Past Events | Dominick P. Purpura Department of Neuroscience | Dominick P. Purpura Department of Neuroscience

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25 May May

Works in Progress: TBD, Maria Agustina Frechou

Thu May 25 2017, 12:14:59 PM

901, Rose F Kennedy Center

Dominick P. Purpura Department of Neuroscience

From pathways to precision medicine: The emergence of protein kinases as therapeutic targets

The cerebellar landscape in drug addiction. Have we been ignoring the elephant in the room?

Fragile X syndrome: aberrant signaling at the synapse

Developing disease modifying treatments for the Sacred Disease

LRRK2 and Lysosomes: Mechanisms of Pathogenesis in Familial Parkinson’s Disease

The dynamic epileptic brain

Stimulus triggers for action: Defining contributions of parallel dopaminergic circuits in reward

Speed in cortical dynamics confers temporal flexibility to self-initiated movements

Space-time in navigation and memory

Neural basis of economic choices

Cellular and circuit mechanisms supporting navigation learning in the hippocampus

Neural circuitry for context-dependent behavior and learning

Adaptive control of innate reflexes by visual cortex

How does the developing brain become epileptic? MicroRNAs, Microglia, and Memory

Investigating multiple myeloma in the bone marrow using in vivo imaging

Dissecting the circuit and molecular based mechanisms of drug addiction

Gating and regulation of connexin hemichannels

Neural circuitry controlling motivational aspects of aggression

Developmental dysfunction of VIP interneurons impairs cortical circuits

Mitochondria position, structure and function during axon development

Distinct timescales of population coding across cortex

Glia modulate the shape and function of neuron receptive-endings

Causal interrogation of decision making: a common mechanism for choice, reaction time, and confidence

Aberrant Rac1/cofilin signaling controls impaired spine structure, synaptic function, and sensory processing in Fragile X Syndrome

Neural circuits governing parental behavior

The brain’s gatekeeper: New approaches to study the formation and function of the Blood Brain Barrier (BBB) in health and disease

Protein dosage and neurological disorders

A fundamental microcircuit computation

Developmental origins of Huntington’s Disease

Decision related activity and top-down attentional modulations in primate V1

Attention, neural oscillations and entrainment: Novel phenomenology and the development of a normalized statistical approach

Unraveling the role of LRRK2: A key player in Parkinson’s disease

Sculpting the nervous system: Cellular and molecular mechanisms of neural circuit refinement

Neuronal computations in the mammalian retina

In vivo study of cortical synapse remodeling during peripheral immune activation

New insights into the regulation and consequences of dopamine release in the striatum

KDM5: a histone demethylase with important neuronal functions

Nanoscale analysis of hippocampal synaptic plasticity

Prefrontal control of visual cortical signals; Neuronal basis and neuromodulators

Connexin43 modulation enhances neuroprotection in stroke

Gap junctions of glia: Wiring principles of the non-neuronal elements of the brain connectome

Circuit-specific synaptic regulation by astrocytes

Illuminating the neural circuits underlying a tactile decision

Cellular and circuit mechanisms of persistent firing in a neural integrator

Variability, modulation, and robustness in neuronal circuits

Neuronal migration and brain map formation

On the neural circuits for face recognition: a vision science perspective on the social brain

Neuronal circuits involved in wakefulness

Cholesterol and the cochlea from ion channel biophysics to ototoxicity

The neurobiology of photophobia: How does light exacerbate migraine headache

Ion channels determine cell structure and make life/death decisions

Dynamic properties of thalamocortical synapses in the visual system in vivo

Synaptic mechanisms for visual computation in retinal circuitry

Weird ion, weird ion channel, misleading crystal structure, and a surprise

A neural code for sensory reliability in the sound localization system of the barn owl

Computational exploration of molecular permeation of a connexin channel

Circuit Logic of Sugar Reward

From vision to eye movements in the frontal eye fields

Signals and mechanisms regulating gap junction internalization and degradation

Autophagy in CNS synapses

Powering the brain: The glycolytic metabolon meets local energy demands at presynaptic sites

Alcohol 'habits' - how dorsal striatum neurodynamics encode alcohol cues

Protein translation and neurological disorders

Adaptation in V1 as inferences about natural movie statistics

From single neurons to networks in the retina and cortex

Electroconvulsive therapy for autism: role of oxytocin and serotonin signaling

Connexin- and pannexin-based channels as molecular targets to prevent neuroinflammatory responses

A light in the dark - algorithms for navigation and exploration in larval zebrafish

Anhedonia and antidepressant treatment mechanisms

An inside job: how endosomal Na+/H+ exchangers link to autism

Spatial regulation of gene expression during synaptic plasticity

Adaptive olfactory circuits in drosophila

Elucidating the role of AIDA-1 in synaptic transmission, plasticity and behavior

Molecular mechanisms of white matter injury in preterm infants with intraventricular hemorrhage

Stem Cell Joint Seminar "In vitro cell culture models to decipher brain development and neuronal integration"