and low 25-hydroxyvitamin D levels: results from the National Health and Nutrition Examination Survey (NHANES): 2001-2006. J Clin Endocrinol Metab 96:3838-3845, 2011
Turner J, Bauer C, Abramowitz MK, Melamed ML, Hostetter TH. Treatment of chronic kidney disease. Kidney Int 81: 351-362, 2012
Abramowitz MK, Hostetter TH, Melamed ML. Lower serum bicarbonate and a higher anion gap are associated with lower cardiorespiratory fitness in young adults. Kidney Int 81:1033-42, 2012
Abramowitz MK, Hostetter TH, Melamed ML. Serum anion gap, kidney function, and mortality in US adults. Kidney Int 82: 701-709, 2012
Abramowitz MK, Melamed ML, Bauer C, Raff AC, Hostetter TH. Effects of oral sodium bicarbonate in patients with CKD. Clinical Journal of the American Society of Nephrology 8:714-20, 2013
Chen W, Abramowitz MK. Treatment of Metabolic Acidosis in Patients with Chronic Kidney Disease. American Journal of Kidney Diseases 63: 311-317, 2014
Amodu A, Abramowitz MK. Dietary acid, age, and serum bicarbonate levels among adults in the United States. Clinical Journal of the American Society of Nephrology 8:2034-42, 2013
Chen W, Abramowitz MK. Metabolic acidosis and the progression of chronic kidney disease. BMC Nephrology 15:55, 2014  
Abramowitz MK. Acid-base balance and physical function. Clinical Journal of the American Society of Nephrology, 9:2030-2, 2014
Sharma D, Hawkins M, Abramowitz MK. Association of sarcopenia with eGFR and misclassification of obesity in adults with chronic kidney disease in the United States. Clinical Journal of the American Society of Nephrology, 9:2079-88, 2014
Chen W, Melamed ML, Abramowitz MK. Serum bicarbonate and bone mineral density in United States adults. American Journal of Kidney Diseases, 65:240-248, 2015
Huston HK, Abramowitz MK, Zhang Y, Greene T, Raphael KL. Net endogenous acid production and mortality in NHANES III. Nephrology, 20:209-15, 2015
Sarathy H, Pramanik V, Kahn J, Abramowitz MK, Meier K, Kishore P, Melamed ML. The effects of short-term vitamin D supplementation on glucose metabolism in dialysis patients: a systematic review and meta-analysis.  Int Urol Nephrol, 47:537-49, 2015
Patel R, Paredes W, Hall CB, Nader MA, Sapkota D, Folkert VW, Abramowitz MK. Variability in monthly serum bicarbonate measures in hemodialysis patients: a cohort study. BMC Nephrology, 16:214, 2015
Sarathy H, Henriquez G, Abramowitz MK, Kramer H, Rosas SE, Johns T, Kumar J, Skversky A, Kaskel FJ, Melamed ML. Abdominal Obesity, Race and Chronic Kidney Disease in Young Adults: Results from NHANES 1999-2010. PLOS One, 11(5): e0153588, 2016
Liang E, Rodriguez M, Mueller M, Abramowitz MK, Mokrzycki MH. Outcomes associated with a heparin-free hemodialysis protocol and review of the literature. Journal of Clinical Nephrology and Renal Care, 2:010, 2016
Chen W, Melamed ML, Hostetter TH, Bauer C, Raff AC, Almudevar AL, Lalonde A, Messing S, Abramowitz MK. Effect of Oral Sodium Bicarbonate on Fibroblast Growth Factor-23 in Patients with Chronic Kidney Disease: A Pilot Study. BMC Nephrology, 17:114, 2016
Abramowitz MK, Sharma D, Folkert VW. Hidden obesity in dialysis patients: clinical implications. Seminars in Dialysis, 29:391-395, 2016
Androga L, Sharma D, Amodu A, Abramowitz MK. Sarcopenia, obesity, and mortality in US adults with and without chronic kidney disease. Kidney International Reports, 2:201-211, 2017
Blanco I, Labitigan M, Abramowitz MK. The Association Between Anti-Nuclear Antibodies and Obesity is Likely Mediated by Abdominal Adiposity and Systemic Inflammation. Journal of Clinical & Cellular Immunology, 8:4, 2017
Abramowitz MK. HCO3 balance and prescription in ESRD. Journal of the American Society of Nephrology, 28:726-734, 2017
Abramowitz MK, Hall CB, Amodu A, Sharma D, Androga A, Hawkins M. Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study. PLOS One, 13(4): e0194697, 2018
Chen W, Anokhina V, Miller B, Dieudonne G; Abramowitz MK, Kashyap R, Yan C, Wu TT, Bentley KL, Bushinsky DA. Patients with Advanced Chronic Kidney Disease and Vascular Calcification Have a Large Hydrodynamic Radius of Secondary Calciprotein Particles. Nephrology Dialysis Transplantation, 34(6):992-1000, 2019
Scialla JJ, Brown L, Gurley S, Corcoran DL, Bain JR, Muehlbauer MJ, O’Neal SK, O’Connell T, Wolf M, Melamed ML, Hostetter TH, Abramowitz MK. Metabolic impact of base-loading in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 13:1244-1246, 2018
Abramowitz MK. Metabolic Acidosis and Cardiovascular Disease Risk in CKD. Clinical Journal of the American Society of Nephrology, 13:1451-1452, 2018
Lee JA, Abramowitz MK, Kipperman N, Drzewiecki BA, Melamed ML, Stern JM. Exploring the Association of Asthma with Urinary Stone Disease: Results from the National Health and Nutrition Examination Survey 2007-2014. European Urology Focus, 2018 Aug 7 epub ahead of print
Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon H, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS. Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease. American Journal of Physiology - Renal Physiology. 315(6):F1658-1669, 2018
Watts KL, Srivastava A, Lin W, Schoenfeld D, Abramowitz M, Stern JM: Baseline chronic kidney disease does not predict long-term renal functional decline after percutaneous nephrolithotomy. Urolithiasis, 2019 Feb 12, epub ahead of print
Tran J, Ayers E, Verghese J, Abramowitz MK. Gait abnormalities and the risk of falls in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 14:983-993, 2019
Chen W, Eisenberg R, Mowrey WB, Wylie-Rosett J, Abramowitz MK, Bushinsky DA, Melamed ML. Association between dietary zinc intake and abdominal aortic calcification in US adults. Nephrology Dialysis Transplantation, 2019 Jul 11, Epub ahead of print
Melamed ML, Horwitz EJ, Dobre MA, Abramowitz MK, Zhang L, Lo Y, Mitch WE, Hostetter TH. The effects of sodium bicarbonate in chronic kidney disease stages 3 and 4: a randomized, placebo-control, multi-center clinical trial. American Journal of Kidney Diseases, 75(2):225-234, 2020
Ho JQ, Verghese J, Abramowitz MK. Walking while talking in older adults with chronic kidney disease. Clinical Journal of the American Society of Nephrology, 15(5):665-672, 2020
Abramowitz MK. Defining acid-base status in hemodialysis – is bicarbonate enough? Kidney Medicine, 2(1):1-2, 2020
Park S, Paredes W, Custodio M, Goel N, Sapkota D, Bandla A, Lynn RI, Reddy SM, Hostetter TH, Abramowitz MK. Intradialytic acid-base changes and organic anion production during high versus low bicarbonate hemodialysis. American Journal of Physiology - Renal Physiology, 318(6):F1418-F1429, 2020
Brown DD, Roem J, Ng DK, Reidy KJ, Kumar J, Abramowitz MK, Mak RH, Furth SL, Schwartz GJ, Warady BA, Kaskel FJ, Melamed ML. Low serum bicarbonate and CKD progression in children. Clinical Journal of the American Society of Nephrology, 15(6):755-765, 2020
Koren MJ, Blumen HM, Ayers EI, Verghese J, Abramowitz MK. Cognitive dysfunction and gait abnormalities in CKD. Clinical Journal of the American Society of Nephrology, 16(5):694-704, 2021
Lambert DC, Abramowitz MK. Obesity and the Risk of Low Bicarbonate: A Cohort Study. Kidney Medicine, published online April 15, 2021

EMR ID

4420

Biography

Matthew Abramowitz, M.D., M.S. completed his medical education at the Albert Einstein College of Medicine and internal medicine residency at Montefiore Medical Center, where he was a Chief Resident. He remained at Einstein/Montefiore for nephrology fellowship and earned a Master’s in Clinical Research through Einstein’s Clinical Research Training Program. He is currently Professor of Medicine (Nephrology) at Einstein, Scientific Director of the Clinical Research Center and the Advanced Biomarker and Biorepository Core within the Einstein-Montefiore Institute for Clinical and Translational Research, and Scientific Director of the Cancer Biorepository Shared Resource within the Montefiore Einstein Cancer Center. Dr. Abramowitz is a practicing nephrologist and physician-scientist whose research focuses on understanding the causes of impaired physical function in patients with chronic kidney disease. His research has been funded by the Einstein/Montefiore Institute for Clinical and Translational Research, the American Society of Nephrology, and the National Institutes of Health.

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