Overview Aging has a biology, and this biology drives age-related diseases (Geroscience). We at Einstein have demonstrated that the biology of aging can be targeted in experimental models to delay, stop, and in some examples, reverse manifestations of aging. Our overarching Mission is to make scientific discoveries in geroscience, leveraging on the expertise in our center in studying and targeting the pillars of aging, and to confirm their relevance of new findings to human aging through the unique Gero-human resource created in our center and to translate interventions proven relevant for human to drug discovery efforts. Centers of Excellence The institute for Aging Research is the home of two aging centers of international recognition. The Nathan Shock Center of Excellence, focused on the study of the biology of aging and the Einstein Paul F. Glenn Center solely dedicate to understanding the biology behind human Aging. Learn More Nathan Shock Center of Excellence LEARN MORE The Paul F. Glenn Center for Biology of Human Aging LEARN MORE Research Integrative Physiology Dietary strategies to delay aging Metabolism targeting to delay aging Cell autonomous and non-autonomous aging CNS control of metabolism and aging Cell Biology of Aging Proteostasis DNA repair Response to Stress Inflammaging Stem Cells Genetics of Aging Human Longevity Comparative genomics of longevity Translational Geroscience TAME Human Longevity Studies Clinical Geriatrics Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Multimedia 2nd Annual Longevity Studies Symposium More Videos Highlights News Release Einstein Aging Study Receives $32 Million Grant to Study Alzheimer’s Disease Apr 20, 2022 News Release Einstein Researchers Find New Strategy for Preventing Clogged Arteries Mar 28, 2022 News Release Promising Approach Against Treatment-Resistant Cancer Mar 07, 2022 See All Publications See More Misfolded GBA/β-glucocerebrosidase impairs ER-quality control by chaperone-mediated autophagy in Parkinson diseaseThe immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity developmentResilience to aging is a heterogeneous characteristic defined by physical stressorsQuality Control: Maintaining molecular order and preventing cellular chaosHeterochronic parabiosis: a valuable tool to investigate cellular senescence and other hallmarks of agingMicroglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathySingle-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smokingSingle-molecule, quantitative detection of low-abundance somatic mutations by high-throughput sequencingProtective role of chaperone-mediated autophagy against atherosclerosisGeroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization