James M. Tauras
<p>My major interests are teaching cardiology to trainees of all levels, as well as researching different teaching techniques. Areas of clinical expertise are congestive heart failure and echocardiography. </p>
<p>Jim Tauras, MD, FACC, is a cardiologist, Assistant Professor, Medicine and
Course Director,Cardiovascular Diseases Physiology and Pathophysiology at
Montefiore Einstein. Dr. Tauras’ major clinical interests include critical
care cardiology, congestive heart failure and cardiac amyloidosis.
</p><p>After obtaining his Bachelor of Science in biological engineering from Cornell
University in 1995, Dr. Tauras earned his Doctor of Medicine at Weill Cornell
Medical College in 2003. He then came to Montefiore Einstein to complete an
internal medicine internship in 2004, an internal medicine residency in 2006
and a cardiology fellowship in 2009.
</p><p>Dr. Tauras has been site principal investigator for multiple national and
international clinical trials regarding novel therapeutics for acute heart
failure and cardiac amyloidosis. His work has been published in numerous
peer-reviewed journals, books, chapters, review articles and abstracts, and he
has given several invited presentations.
</p><p>Dr. Tauras is board certified by the American Board of Internal Medicine in
Cardiovascular Diseases. He is a Fellow of the American College of Cardiology.
</p>
Daniel B. Sims
<p class="MsoNormal">Daniel Sims, MD, FAHA, FACC, serves as the Program Director of the Cardiology Fellowship Training Program and is the Medical Director of the Moses Cardiac Intensive Care Unit (CICU). Dr. Sims is an Associate Professor of Medicine, Fellow of the American Heart Association (AHA), and Fellow of the American College of Cardiology (ACC). Originally from Bellmore, NY, Dr. Sims graduated from Yale University with a BA in history in 1999. He attended medical school at Emory University School of Medicine in Atlanta, GA, graduating in 2003. He stayed at Emory for his 3-year internal medicine internship and residency training, finishing in 2006. He was selected to stay an additional one year to serve as the chief resident at the Emory University Hospital. Dr. Sims did his 3-year cardiology fellowship at Columbia University Medical Center and served as chief cardiology fellow during his final year, finishing in 2010. He completed an additional one-year advanced heart failure and transplant cardiology fellowship at Columbia in 2011. Dr. Sims returned to Emory to serve on the cardiology faculty and as a member of the Center for Heart Failure Therapy and Transplantation.</p>
<p class="MsoNormal">After 2 years, Dr. Sims was recruited to Montefiore in 2013 to be the Medical Director for the Moses CICU and a member of the cardiac transplant and left ventricular assist device (LVAD) team. At Montefiore, Dr. Sims has been active in clinical research involving heart failure, cardiogenic shock, cardiac critical care, cardiac transplantation, and LVADs. He has mentored numerous residents and fellows on research projects. Dr. Sims served 2 2-year terms as a member of the AHA’s Acute Cardiac Care Committee and has been a member of the AHA writing groups for scientific statements on neuroprognostication after cardiac arrest, management of fulminant myocarditis, the prevention of complications in the CICU, and escalating and de-escalating temporary mechanical circulatory support devices. Dr. Sims is a two-time winner of the Department of Medicine’s Sharon R. Silbiger Faculty Teaching Award as the subspecialist of the year. Prior to becoming Program Director, Dr. Sims was a two-time winner of the Cardiology Fellowship Training Program “Program Director’s Training Award.” Dr. Sims is board certified in Cardiology as well as in Advanced Heart Failure and Transplant Cardiology. </p>
Dr. Sim's clinical focus has been the treatment of patients with acute and chronic heart failure due to multiple kinds of cardiomyopathy such as dilated, hypertrophic and restrictive, among others.
Dr. Sims’ research focuses on a number of topics, including the delivery of cardiac critical care and improving outcomes in the CICU and the use of temporary mechanical circulatory support with intra-aortic balloon pumps, Impella, percutaneous heart pumps, extracorporeal membrane oxygenation (ECMO) pumps and other devices to treat cardiogenic shock. He also aims to improve left ventricular assist device patient and heart transplant patient survival.
<p>Daniel Sims, MD, serves as the Program Director of the Cardiology Fellowship Training Program and is the Medical Director of the Moses Cardiac Intensive Care Unit (CICU). Dr. Sims is an Associate Professor of Medicine at our Albert Einstein College of Medicine, Fellow of the American Heart Association (AHA), and Fellow of the American College of Cardiology (ACC). Originally from Bellmore, NY, Dr. Sims graduated from Yale University with a BA in history in 1999. He attended medical school at Emory University School of Medicine in Atlanta, GA, graduating in 2003. He stayed at Emory for his 3-year internal medicine internship and residency training, finishing in 2006. He was selected to stay an additional one year to serve as the chief resident at the Emory University Hospital. Dr. Sims did his 3-year cardiology fellowship at Columbia University Medical Center and served as chief cardiology fellow during his final year, finishing in 2010. He completed an additional one-year advanced heart failure and transplant cardiology fellowship at Columbia in 2011. Dr. Sims returned to Emory to serve on the cardiology faculty and as a member of the Center for Heart Failure Therapy and Transplantation.</p><p>After 2 years, Dr. Sims was recruited to Montefiore in 2013 to be the Medical Director for the Moses CICU and a member of the cardiac transplant and left ventricular assist device (LVAD) team. His clinical focus has been the treatment of patients with acute and chronic heart failure due to multiple kinds of cardiomyopathy such as dilated, hypertrophic, and restrictive, among others. Dr. Sims also cares for patients with myocarditis, left ventricular assist devices, and cardiac transplants.</p><p>Dr. Sims has been active in clinical research involving heart failure, cardiogenic shock, temporary mechanical circulatory support devices, cardiac critical care, cardiac transplantation, and LVADs. He has mentored numerous residents and fellows on research projects and his work has been published in a number of peer-reviewed journals and textbooks. Dr. Sims served 2 2-year terms as a member of the AHA’s Acute Cardiac Care Committee and has been a member of the AHA writing groups for scientific statements on neuroprognostication after cardiac arrest, management of fulminant myocarditis, the prevention of complications in the CICU, and escalating and de-escalating temporary mechanical circulatory support devices. Dr. Sims is a two-time winner of the Department of Medicine’s Sharon R. Silbiger Faculty Teaching Award as the subspecialist of the year. Prior to becoming Program Director, Dr. Sims was a two-time winner of the Cardiology Fellowship Training Program “Program Director’s Training Award.” Dr. Sims is a member of the AHA, the ACC, and the International Society of Heart and Lung Transplantation. Additionally, he is board certified in Cardiology as well as Advanced Heart Failure and Transplant Cardiology.</p>
Jooyoung (Julia) Shin
<p align="left" style=" word-break: normal; text-align: left;"><span style=" color: black; font-size: 12.0pt; font-family: 'Times New Roman';">Clinical cardiology, specifically end-stage congestive heart failure, mechanical circulatory support, and cardiac transplantation.  </span></p>
Dr. Shin's clinical focus is on caring for patients with heart failure, particularly providing expertise in advanced heart failure, heart transplantation, and mechanical circulatory support.
Heart failure treatment is the primary focus of Dr. Shin’s research. She is the site principal investigator for the effectiveness of omecamtiv mecarbil/AMG 423 to treat chronic heart failure with reduced ejection fraction (GALACTIC-HF) and multiple cardiac sensors for the management of heart failure (MANAGE-HF) trials.
<p>Jooyoung Julia Shin, MD, is Fellowship Director, Advanced Heart Failure and Transplant Cardiology Fellowship Program and Associate Professor, Medicine at Montefiore Einstein. Dr. Shin’s clinical focus centers on heart failure, cardiac transplantation and mechanical circulatory support.</p><p>After obtaining her Bachelor of Science from the University of Michigan in 1994, Dr. Shin earned her Doctor of Medicine at George Washington University in 1999. She completed an internship and residency in internal medicine at the University of Maryland in 2002 before completing a cardiovascular disease fellowship at Emory University in 2005. Following this, Dr. Shin remained at Emory to complete an additional fellowship in advanced heart failure and transplant cardiology in 2006.</p><p>Dr. Shin’s research focuses on fellow education. She has been principal investigator and co-principal investigator on several funded research projects, and she has presented at invited lectures nationwide. Her work has also been published in numerous peer-reviewed journals, and she has been a reviewer for scientific publications, including the <em>Mayo Clinic Proceedings</em>, the <em>American Journal of Cardiology</em> and <em>Pacing and Clinical Electrophysiology</em>, among others.</p><p>Dr. Shin is board certified by the American Board of Internal Medicine in Cardiovascular Disease, Internal Medicine and Advanced Heart Failure and Transplant Cardiology. She is a member of the American College of Cardiology and the International Society for Heart and Lung Transplantation.</p>
Omar Saeed
<p>Heart Failure</p>
<p>Cardiac Transplantation</p>
<p>Mechanical Circulatory Support</p>
<p>Hemolysis</p>
<p> </p>
<p><strong>Education and Training</strong></p>
<p>College: University of California, Berkeley</p>
<p>Medical School: New York Medical College</p>
<p>Residency: Emory University Hospital</p>
<p>Fellowships: Emory University Hospital, Montefiore Medical Center/Albert Einstein College of Medicine</p>
<p> </p>
<p><strong>Grant Support</strong></p>
<p>Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory Support (NIH/NHLBI K23HL145140, PI: Saeed)</p>
<p>Jan 2019-Dec 2023</p>
<p> </p>
<p> </p>
Dr. Saeed's clinical focus is on heart failure, heart transplantation and mechanical circulatory support.
Dr. Saeed’s research focuses on the mechanisms of hematological and neurological adverse events during mechanical circulatory support.
<p align="LEFT">1. <strong>Saeed O, </strong>Jakobleff WA, Forest SJ, Chinnadurai T, Mellas N, Rangasamy S, Xia Y, Madan S, Acharya P, Algodi M, Patel SR, Shin J, Vukelic S, Sims DS, Reyes Gil M, Billett HH, Kizer JR, Goldstein DJ, Jorde UP. Hemolysis and Non Hemorrhagic Stroke during Venoarterial Extracorporeal Membrane Oxygenation. The Annals of Thoracic Surgery, 2019.</p>
<p align="LEFT">2. Acharya P, Jakobleff WA, Forest SJ, Chinnaduria T, Mellas N, Patel SR, Kizer JR, Billett HH, Goldstein DJ, Jorde UP, <strong>Saeed O</strong>. Fibrinogen Albumin Ratio and Ischemic Stroke during Venoarterial Extracorporeal Membrane Oxygenation. ASAIO J. 2019.</p>
<p align="LEFT">3. Jorde UP, Shah A, Sims D, Madan S, Siddiqi N, Luke A,<strong> Saeed O</strong>, Patel SR, Murthy S, Shin J, Oviedo J, Watts S, Jakobleff WA, Forest SJ, Vukelic S, Belov D, Puius Y, Minamoto G, Muggia V, Carlese A, Leung S, Rahmaniam M, Leff J, Goldstein D. Continuous-Flow Left Ventricular Asssit Device Survival Improves with Multidisciplinary Approah. The Annals of Thoracic Surgery, 2019.</p>
<p align="LEFT">4. <strong>Saeed O</strong>, Jorde U. Impact and Measurement of Blood Pressure during Continuous Flow Left Ventricular Assist Device Support: The Pressure is On! <em>ASAIO J.</em> 2019.</p>
<p align="LEFT">5. Madan S, Patel SR, <strong>Saeed O</strong>, Sims DB, Shin JJ, Goldstein DJ, Jorde UP. Outcomes of heart transplantation in patients with human immunodeficiency virus. Am J Transplant. 2019</p>
<p align="LEFT">6. <strong>Saeed O,</strong> Patel SR, Jorde UP. Bleeding and Angiogenesis during Continuous Flow Left Ventricular Assist Device (CF LVAD) support - Enter the Von Willebrand Matrix. <em>Circulation Heart Failure</em>. 2018.</p>
<p align="LEFT">7. Farooqi KM, Cooper C, Chelliah A, <strong>Saeed</strong> <strong>O</strong>, Chai PJ, Jambawalikar SR, Lipson H, Bacha EA, Einstein AJ, Jorde UP. 3D Printing and Heart failure: The Present and the Future. <em><span class="jrnl" title="JACC. Heart failure">JACC Heart Fail</span></em>. 2018 Dec 10.</p>
<p align="LEFT">8. Patel SR, Madan S, <strong>Saeed O,</strong> Sims DB, Shin JJ, Nucci C, Borukhov E, Goldstein DY, Jakobleff W, Forest S, Vukelic S, Murthy S, Reinus J, Puius Y, Goldstein DJ, Jorde UP. Cardiac transplantation from non-viremic hepatitis C donors. <em>J Heart Lung Transplant</em>. 2018.</p>
<p align="LEFT">9. Vukelic S, Vlismas P, Patel SR, Xue X, Shitole S, <strong>Saeed O</strong>, Sims DS, Chinnadurai T, Shin J, Forset S, Goldstein DJ, Jorde UP. Digoxin is Associated with Decreased Incidence of Angiodysplasia-related Gastrointestinal Bleeding in Patients with Continuous-Flow Left Ventricular Assist Devices. <em>Circulation Heart Failure</em>. 2018.</p>
<p align="LEFT">10. <strong>Saeed O</strong>, Rangasamy S, Reyes Gil M, Goldstein DJ, Billett HH, Jorde UP, Patel SR. Speed Reduction Does Not Restore High Molecular Weight Multimers of von Willebrand Factor during HeartMate II Support: An In-Vivo Study. <em>ASAIO J</em>. Sep-Oct 2018.</p>
<p align="LEFT">11. Rangasamy S, Madan S, <strong>Saeed O</strong>, Goldstein DJ, Jorde UP, Negassa A, Patel SR. Noninvasive Measures of Pulsatility and Blood Pressure During Continuous-Flow Left Ventricular Assist Device. <span class="jrnl" title="ASAIO journal (American Society for Artificial Internal Organs : 1992)"><em>ASAIO J</em></span>. 2018</p>
<p align="LEFT">12. <strong>Saeed O</strong>, Rangasamy S, Selevany I, MadanS, Fertel J, Eisenberg R, Aljoudi M, Patel SR, Shin JJ, Sims DB, Reyes Gil M, Goldstein DJ, Slepian MJ, Billett HH, Jorde UP. Sildenafil is Associated with Reduced Device Thrombosis and Ischemic Stroke Despite Low Level Hemolysis on Heart Mate II support. <em>Circulation Heart Failure</em>. 2017.</p>
<p align="LEFT">13. Patel SR, <strong>Saeed</strong> <strong>O</strong>, Naftel D, Myers S, Kirklin J, Jorde UP, Goldstein DJ. Outcomes of Restrictive and Hypertrophic cardiomyopathies after LVAD: as INTERMACS Analysis. <em><span class="jrnl" title="Journal of cardiac failure">J Card Fail</span></em>. 2017 Sep 29. pii: S1071-9164(17)31220-4.</p>
<p>14. Madan S, <strong>Saeed</strong> <strong>O</strong>, Vlismas P, Katsa I, Patel SR, Shin JJ, Jakobleff WA, Goldstein DJ, Sims DB,Jorde UP. Outcomes After Transplantation of Donor Hearts With Improving Left Ventricular Systolic Dysfunction. <span class="jrnl" title="Journal of the American College of Cardiology"><em>J Am Coll Cardiol</em></span>. 2017 Sep 5;70(10):1248-1258. </p>
<p>15. Madan S, Patel SR, Vlismas P, <strong>Saeed</strong> <strong>O</strong>, Murthy S, Forest S, Jakobleff W, Sims D, Lamour JM, Hsu DT, Shin J, Goldstein D, Jorde UP. Outcomes of Early Adolescent Donor Hearts in Adult Transplant Recipients. <span class="jrnl" title="JACC. Heart failure"><em>JACC Heart Fail</em></span>. 2017. S2213-1779(17)30320-7.</p>
<p>16. Patel SR, Oh KT, Ogriki T, Sims D, Shin JJ, Madan S, <strong>Saeed O</strong>, Goldstein DJ, Jorde UP. Cessation of Continuous Flow Left Ventricular Assist Device-Related Gastrointestinal Bleeding After Heart Transplantation. <em><span class="jrnl" title="ASAIO journal (American Society for Artificial Internal Organs : 1992)">ASAIO J</span></em>. 2017.</p>
<p>17. Madan S, Sims D, <strong>Saeed O</strong>, Patel SR, Shin JJ, Jorde UP. Association of centre volume and in-hospital mortality in heart failure hospitalisations. <em><span class="jrnl" title="Postgraduate medical journal">Postgrad Med J</span></em>. 2017.</p>
<p>18. <strong>Saeed O.</strong>, Jorde U. Advances in Continuous Flow Left Ventricular Assist Device Support for End Stage Heart Failure - A Therapy in Evolution. <em>Cardiology in Review </em>2016.</p>
<p>19. Jermyn R., Alam A., Kvasic J., <strong>Saeed O</strong>., Jorde U. Hemodynamic-guided heart-failure management using a wireless implantable sensor: Infrastructure, methods, and results in a community heart failure disease-management program. <em>Clinical Cardiology</em>. 2016 Nov.</p>
<p>20. Patel S.R., Madan S., <strong>Saeed O.,</strong> Algodi M., Luke A., Gibber M., Goldstein D.J., Jorde U.P. Association of Nasal Mucosal Vascular Alterations, Gastrointestinal Arteriovenous Malformations, and Bleeding in Patients With Continuous Flow Left Ventricular Assist Devices. <em><span class="jrnl" title="JACC. Heart failure">JACC Heart Failure</span></em>. 2016 Sep 29. pii: S2213-1779(16)30444-9.</p>
<p>21. Madan S., <strong>Saeed O.,</strong> Shin J., Sims D., Goldstein D., Pina I., Jorde U., Patel S. Donor Troponin and Survival after Cardiac Transplantation – An Analysis of the UNOS Registry. <em>Circ Heart Failure. </em>2016; Jun;9(6).</p>
<p>22. Levin A., <strong>Saeed O.,</strong> Willey, J., Levin C., Fried J., Patel S., Sims D., Nguyen J., Shin J., Topkara V., Colombo P., Goldstein DJ., Yoshifumi N., Takayama H., Uriel N, Jorde U. Watchful Waiting in CF-LVAD Patients with Ongoing Hemolysis is Associated with an Increased Risk for Cerebrovascular Accidents and Death. <em>Circ Heart Failure. </em>2016 May;9(5).</p>
<p>23. Farooqi K., <strong>Saeed O</strong>., Zaidi A., Sanz J., Nielsen J., Hsu D., Jorde U. 3D Printing to Guide Ventricular Assist Device placement in Adults with Congenital Heart Disease and Heart Failure. <em>JACC Heart Failure</em>. 2016;4: 301-11.</p>
<p>24. <strong>Saeed O.</strong>, Shah A., Kargoli F., Madan S., Levin AP., Patel SR., Jermyn R., Guerrero C., Nguyen J., Sims DB., Shin J., Goldstein D., Jorde U. Antiplatelet Therapy and Adverse Hematologic Events During Heart Mate II Support. <em>Circ Heart Failure.</em> 2016; 9 (1):e002296.</p>
<p class="Body1">25.<strong> Saeed O</strong>, Jermyn R, Kargoli F., Madan S., Mannem S, Cecilia N, Hassan S., Farooqui S, Bloom M, Mclarty A,<sup> </sup>Zolty R, Shin J, D’Alessandro D, Goldstein D, Patel S. Blood pressure and adverse events during continuous flow left ventricular assist device support.<em> Circ Heart Failure. </em>2015; 8(3):551-6.</p>
<p class="Body1">26. Habib A, Polavarapu R., Karmali V., Guo L., Van Dam R., Cheng A,. Akahori H., <strong>Saeed O.,</strong> Mastaka N., Pachura K., Hong C., Shin E., Kolodgie F., Virmani, Finn AV. The Hepcidin-Ferroportin1 Axis Controls Toll-Like Receptor 4-Dependent Macrophage Inflammatory Responses in Human Atherosclerotic Plaques. <em>Atherosclerosis</em>. 2015; 241(2) 692-700.</p>
<p>27. <strong>Saeed O.,</strong> Gupta A., Gross J, Palma E. Rate of Cardiovascular Implanted Electronic Device (CIED) re-extraction after recurrent infection. <em>Pacing and Cardiac Electrophysiology. </em>2014<em>; </em>37(8): 963-8.</p>
<p>28. Galvao M., <strong>Saeed O</strong>., Immekus J., Goldstein D., Maybaum S. An International Survey to assess Referral Thresholds for Left Ventricular Assist Device Destination Therapy in Non-Inotrope Dependent patients: Results of the Consensus DT study. <em>Journal of Cardiac Failure. </em>2014; 20(7):492-7.</p>
<p>29. <strong>Saeed O.,</strong> Maybaum S., D’Alessandro D., Goldstein D. Patel SR. Aortic Valve Opening and Thrombotic Events with Continuous Flow Left Ventricular Assist Devices. <em>J Heart Lung Transplant</em>. 2014; 33(1):109-12.</p>
<p class="Body1">30. Patel SR., <strong>Saeed O.</strong>, Murthy S., Bhatia V., Shin JJ., Wang D., Negassa A., Pullman J., Goldstein D., Maybaum S. Combining Neurohormonal Blockade with Continuous Flow Left Ventricular Assist Device (CF-LVAD) Support for Myocardial Recovery - A Single Arm Prospective Study<em>. J Heart Lung Transplant.</em> 2013; 32(3): 305-12.</p>
<p>31. <strong>Saeed O.</strong>, Bhatia V., Formica P., Browne A., Aldrich TK., Shin JJ., Maybaum S. Improved exercise performance and skeletal muscle strength after simulated altitude exposure: A novel approach for patients with chronic heart failure. <em>J Card Fail</em>. 2012; 18(5):387-91.</p>
<p>32. Finn AV, <strong>Saeed O</strong>, Virmani R. Macrophage subsets in human atherosclerosis. <em>Circulation Research. </em>2012; 110(9):e64.</p>
<p>33.<strong> Saeed O.</strong>, Otsuka F., Polavarapu R., Karmali V., Weiss D., Davis T., Rostad B., Pachura K., Adams L., Elliot J., Taylor RW., Narula J., Hong C., Kolodgie F., Virmani R., Finn AV. Pharmacologic suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis. <em>Arterioscler Thromb Vasc Biol</em><em>.</em> 2012; 32: 299-307.</p>
<p>34. Finn AV., Nakano M., Polavarapu R., Karmali V., <strong>Saeed O.</strong>,Zhao X., Yazdani S., Davis T., Habib A., Narula J., Kolodgie F, Virmani R. Hemoglobin directs macrophage differentiation and determines lipid uptake human atherosclerotic plaques. <em>J Am Coll Cardiol</em>. 2012; 59(2): 166-177.</p>
<p>35. Wei C., Li L., Torben B., <strong>Saeed O.</strong>, Thabet S., Jansen T., Dikalov S., Weyand C.,Goronzy J., Harrison DG. The role of increased GTP cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation. <em>J Biol Chem. </em>2011; 286(16): 13846-51. </p>
<p>36.<strong> Saeed O</strong>., Yaghmaie F., Garan SA., Gouw A., Voelker M., Freitag W., Sternberg H., Timiras PS. Insulin like Growth Factor -1 immunoreactive cells are selectively maintained in the paraventricular hypothalamus of calorically restricted mice <em>Intl. J.</em> <em>Dev. Neuroscience. </em>2007; 25(1):23-8.</p>
<p>37. Yaghmaie F., <strong>Saeed O.</strong>,Garan S.A., Gouw A., Voelker M., Freitag W., Sternberg H., Timiras PS. Age dependent loss of Insulin like Growth Factor -1 immunoreactive cells in the supraoptic hypothalamus is reduced in calorically restricted mice. <em>Intl. J. Dev. Neuroscience. </em>2006; 24(7):431-6.</p>
<p>Omar Saeed, MD, is an Attending Cardiologist at Montefiore and Assistant Professor of Medicine at our Albert Einstein College of Medicine. His clinical focus is on heart failure, heart transplantation and mechanical circulatory support.</p><p>After receiving his Bachelor of Arts in molecular and cellular biology from the University of California, Berkeley in 2003, Dr. Saeed attended New York Medical College, earning his Doctor of Medicine in 2007. He began his postdoctoral training at Emory University Hospital, completing a residency in internal medicine in 2010 and a fellowship in cardiovascular disease in 2011. He then transferred to Albert Einstein College of Medicine. Here he completed a research fellowship in heart failure, transplant and mechanical circulatory support in 2012, a cardiovascular disease fellowship in 2014 and a fourth-year clinical fellowship in advanced heart failure and transplant in 2015.</p><p>Dr. Saeed’s research focuses on the mechanisms of hematological and neurological adverse events during mechanical circulatory support. He has published as primary author or as co-author over 50 peer-reviewed manuscripts, and he has presented regionally, nationally and internationally. He also has been an invited manuscript reviewer for many journals, including <em>Haemostasis and Thrombosis, </em>the <em>Journal of Lung and Heart Transplantation</em> and the <em>Journal of Human Immunology</em>.</p><p>Dr. Saeed has received the Martin Cohen award for excellence in cardiovascular fellowship training, the Edmund Sonnenblick award for excellence in heart failure research and the NIH K23 career development award supporting his commitment to patient-oriented research. He is board certified and is a member of several professional organizations, including the American College of Cardiology, the American Society of Echocardiography and the International Society of Heart and Lung Transplant.</p>
Yogita M. Rochlani
Dr. Rochlani's clinical areas of focus include cardiac sarcoidosis, myocarditis, cardiac transplantation, and mechanical circulatory support.<quillbot-extension-portal></quillbot-extension-portal>
Dr. Rochlani's research interests include inflammatory cardiomyopathies, particularly cardiac sarcoidosis, donor selection for transplantation, and factors that impact post-transplant longevity, particularly cardiac allograft vasculopathy. She serves as a principal investigator for a study evaluating the phenotypic profiles and natural history of cardiac sarcoidosis, and as the site principal investigator for the Cardiac Sarcoidosis Multicenter Randomized Controlled Trial evaluating immunosuppressive treatment strategies for the treatment of cardiac sarcoidosis.<quillbot-extension-portal></quillbot-extension-portal>
Snehal R. Patel
<p>Clinical areas of expertise include heart failure, cardiac transplantation, mechanical circulatory support.</p>
Sandhya Murthy
Shivank A. Madan
Ulrich P. Jorde
<p>Dr. Ulrich Jorde’s laboratory is focused on translational research in advanced heart failure including heart replacement therapy; i.e. durable mechanical circulatory support (left ventricular assist devices/ “artificial hearts”) or cardiac transplantation.</p>
<p>The basis for Dr. Jorde's work is a large clinical program with approximately 2000 heart failure admissions, 35 adult cardiac transplants, and 50 left ventricular assist devices annually. All work is done in close collaboration with cardiothoracic surgical colleagues.</p>
<p>Representative examples of Dr. Jorde’s research include:</p>
<ol>
<li>Investigator initiated mechanistic studies:
<ul type="disc">
<li>Studies of the nasal mucosa vasculature in “pulseless” heart failure patients on continuous-flow LVADs</li>
<li>Hemolysis patterns in CF-LVAD patients and their association with device thrombosis (collaboration with Henny Billett, MD – Hematology)</li>
<li>Reversal of heart failure induced diabetes in CF-LVAD patients</li>
</ul>
</li>
<li>Basic Science Collaborations – Myocardial recovery during mechanical circulatory support (collaboration with Nicholas Frangogiannis, MD)</li>
<li>Outcomes/epidemiology studies – Effect of center volume on survival during heart failure hospital admission</li>
<li>Multicenter studies of investigational mechanical circulatory support devices:
<ul type="disc">
<li>MOMENTUM Trial: A 1200-patient study of long term durable support as bridge to transplantation or destination therapy with the HM III (national PI: Daniel Goldstein, MD)</li>
<li>SHIELD 2: A 452 patient study of acute mechanical circulatory support with the Percutaneous Heart Pump. (national PI: Ulrich Jorde, MD)</li>
</ul>
</li>
</ol>
Specialization in heart failure, cardiac transplantation and mechanical circulatory support for left ventricular assist devices (LVAD); and cardiogenic shock
<ol>
<li>Uriel N, Naka Y, Colombo PC, Farr M, Pak SW, Cotarlan V, Albu JB, Gallagher D, Mancini D, Ginsberg HN, Jorde UP. Improved diabetic control in advanced heart failure patients treated with left ventricular assist devices. Eur J Heart Fail. 2011 Feb;13(2):195-9. </li>
<li>Hirsh B, Mignatti A, Sims DB, Uriel N, Colombo PC, Jorde UP. Effect of beta Blocker Cessation on Chronotropic Incompetence and Exercise Tolerance in Patients with Advanced Heart Failure. Circ Heart Fail. 2012 Sep 1;5(5):560-5.</li>
<li>Uriel N, Morrison K, Garan AR, Kato T, Yuzefpolskaya M, latif F, Restaino S, Mancini DM, Flannery M, Takayama H, John R, Colombo PC, Naka Y, Jorde UP. Development of a novel echocardiography ramp test for speed optimization and diagnosis of device thrombosis in continuous flow left ventricular assist devices: The Columbia Ramp Study. J Am Coll Cardiol. 2012 Oct 30;60(18):1764-75.</li>
<li>Uriel N, Gonzalez-Costello J, Mignatti A, Morrison K, Colombo PC, Jorde UP. Adrenergic Activation Governs Fuel Substrate Availability and Insulin Resistance in Patients with Congestive Heart Failure. J JACC: Heart Failure Vol. 1, Issue 4, Pages 331-337. </li>
<li>Jorde UP , Khushwaha SS, Tatooles AJ, Naka Y, Bhat G, Long JW, Horstmanshof D, Kormos RL, Teuteberg JJ, Slaughter MS, Birks EJ, Farrar DJ, Park SJ. Two-Year Outcomes in the Destination Therapy Post-FDA-Approval Study with a Continuous Flow Left Ventricular Assist Device: A Prospective Study Using the INTERMACS Registry. J Am Coll Cardiol. 2014 May 6;63(17):1751-7. </li>
<li>Jorde UP, Uriel N, Nahumi N, Bejar D, Gonzalez-Costello J, Thomas SS, Han J, Morrison KA, Jones S, Kodali S, Hahn RT, Shames S, Colombo PC, Takayama H, Naka Y. Prevalence, significance, and management of aortic insufficiency in continuous flow left ventricular assist device recipients. Circ HF; Circ Heart Fail. 2014 Mar 1;7(2):310-9.</li>
</ol>