Dr Campbell is a cancer epidemiologist focused on identifying lifestyle, behavioral, clinical, and biological risk and prognostic factors for cancers diagnosed in the gastrointestinal tract, particularly the colorectum and liver. Much of his work integrates aspects of pathology, molecular biology, genetics, and clinical medicine into epidemiology studies. His research involves consortia of study data and biologic specimens from hundreds of thousands of study participants, utilizes leading ‘omics and high-throughput technologies, and employs novel statistical techniques.

Dr Campbell also examines the role of behavioral factors on survival after a cancer diagnosis. The overarching goal of this research is to better understand how and why some lifestyle/behavioral factors influence cancer prognosis with a view to better inform and support the care of cancer patients.

Additionally, Dr Campbell is PI of the newly formed Colorectal Cancer Pooling Project (‘C2P2’) which aims to better understand the risk factors for early-onset colorectal cancer by combining data and study resources from >3.7 million study participants, among whom >53,000 persons have been diagnosed with colon or rectal cancers.

(selected from over 200)        

M.A. Guinter, M.L. McCullough, S.M. Gapstur, P.T. Campbell. Associations of pre- and post-diagnosis diet quality with risk of mortality among men and women with colorectal cancer. Journal of Clinical Oncology, JCO1800714, 2018. PMID: 30339519.

J.L. Petrick, P.L. Hyland, P. Caron, R.T. Falk, R.M. Pfeiffer, S.M. Dawsey, C.C. Abnet, P.R.Taylor, S.J. Weinstein, D. Albanes, N.D. Freedman, S.M. Gapstur, G. Bradwin, C. Guillemette, P.T. Campbell, M.B. Cook. Associations between prediagnostic concentrations of circulating sex steroid hormones and esophageal/gastric cardia adenocarcinoma among men. Journal of the National Cancer Institute, 111 (1): 34-41, 2019. PMID: 29788475. 

J.R. Huyghe, S.A. Bien, T.A. Harrison, (33 others), P.T. Campbell, (more than 140 others), S.B. Gruber, L. Hsu, U. Peters. Discovery of common and rare genetic risk variants for colorectal cancer. Nature Genetics, 51 (1): 76-87, 2019. PMID: 30510241.

M.B. Cook, M.J. Barnett, C.H. Bock, A.J. Cross, P.J. Goodman, G.E. Goodman, C.A. Haiman, K.T. Khaw, M.L. McCullough, C.C. Newton, M.C. Boutron-Ruault, E. Lund, M. Rutegård, M.D. Thornquist, M. Spriggs, C. Giffen, N.D. Freedman, T. Kemp, C.H. Kroenke, L. Le Marchand, J.Y. Park, M. Simon, L.R. Wilkens, L. Pinto, A. Hildesheim, P.T. Campbell. Pre-diagnostic circulating markers of inflammation and risk of oesophageal adenocarcinoma: a study within the National Cancer Institute Cohort Consortium. Gut, 68 (6): 960-968, 2019. PMID: 30121626. 

S.S. Jackson, A.L. Van Dyke, B. Zhu, (54 others), K.A. McGlynn, P.T. Campbell, J. Koshiol. Anthropometric risk factors for cancers of the biliary tract in the Biliary Tract Cancers Pooling Project. Cancer Research, 79 (15): 3973-3982, 2019. PMID: 31113819.

P.T. Campbell, C.B. Ambrosone, R. Nishihara, H.J.W.L. Aerts, M. Bondy, N. Chatterjee, M. Garcia-Closas, M. Giannakis, J.A. Golden, Y.J. Heng, N.S. Kip, J. Koshiol, X.S. Liu, C.M. Lopes-Ramos, L.A. Mucci, J.A. Nowak, A.I. Phipps, J. Quackenbush, R.E. Schoen, L.M. Sholl, R.M. Tamimi, M. Wang, M.P. Weijenberg, C.J. Wu, K. Wu, S. Yao, K.H. Yu, X. Zhang, T.R. Rebbeck, S. Ogino. Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting. Cancer Causes and Control, 30 (8): 799-811, 2019. PMID: 31069578.

E.E. McGee, S.S. Jackson, J.L. Petrick, (50 others), K.A. McGlynn, P.T. Campbell, J. Koshiol. Smoking, alcohol, and biliary tract cancer risk: a pooling project of 26 prospective studies. Journal of the National Cancer Institute, 111 (12): 1263-1278, 2019. PMID: 31127946.

M.A. Guinter, S.M. Gapstur, M.L. McCullough, W.D. Flanders, Y. Wang, E. Rees-Punia, K.I. Alcaraz, M.N. Pollak, P.T. Campbell. Prospective association of energy balance scores based on metabolic biomarkers with colorectal cancer risk. Cancer Epidemiology Biomarkers & Prevention, 29 (5): 974-981, 2020. PMID: 32094199.

S.H. Zaidi, T.A. Harrison, A.I. Phipps, (68 others), P.T. Campbell, S.N. Thibodeau, W. Sun, T.J. Hudson, U. Peters. Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival. Nature Communications, 11 (1): 3644, 2020. PMID: 32686686.

A. Hidaka, T.A. Harrison, Y. Cao, (36 others), D.D. Buchanan, P.T. Campbell, U. Peters. Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies. Cancer Research, 80 (20): 4578-4590, 2020. PMID: 32816852.

P.T. Campbell, Y. Lin, S.A. Bien, J.C. Figueiredo, T.A. Harrison, M.A. Guinter, S.I. Berndt, H. Brenner, A.T. Chan, J. Chang-Claude, S.J. Gallinger, S.M. Gapstur, G.G. Giles, E. Giovannucci, S.B. Gruber, M. Gunter, M. Hoffmeister, E.J. Jacobs, M.A. Jenkins, L. Le Marchand, L. Li, J.R. McLaughlin, N. Murphy, R.L. Milne, P.A. Newcomb, C. Newton, S. Ogino, J.D. Potter, G. Rennert, H.S. Rennert, J. Robinson, L.C. Sakoda, M.L. Slattery, Y. Song, E. White, M.O. Woods, G. Casey, L. Hsu, U. Peters. Association of body mass index with colorectal cancer risk by genome-wide variants. Journal of the National Cancer Institute, 113 (1): 38-47, 2021. PMID: 32324875.

J.C. Figueiredo, E.J. Jacobs, C.C. Newton, M.A. Guinter, W.G. Cance, P.T. Campbell. Associations of aspirin and non-aspirin non-steroidal anti-inflammatory drugs with colorectal cancer mortality after diagnosis. Journal of the National Cancer Institute, 113 (7): 833-840, 2021. PMID: 33528005.