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Yingjie Zhao, Ph.D.
Email: yingjie.zhao@einsteinmed.org
Education:
B.S., Biologi, Lanzhou University, Gansu Province, China
Ph.D., Genetics, School of Life
Sciences, Fudan
University, Shanghai, China
Research interest:
Yingjie’s
work focuses on the etiology and heterogeneity of cardiac congenital heart
defects among 22q22.1 deletion syndrome populations. She has great interests on
large-scale data analysis and mining including genome wide association study,
whole exome sequencing and whole genome sequencing.
Previous publications:
- Zhao Y*, Chen G*, Zhao
Y, Song X, Chen H, Mao Y and Lu D. Fine-mapping of a region of chromosome
5p15.33 (TERT-CLPTM1L) suggests a
novel locus in TERT and a CLPTM1L haplotype are associated with glioma
susceptibility in a Chinese population. International Journal of Cancer.
2012; 131(7):1569-1576.
- Zhao Y*, Chen G*, Yu
H, Hu L, Bian Y, Yun D, Chen J, Chen H, Mao Y, Lu D. Development of Risk
Prediction Models for Glioma Based on Genome-Wide Association Study Findings
and Comprehensive Evaluation of Predictive Performances. Oncotarget. 2016; Epub
ahead of print.
- Zhao Y*, Yun D*, Zou X, Jiang T, Li G, Yun D, Chen G, Hu L, Bian
Y, Chen J, Xu J, Mao Y, Chen H and Lu D. Whole Exome-Wide Association Study
Identifies a Missense Variant in SLC2A4RG Associated with Glioblastoma Risk. American
Journal of Cancer Research. Accepted
- Zhao Y, Zou X, Jiang
T, Li G, Yun D, Chen G, Hu L, Bian Y, Chen J, Xu J, Mao Y, Chen H and Lu D.
Whole-exome array analysis of glioblastoma susceptibility in a Chinese
population. Submitted to Carcinogeneises,
Under review
- Zhao Y, Yun D, Zou X, Chen
G, Bian Y, Yun D, Hu L, Bian Y, Genome wide survival analysis of glioblastoma.
In drafting
- Song X, Zhou K, Zhao Y, Huai
C, Zhao Y, Yu H, Chen Y, Chen G, Chen H, Fan W, Mao Y and Lu D. Fine mapping
analysis of a region of 20q13.33 identified five independent susceptibility
loci for glioma in a Chinese Han population. Carcinogenesis. 2012;
33(5):1065-1071.
- Fan S*, Zhao Y*, Li X, Du Y,
Wang J, Song X, Zhou F, Chen H, Chen G, Zhao Y, Mao Y and Lan Q. Genetic
variants in SLC7A7 are associated with risk of glioma in a Chinese population. Experimental
biology and medicine. 2013; 238(9):1075-1081.
- Wu Y, Yun D, Zhao Y, Wang Y, Sun
R, Yan Q, Zhang S, Lu M, Zhang Z, Lu D. Down regulation of RNA binding motif,
single-stranded interacting protein 3, along with up regulation of nuclear
HIF1A correlates with poor prognosis in patients with gastric cancer. Oncotarget. 2016;
Accepted
- Chen H, Sun B, Zhao Y, Song
X, Fan W, Zhou K, Zhou L, Mao Y and Lu D. Fine mapping of a region of
chromosome 11q23.3 reveals independent locus associated with risk of glioma. PloS
one. 2012; 7(12): e52864.
- Meng D, Chen Y, Zhao Y, Wang
J, Yun D, Yang S, Chen J, Chen H and Lu D. Expression and prognostic
significance of TCTN1 in human glioblastoma. Journal of translational medicine. 2014; 12:288.
- Hu D, Zhang S, Zhao Y, Wang
S, Wang Q, Song X, Lu D, Mao Y and Chen H. Association of genetic variants in
the retinoblastoma binding protein 6 gene with the risk of glioma: a
case-control study in a Chinese Han population. Journal of neurosurgery.
2014; 121(5):1209-1218.
- Fan W, Zhou K, Zhao Y, Wu W,
Chen H, Jin L, Chen G, Shi J, Wei Q, Zhang T, Du G, Mao Y, Lu D and Zhou L.
Possible association between genetic variants in the H2AFX promoter region and
risk of adult glioma in a Chinese Han population. Journal of neuro-oncology.
2011; 105(2):211-218.
- Chen H, Wang W, Zhao Y, Song
X, Fan W, Zhou K, Chen G, Zhao Y, Mao Y and Lu D. Association between genetic
variations of vascular endothelial growth factor receptor 2 and glioma in the
Chinese Han population. J Mol Neurosci. 2012; 47(3):448-57.
- Meng D, Chen Y, Yun D, Zhao Y,
Wang J, Xu T, Li X, Wang Y, Yuan L, Sun R, Song X, Huai C, Hu L, Yang S, Min T,
Chen J, et al. High expression of N-myc (and STAT) interactor predicts poor
prognosis and promotes tumor growth in human glioblastoma. Oncotarget. 2015;
6(7):4901-4919.
- Li X, Qu L, Zhong Y, Zhao Y,
Chen H and Lu D. Association between promoter polymorphisms of matrix
metalloproteinases and risk of digestive cancers: a meta-analysis. J
Cancer Res Clin Oncol. 2013;139(9):1433-47.
- Fan W, Zhou K, Hu D, Song X, Zhao
Y, Chen H, Wei Q, Chen G, Shi J, Du G, Mao Y, Lu D and Zhou L. Single
nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a
Chinese Han population. Molecular carcinogenesis. 2012; 51
Suppl 1: E1-10.
- Chen Y, Meng D, Wang H, Sun R, Wang D, Wang S, Fan J, Zhao Y, Wang J, Yang S, Huai C, Song X,
Qin R, Xu T, Yun D, Hu L, et al. VAMP8 facilitates cellular proliferation and
temozolomide resistance in human glioma cells. Neuro-oncology. 2015;
17(3):407-418.
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