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Julio A. Aguirre-Ghiso, Ph.D.

Julio A. Aguirre-Ghiso, Ph.D.

Professor, Cell Biology, Medicine and Oncology

Founding director, Cancer Dormancy and Tumor Microenvironment Institute

Co-Director, Gruss-Lipper Biophotonics Center

Co-Leader, Montefiore Einstein Comprehensive Cancer Center Tumor Microenvironment and Metastasis Program

Cancer biologyCancer dormancy and the tumor microenvironmentCancer metastasisStress signaling

Julio Aguirre-Ghiso, Ph.D., is an international leader in cancer cell dormancy and metastasis. He has helped lead a major shift in the cancer biology field by investigating how cancer cells hibernate, undetected, for long periods of time and what causes them to suddenly awaken to seed deadly, treatment-resistant metastases. read more...

 

Nir Barzilai, M.D.

Nir Barzilai, M.D.

Professor, Medicine (Endocrinology)

Director, Institute for Aging Research

Director, Nathan Shock Center of Excellence in the Basic Biology of Aging

Ingeborg and Ira Leon Rennert Chair of Aging Research

AgingBiology of agingLongevity genes

Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity. Dr. Barzilai has been profiled by major outlets, including The New York Times, PBS’ “NOVA scienceNow” and National Geographic. read more...

 

Aviv Bergman, Ph.D.

Aviv Bergman, Ph.D.

Professor and Founding Chair, Systems & Computational Biology

Professor, Pathology

Professor, Dominick P. Purpura Department of Neuroscience

Harold and Muriel Block Chair in Systems & Computational Biology

Evolutionary biologySystems biologyBiological modeling

 Dr. Bergman combines data from basic and clinical research to create computer models of complex biological systems. As these models evolve, his work could contribute to calculating individualized medical outcomes and guiding treatment for patients based on their personal genetic make-up. Dr. Bergman has teamed with colleagues to study a variety of complex conditions, including aging, cancer and neurodegenerative diseases. read more...

 

Craig A. Branch, Ph.D.

Craig A. Branch, Ph.D.

Associate Professor, Radiology

Director, Gruss Magnetic Resonance Research Center

Co-Director, EGL Integrated Imaging Program

Magnetic resonance imaging (MRI)Sickle cell disease Traumatic Brain Injury and Concussion MRI measures of function and physiology

Dr. Craig Branch is an internationally-known MRI researcher who has been a pioneer in using the technology since it was first developed in the early 1980s. Dr. Branch directs Einstein’s Gruss Magnetic Resonance Research Center, which supports a wide variety of MRI studies of brain injury and disease, liver disease, cancer, and other disorders. 

Dr. Branch specializes in the use of MRI to study disease in both humans and animal models. He was one of the first to use MRI to measure blood flow in the brain, and he employs the technology to assess brain function and structure in numerous disorders, including sickle cell disease, stroke, traumatic brain injury and schizophrenia. He is one of the only researchers to have used animal models of sickle cell disease (SCD) to research the biological mechanisms that underlie cognitive impairment and strokes in SCD. Research findings in this area suggest that brain blood flow associated with SCD strokes is unusually high—a finding that could lead to treatments that might ward off strokes in SCD patients.  

Dr. Branch is also Co-Director of the Evelyn-Gruss-Lipper Integrated Imaging Program (EGL-IIP) which seeks to use microscopic-to-macroscopic imaging scales to understand the mechanisms that contribute to breast and other metastatic cancers.  Research in this area incorporates both rodent models of cancer and clinical studies of human breast cancer. In addition to his NIH-funded research, Dr. Branch has served as an MRI expert on several NIH ad-hoc review committees.
 

John S. Condeelis, Ph.D.

John S. Condeelis, Ph.D.

Professor, Cell Biology

The Judith and Burton P. Resnick Chair in Translational Research

Chair Emeritus Department of Anatomy & Structural Biology

Co-Director, Integrated Imaging Program

Scientific Director, Analytical Imaging Facility

Director, Integrated Imaging Program for Cancer Research

Biomedical technologiesIntravital imagingTumor microenvironmentBreast cancerMetastasis

Dr. Condeelis is a pioneer in developing microscope techniques for use in “intravital imaging” – observing the behavior of cells in living animals. His work has led to a clinical test of biopsy tissue to determine whether a woman’s breast cancer will spread (metastasize), which could help determine treatment. Because of the test’s success, Dr. Condeelis and colleagues have licensed the patent rights to a biotech firm, which is developing the tissue test into a commercial product. read more...

 

Jill P. Crandall, M.D.

Jill P. Crandall, M.D.

Professor, Department of Medicine (Endocrinology)

Jacob A. and Jeanne E. Barkey Chair in Medicine

Chief, Division of Endocrinology

Director, Fleischer Institute for Diabetes and Metabolism

DiabetesType 2 diabetesDiabetes prevention

Clinical TrialsPrediabetesResveratrol

An expert in diabetes prevention, Dr. Crandall is director of the Diabetes Clinical Trials Unit at Einstein and Montefiore and a principal investigator for several NIH-sponsored clinical trials, including the Diabetes Prevention Program Outcome Study (for which she holds several national leadership positions, including Executive Committee membership), Glycemia Reduction Approaches in Diabetes (GRADE) and the PERL (Preventing Early Renal Loss) study.  read more...

 

Ana Maria Cuervo, Ph.D., M.D.

Ana Maria Cuervo, Ph.D., M.D.

Professor, Developmental and Molecular Biology

Professor, Anatomy and Structural Biology

Co-Director, Institute for Aging Research

Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases

Molecular BiologyAgingAutophagy

Cellular biology

Dr. Cuervo is considered a leader in the field of autophagy— the process by which cells remove and recycle their waste. The Barcelona, Spain native is also an expert on the cellular biology of aging. Dr. Cuervo has been quoted in numerous publications, including The New York Times, Nature, Science, Scientific American, and The Scientistread more...

 

Vilma Gabbay, M.D.

Vilma Gabbay, M.D.

Professor, Psychiatry and Behavioral Sciences

Professor, Dominick P. Purpura Department of Neuroscience

Co-Director, Psychiatry Research Institute of Montefiore and Einstein (PRIME)

Director, Pediatric Mood and Anxiety Disorders Research Program, Einstein and Montefiore Health System

Pediatric anxiety & mood disordersAdolescent depression & suicideBiology of depression/neuroinflammationCOVID-19 & psychosis

Vilma Gabbay, Ph.D., is one of the nation’s leading experts on pediatric mood and anxiety disorders. She has received numerous federal grants to study a range of subjects, including neuroinflammation, teenage anhedonia (inability to feel pleasure), and brain systems related to reward-seeking behaviors in adolescent suicide and depression. read more...

 

Mario J. Garcia, M.D.

Mario J. Garcia, M.D.

Co-Director, Montefiore Einstein Center for Heart and Vascular Care

Chief, Cardiology, Department of Medicine, Einstein and Montefiore Health System

Professor, Medicine (Cardiology), Einstein

Pauline A. Levitt Chair in Medicine, Einstein

Heart DiseaseCardiologyCardiac imaging

Cardiovascular disease

Vilma Gabbay, Ph.D., is one of the nation’s leading experts on pediatric mood and anxiety disorders. She has received numerous federal grants to study a range of subjects, including neuroinflammation, teenage anhedonia (inability to feel pleasure), and brain systems related to reward-seeking behaviors in adolescent suicide and depression. read more...

 

Charles B. Hall, Ph.D.

Charles B. Hall, Ph.D.

Professor, Epidemiology & Population Health

Professor, Saul R. Korey Department of Neurology

Alzheimer's disease/dementiaAgingCognition

EpidemiologyBiostatistics

Dr. Hall is a biostatistician recognized for leading important long-term studies of aging and dementia. His research has shown, for example, that brain-stimulating activities delay the onset of dementia. He is the longtime director of the statistical core of the Einstein Aging Study, one of the longest-running prospective studies of aging in the country. He is also the lead statistician for the data coordinating center of the federally funded World Trade Center (WTC) Medical Monitoring & Treatment Program, which provides free health monitoring and treatment for workers and volunteers involved in the rescue, recovery and clean-up activities at the WTC site in New York City. read more...

 

Richard B. Lipton, M.D.

Richard B. Lipton, M.D.

Vice Chair and Professor, Saul R. Korey Department of Neurology, Einstein

Director, Montefiore Headache Center

Director, Einstein Aging Study, Einstein

Edwin S. Lowe Chair in Neurology, Einstein

HeadacheAgingAlzheimer's disease/dementia

MigraineCognitive aging

A noted authority on headaches and migraine, Dr. Lipton is director of the Montefiore Headache Center, recognized internationally for its leadership in the diagnosis, classification and treatment of headache disorders. Dr. Lipton is also director of the Einstein Aging Study, which has been examining both normal brain aging and the special challenges of Alzheimer’s disease and other dementias since 1980.  read more...

 

Sophie Molholm, Ph.D.

Sophie Molholm, Ph.D.

Professor, Pediatrics

Professor, Dominick P. Purpura Department of Neuroscience

Professor, Psychiatry and Behavioral Sciences

Director, Sheryl and Daniel R. Tishman Cognitive Neurophysiology Laboratory

Co-Director, Rose F. Kennedy Intellectual & Developmental Disabilities Research Center (IDDRC)

AutismBrain imaging (Electrophysiology and fMRI)Sensory processingMultisensory integrationExecutive functionPredictive processing

Dr. Molholm is a leader in the field of multisensory integration and focuses her research on developmental disorders, with an emphasis on autism, and on rare genetic conditions. She studies how the human brain processes and integrates sensory inputs—sight, sound, and touch—to impact perception and behavior. She also studies higher order processes such as attention and executive function, and how these interact with lower order cortical processes. Using non-invasive techniques, including brainwave electroencephalogram (EEG) recordings and magnetic resonance imaging (MRI), Dr. Molholm examines the link between deficits in information processing and autism, and how these relate to different neurodevelopmental and neuropsychiatric conditions. read more...

 

Jeffrey E. Segall, Ph.D.

Jeffrey E. Segall, Ph.D.

Professor, Anatomy and Structural Biology

Professor, Pathology

Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research

Biomedical technologiesImagingTumor cell imaging

Dr. Segall studies how tumor cells invade tissues and spread through the body. He has developed sophisticated imaging methods for following individual tumor cells moving in living animals. For example, one of his techniques involves a tiny glass window implanted in the skin of a mouse that allows scientists to track individual cancer cells as they spread a tumor site and attack other parts of the body. This technique could one day be used for assessing the effectiveness of specific drugs in preventing cancer from metastasizing. read more...

 

Robert H. Singer, Ph.D.

Robert H. Singer, Ph.D.

Professor and Co-chair, Anatomy & Structural Biology

Co-director, Gruss Lipper Biophotonics Center

Professor, Dominick P. Purpura Department of Neuroscience

Professor, Cell Biology

Harold and Muriel Block Chair in Anatomy & Structural Biology

Single-cell imagingmRNABiophotonics

Dr. Singer is a leader in the field of biophotonics, which enables scientists to observe activities within living cells at the molecular level, and in the study of mRNA, a molecule that controls the expression and positioning of proteins within cells. Dr. Singer, who was called a “pioneer” by Science magazine, leads a robust lab that focuses on how RNA is expressed by the genome and how it travels from the site of its birth to its ultimate location in the cell where it makes proteins. read more...

 

Joanna L. Starrels, M.D., M.S.

Joanna L. Starrels, M.D., M.S.

Associate Professor, Medicine (General Internal Medicine)

Attending Physician, General Internal Medicine, Montefiore Health System

Prescription opioid use in chronic painPrescription drug abuseOpioid prescription guidelinesOpioids and HIV

Dr. Starrels is a physician, teacher and researcher who focuses on the safety and effectiveness of opioids for the management of chronic pain. Her research centers on defining best practices for managing chronic pain in primary care and HIV-treatment settings. She studies the benefits and harms of using treatment agreements, urine drug testing, and prescription monitoring programs in pain management; the effectiveness of collaborative care models for integrating behavioral health care and pain management; treatment of opioid use disorders in primary care settings; and the impact of opioid analgesic use, misuse and disorders on HIV outcomes.  read more...

 

Joe Verghese, M.B.,B.S., M.S.

Joe Verghese, M.B.,B.S., M.S.

Professor, Saul R. Korey Department of Neurology, Einstein

Murray D. Gross Memorial Faculty Scholar in Gerontology, Einstein

Chief, Divisions of Cognitive and Motor Aging, Einstein and Montefiore

Attending Physician, Department of Neurology, Montefiore Health System

Chief, Division of Geriatrics, Montefiore Health System

Alzheimer's disease/dementiaGait/mobilityAgingFallsFrailty

Dr. Joe Verghese is a board-certified neurologist and expert on aging who assesses how diseases and aging affect cognitive ability and mobility in older adults. Among his current projects, he is evaluating the effectiveness of a non-invasive brain stimulation technique intended to alleviate symptoms of Alzheimer’s disease and improve brain function. He is also conducting studies across the world to identify the causes of cognitive impairment and risk factors for Alzheimer’s disease and dementia. read more...

 

Jan Vijg, Ph.D.

Jan Vijg, Ph.D.

Professor and Chair, Genetics

Professor, Ophthalmology and Visual Sciences

Lola and Saul Kramer Chair in Molecular Genetics

GeneticsGenomic instabilityAging

Cancer

Dr. Vijg studies the molecular genetic changes associated with aging. Instability of genome and epigenome – the entire set of an organism’s genes and the switches that control their activity –  has long been implicated as the main cause of cancer and of the loss of organ and tissue function associated with aging. read more...