COURSE DESCRIPTION:
The course will consider both innate and adaptive immunity and include the structure and function of key receptors including innate Pattern Recognition Receptors, Major Histocompatibility Complex, Immunoglobulins and T Cell Receptors. The mechanisms of innate immune responses, antibody formation and molecular aspects of cellular immunity, including T and B cell interactions and memory lymphocyte formation, will be emphasized, and connections to modern biomedical science will be highlighted. These will include presentations and discussions on autoimmunity, immunity against microbial pathogens, transplantation, and tumor immunology. The course will rely on multiple materials, including formal lectures (by sixteen Einstein faculty), seminal paper discussions, immunological methods and mouse model lectures, assigned reading (selected textbook chapters and cutting-edge review articles), didactic videos, and data-driven learning sessions (“hands-on” data analysis and interpretation).

COURSE OBJECTIVES:
The goal of the course is to provide students with a broad overview of basic immunology, while also delving deeply into cellular and molecular details in areas of central importance to the field. Successful completion of the course will provide students with strong fundamental knowledge in basic immunology, and assist them in deepening their knowledge of current research and developments in modern immunology.

PREREQUISITES:
Although there are no formal prerequisites, students who are completely new to immunology are especially advised to do some preparation in advance to become familiar with the basics.

REQUIRED MATERIALS:
Textbook: Janeway's Immunobiology 10th edition, Murphy, Weaver, and Berg, ISBN-13: 978-0393884906, ISBN-10: 0393884902 Computer access; internet access

SUITABLE FOR 1ST YEAR STUDENTS:
Yes

STUDENT ASSESSMENTS:

First-quarter exam	15 points
Participation	10 points
Midterm exam	30 points
Final exam	45 points
	100 points

Students earning a total of 70 points or greater will receive a passing grade for the course. Lower point totals may also qualify as passing, but this will need to be determined once the grade distribution has been evaluated.

The participation grade will be determined based on attendance and contributions to class discussions, including seminal paper and data sessions.

CREDIT HOURS: 4.0